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Changemakers

Biopharmaceuticals are drugs in which the active substance is manufactured or extracted from biological origin materials. They are usually produced in bioreactors by plant cells, microbial cells, yeast cultures, or mammalian cells. Also known as biomanufacturing, they are used to either treat or diagnose and prevent a patient’s medical condition or disease. Biopharmaceuticals are typically complex macromolecules administered by injection or infusions, and examples include vaccines, serums, and insulin.

Biopharmaceuticals

Cannabinoids are natural compounds obtained from the Cannabis sativa plant. Delta-9-tetrahydrocannabinol or THC is a psychotropic substance. Cannabidiol, or CBD, is non-psychotropic and often used for nutraceutical purposes. Cannabinoid equipment extracts THC and CBD from the plant and prepares the substance for formulations that treat pain, nausea, anxiety, and inflammations. Cannabinoids are processed in various forms, including creams, capsules, and oils.

Cannabinoids

The most important part of a capsule is its contents. But if the shell is not carefully made, the dosage ingredients inside lose effectiveness. From molding to sizing, capsule manufacturing equipment forms perfectly-matching husks ready for filling. The simplicity of encapsulation revolutionized pharmaceuticals since it was introduced in the 19<sup>th</sup> century. However, capsules are changing to increase delivery efficiency and reduce the dependency on gelatin.

Capsules

The topical route is a convenient route for the self-administration of drugs. But turning a pharmaceutical formulation into an easy-to-use cream involves specialized cream manufacturing equipment. Topical dosage forms are essentially an emulsion of oil and water.  But the ratios can be changed to process it into lotions, ointments, and gels.

Cream

Essential oils are known as the liquid gems of nature. The sweet-smelling essences impact not just our senses but also our biochemical and cellular make-up. Besides aromatherapy, the products of an essential oil extraction system found applications in pharmaceuticals and foods.

Essential oil

Parenteral preparations refer to drugs using non-oral means of administration. Injectables, such as needles and syringes, are used to deliver a drug into the systemic circulation directly in the veins, muscles, under the skin, or in the tissue.

These parenteral formulations are pharmaceutical dosage forms that have strict regulations on being sterile, pyrogen-free, and free from visible particulate matter including reconstituted sterile powders. Solutions, suspensions, emulsions, and gels with APIs intended for administration by injection are usually supplied in vials, ampoules, pre-filled syringes, or pens to facilitate ease of use.

Injectables

<p class="filterable-grid__description">Liquid dosage forms are designed for easy absorption. The body quickly carries the active ingredients through the system and triggers the required response. But the greatest advantage of this medicinal type is its flexibility in formulation and dispensation. From lotions and syrups to drops and sprays, liquid solutions can be adapted to different administration routes including parenteral, topical, and oral. The fundamental liquid dosage manufacturing process involves dissolving or suspending solutes in a fluid. But that is not enough. A precise blend of excipients is needed to make the medicine go down.</p>

Liquid dosage forms

Eating is more than just nutrition, but we have found ways to increase the nourishing power of our foods. Nutraceuticals manufacturing, from vitamin C powder and probiotics to omega 3 oil, is a concentration of natural ingredients and health supplements that complement our diets. While dietary supplements are not quite haute cuisine, the process of extraction and purification is no less a blend of science and art.

Nutraceuticals

Pharmaceutical powders provide longer shelf life and better stability than liquid dosage forms. But the processing of pharmaceutical powders is crucial for growing segments besides pharmacy. Functional foods and cosmetics formulated with active ingredients and excipients depend on powdered forms to fulfill their promises.

Pharmaceutical powder

Pharmaceutical developments walk side by side with health advances to provide new medicines, treatments, and therapies that have increased life quality and extended life expectancy by years. Pharmaceutical manufacturing equipment helps deliver products to a great deal of the population, but there’s a significant share that doesn’t benefit from them yet. Over 2 billion people cannot get the medicines they need, according to the United Nations Industrial Development Organization, and local production might be a way to provide for these people.

Pharmaceuticals

Ancient civilizations discovered that plant extracts were useful for the treatment of pathologies. The origin of plant extraction cannot be specifically verified, but we can infer that the earliest attempts at plant extraction were more intuitive than scientific. Today, the extraction of compounds is a precise process with plant extraction systems complimenting traditional knowledge.

Plant extracts

Whether for personal consumption or agricultural purposes, you process seeds to make them clean and maximize yield. Seed processing equipment includes the steps of polishing, threshing, separation, sorting, and drying. Some cases require additional processes. For example, the extraction of the seed from fruits or vegetables. Or, pressing the seed to extract oil.

Seeds

Among all dosage forms in use today, tablets constitute the most common one. They are pharmaceutical solid dosage forms containing active ingredients and excipients such as diluents, binders, glidants, and lubricants. Using tablet making equipment, these solid dosage forms are made by compression of granules or powder blends and then shaped by molding.

Tablets

The building blocks of matter have driven the imagination of philosophers, scientists, and artists for millennia. But, for manufacturers, these elements have a more concrete existence as powders. Powder processing technology conditions these primary materials to create a vast range of products, from chemicals and foods to pharmaceuticals and ceramics.

Powder

Liquid

Herbs have always been shrouded in mystery. The delicate plans produce overpowering bouquets and potent remedies. Herbal extraction technology gets to the core of this mystery and makes bioactive compounds available for a range of applications. Rich in antioxidants, anti-inflammatories, and aromas, herbal extracts are vital ingredients for medicines, foods, cosmetics, and wellness products.

Herbal extracts

Healthcare products are goods or services used to improve, maintain or prevent the deterioration of health or ease the consequences of illness. Healthcare products include a wide range of goods, from hospital clothing, over plasters, wound care products and diagnostic devices. These products must be clean and contamination-free, which is achieved with strictly regulated healthcare equipment.

Healthcare products

Granules

Syrup

Packaging Formats

Continuous

If you want to pack into eye-catching 4-side sealed sachets between 40x50 mm and 250x200 mm in size, investing in a reliable sachet machine will be a good investment.


<h2>Fast and flexible solution for your sachet needs</h2>
The Sachet Machine series SA 300 &amp; SA 600 by VikingMašek are continuous motion multi-lane sachet machines. They make eye-catching 4-side seal packets using just one roll of packaging film that can seal your product with high speed and efficiency.

The versatile multi-lane sachet machines can accommodate from 1 to 6 lanes (SA600) or from 1 to 10 lanes (SA600) to form sachet pouches, running as fast as 80 cycles per minute.

Designed to pack powders, dense, fine, loose and particulate materials as well as liquids and semi-liquids into 4-side sealed sachets and to accommodate different bag shapes including tear notches and easy-open system. They can be fitted with servo auger fillers &amp; volumetric fillers for powder applications, and two different liquid fillers for sauces or creams.

Sachet Machine

Bagging is the process of packaging measured portions of a product into bags that protect it from spoilage, enable easy and safe transportation, and secure the product against tampering and pilferage. The choice of bagging equipment depends on the desired mass or volume per bag, the flow characteristics of the product, and bag construction and design. Bags vary in size from small sachets to bulk flexible containers. Bagging systems are often the last processing step that is generally integrated into a production line.

Bagging

<span style="font-weight: 400">At last, you reached the final stage of processing your product - welcome to the packing world! Packing preserves and protects a product from damage, spoilage, and contamination while it makes its way from the production line to the consumer or further production. Depending on which industry your products belong to, the type of primary packaging equipment can change drastically. You need to pay careful attention to products with </span><span style="font-weight: 400">chemicals or hazardous substances since they can be potentially dangerous to human health. </span>

Packing

liquid

solid

If you are looking to pack your product into stick packs from 17 x 40 mm to 100 x 200 mm in size, you may benefit from the experience from the largest manufacturer of stick pack machines in Europe.


<h2>Benefit from the experience from Europe’s leading producer</h2>
This multilane Stickpack Machine series (ST200, ST400, ST560, ST800, ST1200 ) by VikingMašek can accommodate a large variety of different shapes of stickpack pouches with high efficiency and flexibility.

The versatile multi-lane stick pack machines can accommodate from 1 to 20 lanes, running as fast as 80 cycles per minute.

They are designed to pack powders, dense, fine, loose and particulate materials as well as liquids into StickPack bags and to accommodate different bag shapes including pour spouts, tear notches and easy-open system.

Semi- or fully automated cartoning solutions are also available for individual or bulk cartoning.

Stickpack Machine

If you want to accommodate multiple bag designs and dimensions with fast speed and accuracy, you need a smart automated packaging device.


<h2>High-speed quiet vertical form fill sealing</h2>
The VikingMašek Intermittent Bagmaker series (S250 /300, MS300, S400, S650) are perfect for packaging a large variety of bags. It can accommodate multiple bag designs and dimensions with high speed and accuracy. It can produce from 50-130 bags per minute and handles bag sizes from 40 x 60 mm (S250) up to 650 x 1000 mm (S650).

This vertical bag-maker is perfect for packaging small bags of snacks, candy, coffee, frozen fruit and for large bags of snacks, candy, coffee, pet food, powders, meat and poultry, bulk bags powders, wood chips, soil, grains and much more.

Bagger with servo driven jaw actuation

If you want to pack into unique bag styles like Quad-seal and Doypack, but you don’t require acceleration &amp; deceleration, you can save costs by choosing a bagger with a mechanical drive.


<h2>Steady speed vertical form fill sealing</h2>
The VikingMašek Intermittent Bagmaker series (M250, M400, M500 ) are high-performance vertical form fill and seal machines. Its rugged construction and enclosed jaw drive enables hassle-free packaging in dusty or wet environments.

It can accommodate multiple bag designs and dimensions with high speed and accuracy. It can produce maximum up to 70-100 bags per minute and handles bag sizes from 50 x 60 mm (M250) up to 500 x 600 mm (M500).

This vertical bagger is perfect for packaging quad seal, flat bottom, doy style, brick fold down/tape down, and pillow bags, snacks, candy, coffee, fresh and frozen fruit and more.

Bagger with mechanical driven jaw actuation

If you are looking for a compact packing machine that fits into tight space and tight budgets, proven basic bagging technologies may be your solution.


<h2>Compact and economic vertical form fill sealing</h2>
The VikingMašek Intermittent Bag maker series (E250, E400) is the most compact and economical bag maker for the packaging of small to large bags. It can produce maximum up to 50-60 bags per minute depending on the series of machine. Bag size can vary from 50 x 60 mm (E250) up to 400 x 600 mm (E400).

The robust, stainless steel, open-design frame is easy to access for maintenance. This vertical bagger is perfect for packaging small to large bags of snacks, coffee, pet food, hardware products and more.

Bagger with rotary jaw drive actuation

If you are looking for a compact packing machine that packs multiple smaller packs in one master bag; this automated product is exactly what you need.


<h2>Compact bag-in-bag machine for packing applications</h2>
The VikingMašek Intermittent Bag maker (M250 BiB) is a machine for all types of bag-in-bag applications, from airline/hotel single serves coffee packs to multiple smaller packs in one master bag. This Bag-in-Bag machine has enclosed, direct jaw drive, that provides you with years of smooth maintenance and free operation.

This vertical Bag-in-Bag machine is perfect for packaging from small to large bags of snacks, coffee, pet food, hardware products and more.

Bag-in-Bag machine

If you want to pack into gusseted and pillow style bags and packing speed is important for your packaging process, a continuous bagger with twin sealing jaws could be a good investment.


<h2>The world’s fastest vertical form fill sealing machine</h2>
The VikingMašek Continuous motion bag maker velocity is capable of high speed production up to 300 bpm. The unique center mounted filling tube and natural counterbalanced sealing profiles are designed to provide vibration free, extremely smooth operation at all speeds.

The Velocity is also extremely versatile, handling package sizes up to 300 mm wide and multiple package styles. Patented, independently phased, twin sealing jaws separate the velocity from all other high speed machines and virtually eliminate lost cycle time. This is the world´s fastest bagging machine on the market that has no competition.

Continuous bagger with twin sealing jaws

Want a machine to pack unique bag styles such as quad-seal and Doy-pack bags at incredible speeds; this is the machine for you.


<h2>Ultra-fast continuous motion bagger for unique bag styles</h2>
The VikingMašek Continuous Vertical bagger (Sigma 250, Sigma 400) is a fast bagging machine used to pack unique and different bag styles at high speed. The fast-action linear magnetic drives boast over 200 to 220 bags per minute depending on the machine series. With bag dimensions of up to 300 mm to 400 mm wide by unlimited length, plus a host of bag styles like Quad seals and Doypacks at incredible high speeds, the SIGMA is flexible, functional and high-tech machine.

Continuous vertical bagger

Batch

When you have a need to tailor make your conveyor and still have the high requirement on hygiene, e.g. in the food and pharmaceutical industries.


<h2>Tailor your own conveyor without compromising quality</h2>
The piFLOW®p from piab is the best option when a premium technology is needed.

It is built on standard modules and you can combine and change them in almost endless combinations. All parts still meet the high requirements of the pharma and food industries. So, you have the possibility to tailor your own conveyor without compromising on quality.

The design makes it very easy to use and install; offering with this wide of applications, such as powder and granules transfer or form-fill-seal or big bag loading and unloading drum/bag filling and emptying or Mill/Sieve/Mixer/Blender filling or tablet/fragile products transfer or applications in explosive atmosphere or hygienic applications or compact applications.

Premium vacuum conveyor

Classifying

Conveyor systems are used for moving materials from one location to another. Considerations for choosing a suitable industrial conveying system include the nature of the product, its physical state, the desired conveying rate, and sensitivity of the product to heat and mechanical shock. Conveying equipment is used in the food, pharmaceutical, chemical, biomass, and mineral industries to move materials around a warehouse as well as to transport bulk powders, granules, and grains for processing and filling. These types of systems are usually automated and there is a wide variety of solutions to choose when it comes to the type of conveyor. Types include screw, gravity, chain, roller and belt conveyors.

Conveying

Pusher centrifuges are continuously operating filter centrifuges and can have several basket stages depending on the application. Widely used for processing salts, fertilizers, but also plastics, soda and cellulose.


<h2>Continuous solids throughput under the toughest conditions</h2>
Pusher centrifuges from Ferrum are continuously operating filter centrifuges that are based on the very successful Sulzer Escher Wyss design. The slurry is fed continuously to the product acceleration disc via the filling pipe. The solids are transported out of the centrifuge basket into the discharge channel, from where they leave the pusher centrifuge. The cake is cleaned in the centrifuge by adding washing liquid on to the solid cake.

Various models have been developed with basket sizes ranging from 230mm to 1200mm. The most common applications are developed in agricultural and petrochemical industries, such as filtration for obtaining zinc sulphate, lysine, nitrocellulose, sea salt, sodium carbonate, urea, Glauber’s salt, potassium chlorate, potassium nitrate, linters and so on.

Pusher centrifuge

Industrial centrifuges are widely used for mechanical solid-liquid separation of components in the pharmaceutical and chemical industries. This is achieved by rapidly rotating the contents within a container to separate fluid of different densities or to remove liquids from solids.

Centrifuging

Industrial drying machines are designed to remove moisture from your product. But the drying process must cater to variations in the state of matter and molecular structure of the input material. Industrial dryer technology exploits the modes of heat transfer (convection, conduction, radiation, evaporative cooling) to control the moisture content.

Drying

Vertical Bottom discharge Centrifuges work discontinuously, discharging the solids to the bottom. They are suitable for the demanding continuous operation in the chemical and fine chemical industry or for complex pharmaceutical applications.


<h2>Efficient and reliable process cycles with low vibration</h2>
The Vertical Scraper centrifuges VBC (Vertical Bottom discharge Centrifuge) from Ferrum include many application areas in the solid-liquid separation due to the modularity and the comprehensive range of optional equipment. The solid-liquid separation is effected discontinuously in a sequence of specific process steps. The individual process steps last from a few minutes to several hours depending on the characteristics of the product.

The most common applications are in the paint industry with pigments; herbicides, insecticides and carbofuran in the agrochemical industry; antibiotics, vitamins, APIs and other intermediates in the pharma industry; and plenty of applications in the food industry.

Vertical scraper centrifuges

A vertical peeler centrifuge is used to separate solids, usually to separate fine particles from suspension liquid feed mixtures in the pharmaceutical industry, where the scrapped solids are discharged through the bottom of the centrifuge vessel.


<h2>Excellent inspection outside and below the centrifuge basket</h2>
The Vertical Peeler centrifuge is a new development of the centrifuge type VBC-S (Vertical Bottom discharge Centrifuge - Swivel Open Housing) from Ferrum and it was specially designed for use in the demanding pharmaceutical industry.

Pharmaceutical centrifuges are used for products that can be filtered with solids concentrations from 2 w% and particle sizes of minimum 4 μm. The continuous operation of centrifuge allows all process steps are carried out simultaneously, increases the overall throughput.

The most common applications in the pharma industry are in Active pharmaceutical ingredients (APIs), antibiotics, salicylic acid, pharmaceutical intermediate products, etc.

Vertical peeler centrifuge

Discharge solids vertically upward through manual action, optionally using a filter bag or a special suction device.


<h2>Optimally designed controls for easy, efficient operations</h2>
The top discharge centrifuges from Ferrum include many application areas in the solid-liquid separation due to the modularity and the comprehensive range of optional equipment. The applications of the vertical top discharge centrifuge, range from pilot plants, small-quantity production to production applications in the chemical and pharmaceutical industries.

Vertical top discharge centrifuge

The system is perfectly suited for pilot plants as well as small-quantity productions in the fine chemical and pharmaceutical industries.


<h2>Compact and mobile centrifugation</h2>
The mobile pilot plant centrifuge from Ferrum, combines centrifuge, control and drive components as well as inertisation system in one mobile turnkey unit. The system is perfectly suited for pilot plants as well as low volume production in the fine chemical and pharmaceutical industries. The solids are discharged vertically upward manually or using a filter bag.

Mobile pilot plant centrifuge

For transferring highly active pharmaceutical ingredients (HAPI) without contamination from the isolator centrifuge to the next process step (e.g. vacuum tray dryer).


<h2>Simple and efficient handling within the isolator</h2>
The VTC isolator centrifuge from Ferrum is designed especially for the use in an isolator.

This allows the operator contamination-free transport of toxic active pharmaceutical ingredients (HAPI) from the centrifuge to the next process step (e.g. vacuum dryer).

The solids are discharged from the basket either manually or by means of a lifting device.

The system is Suitable for pilot plants as well as small production quantities in the pharmaceutical industry.

Isolator centrifuge

For slurries difficult to discharge, a scraper can improve process reliability, efficiency, and operating cost. At reduced speed, the scraper knife swings into the filter cake and scrapes out the product vertically downward via the discharge chute.


<h2>Easy to access centrifuge for the best inspection</h2>
The HPZ 630-1600 range from Ferrum for pharmaceutical centrifuges HPZ range from pilot plants and low volume production to production applications in the demanding pharmaceutical industry. Ferrum pharmaceutical centrifuges are used for products that can be filtered with solids concentrations from 2 w% and particle sizes of min. 4 μm.

When expecting the processing area and the internals, the entire housing is swiveled open. An optional front door further eases and improves inspection. The centrifuges can be operated in an automatic, semi-automatic, manual or service mode. With the Horizontal pharmaceutical scraper centrifuge, a wide range of production recipes can be saved.

Horizontal pharmaceutical scraper centrifuge

The laboratory-scale active freeze-drying is used for dehydrating high-value products that are too sensitive for conventional drying processes. The product is dried by freezing and subsequent sublimation of ice formation, typically in vacuum and at low temperatures, in a small laboratory and pilot plant scale, enabling a smooth transition to the production plant.


<h2>Start innovating with freeze-drying technology</h2>
The 1-liter laboratory-scale freezer dryer from Hosokawa Micron is quicker and less labor-intensive than traditional tray-type freeze dryers. It offers the possibility of producing loose and free-flowing powder at low temperatures and low pressures, all in one vessel. Ideal for testing and simulating processes, the lab unit is "plug and play", including controls and all necessary equipment for reliable operation in your laboratory environment. Ideally suited for pharmaceuticals like antibiotics, collagens, APIs and electrolytes; food industry and special materials like nanomaterials, polymers, ceramics, pigments, fillers, limestone, catalysts, glass powder and salts.

&nbsp;

Laboratory scale active freeze dryer

When your product or process is sensitive to humidity, using an air dehumidifier may result in substantial savings on the running costs of your plant.


<h2>Precise humidity and temperature control</h2>
The Air dehumidifiers from Ventilex come in a variety of configurations depending on air volumes, temperature range, available energy, and any need for additional biocidal capacity. The systems keep the air at a constant, precise humidity regardless of weather conditions or load variations.

Any manufacturing or processing operation, that is humidity, temperature, or micro-organism sensitive, is a natural application for a dehumidification system. Whether your space conditions are 25 ºC and 20% RH, or 5ºC and 40% RH, or even –20ºC and –40ºC dew-point, the system can provide those conditions every day. The result is a better bottom line.

Ventilex Drygenic air dehumidifier is easy to operate, eliminates airborne micro-organisms, and saves energy and investment costs.

Air dehumidifier for bulk products

Industrial dehumidification involves the process of removing moisture as well as controlling humidity. For example, warehouses that store grains need a controlled climate to avoid mildew and other moisture-related issues that can ruin or spoil the product. Refrigerant and desiccant dehumidifiers are used to reduce or maintain the level of humidity. Refrigerant dehumidifiers pass the air over a cold coil, cooling the air to the point where its water vapor begins to condense. Instead, desiccant dehumidifiers pass the air through a rotor containing a moisture-absorbing material. Commercial dehumidifiers are somewhat similar to their industrial counterpart in terms of function. The only big difference is the scale at which the equipment is being used.

Dehumidifying

A belt dryer typically applies the product through an infeed chamber onto a perforated horizontal belt, which carries the product through the drying area which is divided into several sections.


<h2>Carefully controlled, high through-put, hygienic drying</h2>
The belt dryer from Ventilex is a stainless steel perforated horizontal belt, designed for durability, sanitation; it controls temperature and humidity as required, delivering desired levels even with varying air inlet conditions.

Helping the industry to produce better quality products, controlling temperature / humidity environment while minimizing utility usage and maximizing production rates. Besides the drying of food and agriculture products such as flaked, striped, noodle, cube and granule materials; it can also be used for dehydration of various chemical and pharmaceutical products.

The dryer capacity, size and performance depend on the available heat transfer area and the operating conditions for the specific product. The combination of temperature cycles and drying times can be adjusted to control the final product physical properties.

Hygienic belt dryer

Particularly suitable for research centers requiring greater freeze drying capacity. Some of the most common applications are galenic formulation, freeze drying experimentation, aliquot preservation, taxidermy, experimental food and so on.


<h2>The laboratory freeze dryer that is easy-to-use</h2>
The LyoAlfa from Telstar Life-Sciences is a compact laboratory freeze dryer. It comes as a console and is mounted on casters which make it easy to install. The unit is very flexible, allowing for the simultaneous freeze drying of bottles, vials or bulk products through the connection of different manifold systems or a chamber.

It is available in two models LyoAlfa 6 -50, with a final condenser temperature of -50 ºC; and LyoAlfa 6 -80, with a final condenser temperature of -80 ºC. This enables a higher freeze drying speed and is much more suitable for working with biological samples or products with very low eutectic or collapse points.

Compact laboratory freeze dryer

Formulation technologies are an integral process in many industries such as pharma and food. Chemical mixtures require strict handling to combine the separate ingredients into the homogenized recipe that makes your final product. Formulation technology stores, mixes and subjects the elements to a range processing parameters according to your specifications to develop the base material. The resulting formulas are then weighed, formed, packaged, or sent for further formulation.

Formulation

Designed for biological, pharmaceutical and food products formulation and "scale up" work.


<h2>Best performance for technology transfer activities and work in advanced R&amp;D Centers</h2>
The LyoBeta from Telstar Life-Sciences is a freeze drying unit for biological, pharmaceutical and food products formulation and "scale up" work, facilitating transfer technology to the R&amp;D centers and production. It is a high performance unit with a GLP design that allows for performing the entire freeze drying process fully automatically as well as accurately monitoring it. Very easy to clean, stainless steel chamber, condenser and plates; includes industrial components, such as sensors, vacuum pump, exchangers, etc.

Some of the most common applications are production in pilot plants, functional food research, preservation of diagnosis kits, small batches for clinical trials and so on.

Pilot freeze dryer for scale up

A multipurpose unit in the research and development field. Some of the most common applications are galenic formulation, freeze drying experimentation, taxidermy, underwater archaeology, aliquot preservation,  diagnosis and other research.


<h2>Start your research with this multipurpose high-performance device</h2>
The LyoQuest laboratory, multipurpose and R&amp;D freeze dryer from Telstar Life-Sciences has been designed as a multipurpose unit for the research and development field. It is a small freeze dryer, more compact than most but in spite of its small size, its capacity is quite unbeatable. A state-of-the-art control system and a range of specially designed accessories make the LyoQuest a benchmark in its category.

The unit's design offers the best performance in the least possible space. Suitable for laboratories: compact and easy to install, solidly designed laboratory equipment. On a functional level, cooling management ensures optimum performance.

Multipurpose and R&D freeze dryer

For either bulk format or liquid in vials, ampoules or syringes, the Lyomega units are designed for freeze drying high value products, such as: vaccines, cytostatics, antibiotics, biologicals, hormones, active ingredients, reactives, etc.


<h2>Integrated and customized solution for pharmaceutical production</h2>
The Lyomega from Telstar Life-Sciences offers design flexibility to tackle all the requirements for each project. Customization capabilities cover a wide range of engineered solutions, including two-door pass-through design and sub-doors for product loading and unloading at a constant level. Internal or external condenser systems can also be configurated in a horizontal or vertical position, adjacent to or below the chamber. Refrigeration systems range through a double stage or cascade reciprocating compressor, screw compressor or liquid nitrogen and a full range of customized CIP systems are also available.

Custom engineered freeze dryer

Designed to perform clinical trials, pilot, and small scale or large scale industrial drying processes, in accordance with the strictest GMP and Regulatory standards and in line with the latest freeze drying technology trends.


<h2>The right balance between specification, quality, cost and lead-time</h2>
The Lyonomic Series from Telstar Life-Sciences are state of the art freeze-drying systems, designed and engineered modularly to provide a comprehensive range of standard models and in-factory options.

Telstar freeze drying shelf inner channel design ensures high product homogeneity during the freezing, primary and secondary drying stages. The SCADA supervisory, control and data acquisition system designed by Telstar, allows the user to readily interpret the machine's operation and obtain information on the process required for decision making and batch reporting, all in compliance with FDA 21 CFR part 11 electronic record guidelines.

GMP freeze dryer

For processing a wide range of products: solid, porous and liquids in a laboratory environment.


<h2>Excellent performance for the sterilization of laboratory materials</h2>
The Sterilab autoclaves from Telstar Life-Sciences are steam sterilization units designed for processing and sterilization of a wide range of products: solid or porous products, as well as liquids: glass containers, culture media, cages, bottles, etc., also utilized for housing animals, laboratory waste, equipment and so on.

The saturated steam GMP laboratory autoclave offers a high technical performance adapted to a GMP setting in accordance with the applicable European standards: EN 285, PED, CE marking, etc.

In the biopharmaceutical industry the units are used for applications that are not necessarily GMP production related, such as decontamination processes, R&amp;D, biological control, etc.

Saturated steam GMP laboratory autoclave

Industrial sterilization processes are employed in different industries to completely eliminate all living microorganisms from the final product. For instance, in food processing, sterilization equipment is used to produce a stable product with a long shelf-life by eradicating harmful bio-contaminants. Instead, in the medical field, sterilization technologies aim to prevent the transmission of microbes to patients by sterilizing all the tools and medical devices that come in contact with the patient. Most sterilization equipment, such as autoclaves, employs high-temperature pressurized steam to destroy bacteria and disinfect surfaces from spores. Other methods include radiation sterilization or using chemicals such as hydrogen peroxide for disinfection.

Sterilization

When sterilizing and dealing non-thermolabile products, you will want to get a hold of those resistant to the temperature and humidity conditions of this method; in the pharmaceutical and in biotechnology industries.


<h2>Ergonomics and flexibility</h2>
The Sterimega autoclaves from Telstar Life-Sciences are steam sterilization units designed for processing a wide range of materials: solid or porous products and also liquids in pharmaceutical production. The units offer high technical performance and GMP design in accordance with the applicable European standards: EN 285, PED, CE marking, etc. Every unit, being a GMP autoclave, can be customized by adding various technical features that will positively enhance the performance to meet any requirement.

The most recognized sterilization method when dealing with non-temperature sensitive products in applications such as liquids in sealed, thermal shock resistant, containers: injectable in ampoules, vials, and so on.

GMP autoclave

Specially designed for sterilizing large batches of parenteral solutions.


<h2>The best performance for the terminal sterilization of parenteral solutions</h2>
Steridelta A autoclaves from Telstar Life-Sciences are steam and air mixture sterilization autoclaves specially designed for sterilizing large batches of parenteral solutions.

A mixture of pure vapour and air is used for sterilization. When the chamber has been loaded, steam is introduced and mixed with the air; therefore no vacuum pump is required. One or more fans, located at the top of the chamber circulate the air and steam mixture. The purpose of these elements is to achieve good temperature uniformity inside the chamber as soon as possible.

The units have high technical performance, GMP design and comply with the applicable European standards: PED, CE marking, etc. They have a compact, modular structure allowing for quick installation and commissioning.

Steam and air mixture sterilization autoclave

Specially designed for sterilizing large batches of parenteral solutions.


<h2>Excellent temperature uniformity can be rapidly obtained in the chamber by the high volume water flow</h2>
Steridelta W autoclaves from Telstar Life-Sciences are superheated water sterilization autoclaves specially designed for sterilizing large batches of parenteral solutions. The units have a high technical performance and GMP design in accordance with the applicable European standards: PED, CE marking, etc. They have a compact, modular structure allowing for quick installation and commissioning.

In terms of effectiveness, the Superheated water shower autoclave, has been designed and constructed to enable the process to be rapidly validated and it has a reliable control system that provides a homogeneous and repeatable temperature distribution in the chamber.

Superheated water shower autoclave

Designed for the terminal sterilization of temperature sensitive medical-health products in large batches.


<h2>The most efficient sterilization agent</h2>
EtO autoclaves from Telstar Life-Sciences offers the best performance for the terminal sterilization of temperature-sensitive medical-health products not to mention that they are custom-built to each customer's specific requirements. This Ethylene Oxide sterilization chamber has high technical performance, GMP design and complies with the applicable European standards: PED, CE marking (including ATEX), etc. The units are constructed in modules which require a certain level of expertise during the installation and commissioning. Given the risks involved with ethylene oxide as a carcinogenic agent, GMP specifies that this type of sterilization should only be used if there is no other alternative available.

Nevertheless, these medical devices are thermo-sensitive and delicate products. In this case, investment in sterilization equipment using EtO is fully justified.

Ethylene oxide sterilization chamber

Specially designed for the drying and sterilization of glass containers, vials or ampoules, and high-temperature resistant metal products using ultra filtered hot air.


<h2>Sterilize high-temperature resistant products using ultra filtered hot air</h2>
The Pyromega ovens from Telstar Life-Sciences are designed for the sterilization and/or depyrogenation of pharmaceutical and biotechnology products, such as glass containers, vials or ampoules and high temperature resistant metal products using ultra filtered hot air in Class 10,000 (ISO 7) or Class 100 (ISO 5). The units are supplied in a compact format with all components readily accessible and can be installed to span two rooms; one for loading and the other clean or sterile unloading room.

The design of the Dry heat depyrogenation oven offers excellent performance for processing materials utilized in the sterile or aseptic area and/or finished product terminal sterilization.

Dry heat depyrogenation oven

Pure steam is defined as the steam which when condensed becomes WFI quality water in accordance with European and US Pharmacopoeia specifications.


<h2>Low energy solution when steam is not yet available on site</h2>
The PSG-E electrical pure steam generators consist of a vertical pressure container, in the form of a column. Electrical elements are installed at the base to heat the water. The steam flows vertically upwards, but due to the effect of gravity the water droplets do not exit the chamber. The water is supplied preheated in a tank, also containing electrical elements, where degassing occurs. The system is supplied as a compact unit on a skid, with all components readily accessible.

The PSG-E from Telstar Life-Sciences is a generator capable of effectively separating pyrogens, which are used for the production of pure steam. Clean steam is defined as the steam produced from water free from additives.

The most common applications for this device is in the pharmaceutical industry and in biotechnology for autoclave sterilization feeding and for routine SIP sterilization in production reactors, freeze dryers, and production line filters and pipes.

Electrical pure steam generator

Pure steam is mainly used in the pharmaceutical industry and in biotechnology for sterilization, water for injection generation, clean room humidification.


<h2>Compact steam generator for pharmaceutical production</h2>
The PSG pure steam generator from Telstar Life-Sciences has a design which offers excellent performance for steam production for use in pharmaceutical production.

It consists of a vertical pressure container, in the form of a column divided into two parts. The lower part consists of a tubular heat exchanger, with a double tube sheet (DTS), connected at the top to an expansion chamber or separating column, which allows the steam to flow upwards and prevents water droplets from exiting the chamber.

To improve the energy efficiency, the preheated water is introduced into a tank with an exchanger, where degassing occurs. The system is supplied as a compact unit on a skid and all its components are readily accessible.

Pure steam generator

<span style="font-weight: 400">The heating process is a step of raising the temperature of food, pharma, cosmetics, and many other types of products. You may employ different heating solutions for this process, depending on the type of product you intend to manufacture. Selecting the appropriate heater machine for your product is quite important since various products require different ranges of temperatures and different ways of heat transfer using exchangers. Industrial heating equipment varies in two ways - the type of material it can process and the reaction you want to achieve.</span>

Heating

Freeze dryer designed for aseptic and small-scale production of high-value products.


<h2>Industrial freeze dryer in a compact envelope</h2>
Lyotris from Telstar Life-Sciences is a lab scale production freeze dryer designed for the production of small batches of high-value pharmaceutical products. With a 1m2 loading surface and capacity for approximately 1,600 10R-type vials or 30 liters of bulk product. It has been specially designed for aseptic production in vials or in bulk and its novel fascia and door design provides easy isolator integration.

The GMP laboratory freeze dryer comes with all  the necessary components for an automatic cleaning (CIP) and steam sterilization (SIP) processes, filter integrity testing (WIT) and also incorporates an advanced SCADA system which includes Telstar's patented ‘Lyometrics' system; providing advanced real-time information on the freeze-drying process.

GMP laboratory freeze dryer

Highly Purified water is used in the preparation of medicinal products where bacterial endotoxins need to be controlled, except where water for injection is required.


<h2>Fully compliant water purification in flexible executions</h2>
The purified water systems from Telstar Life-Sciences are specially designed to generate purified water in accordance with the International Pharmacopoeia specifications for Purified or Highly Purified water; and in full compliance with cGMP guidelines as per FDA and EMEA, EP, JP and USP requirements.

Offering two flexible outputs:  from 300 to 10,000 L/h with Oasys and from 100 to 10,000 L/h with Genesys. The Genesys system is designed to allow automatic hot water sanitization of the complete unit including the pipework feeding the purified water into the storage vessel, whereas the Oasys system works with chemical sanitization.

Purified water systems

Industrial filtration equipment separates solid matter from liquid by using a filter medium. The filter allows only the fluid to pass through but retains the solid matter. The choice of filtration equipment depends on the particle size, the consistency of the mixture, and the nature of your product.

Filtration

Purification is the removal of contaminating substances and by-products to increase the level of purity of the desired substance. Considerations for choosing a suitable purification system in the industry, include the physical state of the mixture, the desired product, required level of purity, the type of mixture, heat sensitivity of the product, number of purification steps needed, and the production volume. Industrial purification systems are used for the production of pure water in the food pharmaceutical and biotech industries.

Purification

Create a physical barrier between the operator and the product. More flexible than an isolator, a RABS is open, in most cases, so the air flows freely out of the RABS and into the surrounding room.


<h2>Protect the product from contamination without losing access to the process</h2>
The RABS from Telstar Life-Sciences provide protection by delivering an aerodynamic barrier over a critical process zone and bio-decontamination is usually manual. RABS when installed in ISO 7 environments already have a good class of cleanroom air therefore the RABS can provide ISO 5 in the critical zone.

Because RABS are being used more and more in aseptic processing they have developed to an extent where there are various types, such as the Closed RABS (cRABS), which consists in air passing through the critical zone, and it is filtered before it spills into the cleanroom or is recirculated back through the supply filters of the RABS.

Restricted-access barrier systems

The essential objectives of containment systems are personnel protection and preventing the release of toxic or infectious material into the environment. Containment is also used to prevent a product or sample from contamination by the external environment. In the chemical and pharmaceutical industries, containment solutions are used to protect the personnel from the leaking of airborne particles of hazardous substances, as powders or liquids are handled or transferred during processing.

Containment

Designed for sterile product and Potent API’s either with low or high OEL requirements.


<h2>Advanced aseptic processing from full filling lines to stand alone single isolators</h2>
The aseptic barrier systems from Telstar Life-Sciences work providing product protection in all process areas against external environment, operator and bacterial growth contamination. Airflow systems may be unidirectional or turbulent. Interfaced with H2O2 generators to provide validated automated surface sterilization internal to the Isolator.

From full filling lines to stand alone single Isolators, barrier systems are designed to provide solutions adhering to regulatory standards and guidelines. Running at positive pressure during normal conditions with auto change to negative in the unlikely event of system breech, when toxic products are involved.

Telstar Aseptic Barrier Systems are guaranteed to comply with relevant standards and demands set by the regulatory bodies to ensure conformance and clients satisfaction, including: ISO 14644-1 Cleanroom &amp; Associated Controlled Environment, FS 209E Airborne Particulate Cleanliness, cGMP Guidelines (current Good Manufacturing Practices), ISPE guidelines (The Society of Pharmaceutical and Medical Device Professionals), FDA (Food and Drug Administration, MCA (Medical Control Agency), and  American Glovebox Society Guidelines.

Aseptic barrier systems

A high-performance transfer port system that combines ultimate safety, simplicity of operation, and ideal cleaning, used in pharmaceutical and biopharmaceutical manufacturing.
<h2>High-integrity locking system, preventing accidental containment breach</h2>
The Containment Transfer System (CTS) product range from Telstar Life-Sciences is a versatile combination of technologies that provides you with the flexibility to safely and securely transfer products in high containment environments. A number of sizes and design options are available to suit your containment requirements, security needs, and budget.

Contained transfer systems are specially designed as the safest method for transferring product/waste or items in or out of contained or sterile areas. Totally mechanical system (no power needed) with safety devices to prevent incorrect operations (not operator dependent) and with color indicators on the locking mechanism provide visual feedback of the transfer's port status.

Transfer system for high-containment environments

Testing device of the containment capability of gloves, which is as important as the other parts of the integrated system; and a simple, accessible means of checking interface integrity is critical.


<h2>Testing system to enable fast, easy measurement of glove containment efficiency</h2>
Glove Tester from Telstar Life-Sciences is a low cost manually operated single port testing device designed to allow both in situ and offline testing.

Constructed of acetyl or 316L stainless steel, the device uses air pressure to check glove integrity. It can be designed to suit all types of Telstar ACE glove ports as well as other port brands. The tester inflates the glove at +500Pa pressure for a period of at least five minutes. A leak is indicated by a drop in the pressure reading of the display gauge. An optional colour indicator gives an instant pass/fail assessment.

Glove tester

Industrial measurement equipment is used as a crucial step before products leave the production line. These measuring instruments check for correct dosage and standards. Equipment for measurement and control employs a wide range of technologies to detect inconsistencies in volumes, sizes, weights, and fill levels as well as to inspect goods for quality against a set of criteria. Specialized measuring tools allow you to minimize the probability for error to its lowest possible, ensuring that both products and packaging meet your benchmarks.

Measurement &amp; Control

Complex processes call for continuous tracking and monitoring systems that help you to keep the manufacturing operation under control. The technology analyzes the components in the production phase for divergence in behavior or changes in conditions. Based on advanced software applications, monitoring platforms make sure that your products satisfy the quality criteria while they are being developed.

Monitoring

Drawing samples and testing them for conformity with preset quality standards allows manufacturing units to produce a consistent quality of the product. In a batch process, sample testing systems ensures that each batch meets the specified standards. In a continuous process, product and materials testing helps in the early identification of quality issues, saving significant time and resources, and preventing a sub-standard product from reaching the market. The selection of industrial testing equipment depends on the identification of key quality parameters. These parameters may include volume, weight, viscosity, hardness, particle size distribution, sterility, gauge and containment, among other parameters. Testing machinery need regular calibration to ensure that the parameters being tested are accurate. Some of the more common testing solutions include thermal imagers, scratch testers, optical inspectors and texture analyzers.

Testing

Designed to allow operators to perform sterility testing in an aseptic environment providing assurance of material integrity.


<h2>For ultimate containment of all API and potent compounds, where the containment capability is crucial</h2>
The Half-suit tester from Telstar life-Sciences is the most likely component of the isolator which mission is to suffer wear and tear and thus develop leaks. Due to it works in the critical zone, guarantees special attention at the design stage and when monitoring protocols are developed.

The containment capability of half-suits is therefore as crucial as any other part of the integrated system, and a simple, accessible means of checking interface integrity is critical.

Telstar ACE offers custom-built testing systems to enable fast, easy measurement of half-suit containment efficiency. The Telstar Half-suit Tester is designed to allow both in situ and offline testing.

Half-suit tester

Provides the highest levels of operator protection from potentially harmful airborne contaminants generated during manual powder handling operations such as sampling, charging and dispensing.


<h2>Remove airborne particles from the operator's breathing zone</h2>
The downflow booth from Telstar Life-Science operates on a re-circulatory airflow principle. Clean laminar flow air is supplied from the ceiling, suppressing any dust clouds generated during any processing operation and removing airborne particles from the operator's breathing zone (OEL &lt; 100 µg/m3).

The fact that the booth works with a net inward airflow, ensures airborne contamination cannot escape into the external environment completing the many advantages of this effective containment system.

Down flow booths are frequently used in Pharmaceutical, Cosmetic, fine Chemical, Food and Nanotechnology industries.

Downflow booth

Designed to avoid this risk and protect the product from both the process and externally generated factors that would compromise its quality.


<h2>Perform sterility testing in an aseptic environment providing assurance of material integrity</h2>
The Sterility test isolators from Telstar Life-Science range of rigid wall Sterility are designed to avoid this risk and protect the product from both the process and externally generated factors that would compromise its quality.

Sterility testing of sterile pharmaceutical products is required by the Pharmacopoeias to determine acceptability of a production lot. It is an essential element of sterilization validation and it must be performed in a manner which avoids the risks of both false positive and false negative results.

It is suitable for performing both Direct Inoculation and Filter Membrane sterility tests with flexibility to be bio-decontaminated by different types of bio-decontamination systems available.

Sterility test isolators

HEPA filtered vertical laminar airflow (down flow) creates an ISO 14644-1 (Class 5) work area and prevents ambient air entering the work area, ensures product protection.


<h2>Create a class 5 work environment for non-hazardous materials</h2>
Telstar vertical clean benches ensure optimum product protection with HEPA filtration. Heavy duty construction and reliability make them convenient in the long term for all sectors of application and environments. Vertical laminar flow cabinets can be made in special sizes and can be customized to suit particular applications.

Special models have been developed to create the optimum work environment for PCR (polymerase chain reactions) and for lab environments. Down flow booth models are available that work fully with recirculated laminar HEPA filtered air (Telstar V-100) or partially recirculated laminar HEPA filtered air (Telstar V30/70).

Vertical laminar flow cabinet

HEPA filtered horizontal laminar airflow (crossflow) creates an ISO 14644-1 (Class 5) work area and prevents ambient air entering the work area, ensures product protection.


<h2>Particularly well adapted to hospital, control laboratories and life science environments</h2>
Horizontal Laminar Flow benches from Telstar Life-Science have a wide and high working space with a continuously flushed frontward by a particle free HEPA filtered and laminar airflow; which speed prevents contamination from operator and lab environment. The laminarity of the flow prevents cross contamination between the items handled in the working space.

Offering the highest product protection possible in an open system. It makes them particularly suitable for the handling of non-hazardous products, sensible to dust and/or to contamination such as injectable medicines, cell and tissue cultures, food sample preparation for sterility testing as well as micromechanics, optics, electronics.

Horizontal laminar flow benches

HEPA filtered horizontal laminar airflow (cross-flow) creates an optimized free space for manipulation with ISO 14644-1 (Class 5) conditions.


<h2>Compact booth that offers easy access to manipulate non-hazardous products</h2>
Mini-H from Telstar Life-Science are Horizontal laminar flow benches which offer the highest product protection versus dust and contamination in an open cabinet for non-hazardous samples such as cell and tissue cultures, food testing preparation, injectable medicine preparation. It also fits for micromechanics, optics and electronics.

The Compact horizontal laminar flow bench comes with HEPA filtered air; it's particle free and flushes the product preparation space with laminar flow, preventing direct or cross-contamination.

Thanks to its very compact size, Telstar Mini-H permits the installation of a product protection cabinet near the place where the product is utilized.

Compact horizontal laminar flow bench

This handy device offers the most advanced features in product-operator protection and user-friendly ergonomics to allow best working conditions and results.


<h2>Protect to the operator, product/materials and environment under class II conditions</h2>
BioULTRA from Telstar Life-Science is a top range class II cabinet aimed to provide protection to the operator, product/materials and environment. It is certified according to European Standard EN 12469 and also meets NSF 49 (class II type A2 /B3) and BS 5726:2005 main requirements. It is suitable for handling pathogenic agents of levels 1, 2 and 3 in the fields of pharmaceutical, academic research centers, biotechnology, hospital and medical labs, QA control labs.

Motorized sash window with inflatable gasket, filter clogging calculation and a simplified fumigation process minimize maintenance cost and time.

Remote PC Ultra logger control suitable for P3 lab.

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