Insertion technology for sterile blow/fill/seal systems
Ensure sterility and precision in liquid pharmaceutical packaging by integrating insertion technology into your blow/fill/seal operations, maintaining Class 100 environments without human intervention.
Inserts and Seals Sterile Liquid Containers
Weiler Engineering, Inc. offers the ASEP-TECH® Blow/Fill/Seal System with integrated Isolation/Insertion Technology, designed for pharmaceutical, ophthalmic, and nutraceutical sectors. This system uses barrier isolator technology to maintain Class 100 conditions, ensuring sterile insertion and sealing of liquid formulations. It supports applications in injectables, eye care, and respiratory therapy, producing end products like vaccines and IV saline solutions. The automated system seamlessly handles sterile inserts such as caps and stoppers, using a rapid transfer port to index them for insertion into molded containers, which are then securely sealed. This process, devoid of human intervention, guarantees a high sterility assurance level. The system is compliant with GMP and FDA standards, making it ideal for high-speed, continuous operations. It offers customizable configurations to fit specific production needs, and its designed integration with existing processing and packaging lines ensures a streamlined production flow.
Benefits
- Ensures maximum sterility with Class 100 environment, enhancing product safety.
- Streamlines production by integrating insertion and sealing in one automated process.
- Reduces contamination risk with barrier isolator technology and no human intervention.
- Meets regulatory standards, facilitating compliance with GMP and FDA requirements.
- Customizable design adapts to specific production needs, improving operational efficiency.
- Applications
- Ophthalmics,Liquid formulations,Nutraceuticals,Large volume parenterals (lvps),Respiratory therapy,Small volume parenterals (svps),Injectables,Eye care
- End products
- Preservative-free eye drops,Insulin preparations,Vaccines,Liquid dietary supplements,Multivitamin liquids,Iv saline solutions,Inhalation solutions,Artificial tears
- Steps before
- Purification,Loading inserts,Sterile preparation
- Steps after
- Sterility assurance,Final top closure,Packing
- Input ingredients
- sterile inserts,tip assemblies,cap assemblies,multi-entry rubber stoppers
- Output ingredients
- molded containers with inserts,final top closure formed containers
- Market info
- Weiler Engineering is known for designing and manufacturing advanced aseptic processing technologies, particularly its innovative Blow/Fill/Seal (BFS) systems, which provide efficient and sterile liquid packaging solutions for the pharmaceutical and healthcare industries.
- Sterility assurance
- Class 100 conditions
- Automation level
- No human intervention
- Insert types
- Tip and cap assemblies,multi-entry rubber stoppers
- Insertion method
- Integrated with B/F/S machine
- Environmental condition
- Class 100 controlled environment
- Transfer port type
- Rapid transfer port
- Location
- Outside the machine room
- Sterility method
- No terminal sterilization needed
- Barrier isolator
- Used for isolator loading
- Working Mechanism
- Isolation/Insertion with barrier isolator
- Integrated Steps
- Sterile insert loading and sealing
- Environmental Conditions
- Class 100 controlled environment
- Sterility Assurance
- High level,no human intervention
- Insert Type
- Tip,cap assemblies,multi-entry stoppers
- Automation Level
- Fully automated under controlled conditions
- Sterility Assurance
- High
- Container type
- Blow/Fill/Seal
- Control panel type
- Touchscreen HMI
- Integration possibilities
- Barrier isolator integration
- Sterile insert options
- Tip and cap assemblies,multi-entry rubber stoppers