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During crime scene investigations in any movie, you've probably seen forensic scientists collecting evidence and biological samples in small containers. Here, these are the vials, used to store medicines, especially in liquid form, or laboratory samples. Often made of glass or plastic, vials can be labeled as single-dose vials or sterilized and reused more than once. They are also available with various closure systems depending on the material and storage requirements.

What vials equipment do you need?

Benchtop peristaltic dispenser

When filling vials and ampoules, high standards of hygiene are required to avoid the risk of ...

Laboratory liquid viewer for colored glass bottles

In the pharmaceutical industry, an inspection to detect any particulat...

R&D bottle washer

Manufacturers of products that use bottles, vials, syringes, and test tubes as containers need to wash them...

Semi-automatic vial crimper

In a small production line, crimping vials manually can cause fatigue to the operator due to mul...

Benchtop piston filling equipment for vials in trays

Vials are difficult to fill individually through manual methods due ...

Pharmaceutical rotary labeling machine for vials

Small, cylindrical-shaped glass bottles or vials are mainly used for vacc...

Labeling machine for BFS containers

The pharmaceutical sector is unquestionably one of the major industries that rely on th...

Entry-level filler for large-volume parenterals

Large volume parenterals are unit-dose containers that are larger than 100...

Packaging machine for syringes in trays

Pre-dosed syringes are rapidly becoming the method of choice for the delivery of in...

Continuous pack cartoner

High volume automatic cartoning is vital for large scale production of cosmetic or pharmaceutical pr...

Horizontal cartoner for pharmaceutical applications

Automatic cartoning for cosmetic or pharmaceutical products is a requ...

Online fraction collector for offline bioprocess analysis

Many bioprocesses require offline analysis of samples to monit...

Start-up sterile filling line for injectables

For smaller-scale production of vials and syringes for the injectables marke...

Table top sterile filling line for injectables

Where a compact solution is required for filling vials for the injectables ...

Vacuum mixer for suspensions

The production of high quality pharmaceuticals often requires mixing of suspensions and similar...

Cleaning and sterilization systems

An increasingly vital part of high quality pharmaceutical production is a dedicated Clea...

Rotary vial washing machine

When washing vial, ampoules, or cartridges for pharmaceutical production there is often a trade-...

Industrial vial capping machine

The high capacity production of pharmaceuticals delivered in vials and cartridges requires a...

External vial washing machine

Exterior washing solutions for vials often suffer from high water consumption and low throughp...

Aseptic vial cap sealing machine

Aseptic production methods are at the heart of the latest development in pharmaceuticals in...

Vial sterilization tunnel

Sterilization of vials, ampoules and syringes before filling is a vital step in the production of ...

Vial filling machine

The volume filling of vials, cartridges and syringes is a vital part of the production of a wide range o...

Aseptic automatic vial filling machine

Current and future developments in pharmaceuticals increasingly rely on aseptic prod...

Aseptic automatic vial washing machine

The production of the latest high value pharmaceuticals often requires aseptic handl...

Automatic vial tray loader

In modern pharmaceutical production, end-line processes are often still manual or slow. This can ...

Nested syringe filling machine

Increasingly, pre-sterilized Ready To Use (RTU) nested vials, cartridges and syringes are the...

Sterile compounding system

Hospitals and compounding centres have traditionally used manual aseptic compounding processes. A...

Feeder with flexible wall hopper

The varying properties of dry powder products mean that specialized feeders are required fo...

Small feeder with flexible wall hopper

In many laboratory applications and production processes, smaller quantities of powd...

Magnetic agitator

Reliable mixing and agitation are essential to any quality production process that involves a fluid. This n...

High-capacity horizontal cartoner for pharma and cosmetics appliances

Cartoners take carton blanks which are formed and...

Automatic cartoner for applications in pharma and cosmetics

For high capacity production of cosmetics and pharmaceutical...

Pharmaceutical and cosmetic industry products cartoner

A large number of cosmetic and pharmaceutical products are packed ...

Horizontal cartoner for pharma and cosmetics

Most pharmaceutical and cosmetics products are packed in cardboard cartons fo...

High capacity cartoner for pharmaceutical applications

Many pharmaceutical products are packed in protective and decorati...

Vertical cartoner for pharmaceutical applications

Many pharmaceutical and cosmetic products are sold in protective and de...

Flexible automatic inspection machine for ampoules, vials, cartridges

If you are looking to improve the efficiency of y...

Small automatic inspector for ampoules, vials, or cartridges

Inspect small batch production of ampoules, vials, or cartr...

Semi-automatic inspection machine for ampoules, vials or cartridges

If you need to increase the efficiency of your manu...

Visual and HVLD inspection for ampoules, vials and cartridges

Do you need to improve the efficiency and capability of yo...

Sterile filling line for injectables

Sterile filling of liquids and powders for the pharmaceutical and cosmetic industries ...

Microdosing machine for sterile powders

Fill sterile pharmaceutical powders into vials under aseptic conditions with a spee...

High-speed aseptic injectable vial filling machine

Fill up to 24,000 vials per hour with pharmaceutical powders or liquid...

High-speed blister machine

If you are looking for a compact machine that produces blisters with an output of up to 700 blist...

Horizontal intermittent motion cartoner

User-friendly cartooning solution with an intermittent motion for a wide range of p...

Horizontal continuous motion cartoner

An automatic cartoning machine designed for both high-speed operations and medium pac...

Depyrogenation tunnels for ampoules, vials and bottles

Sterilize and depyrogenize ampoules, vials, bottles and similar gl...

Aseptic liquid filler for vials

Compact modular aseptic filler of vials with parenteral medicines and freeze-dried products.

Dosing machine for nonfree-flowing powders

Fill poorly flowing powders, dry syrups and similar substances into various gla...

Monobloc small volume liquid filler

These intermittent motion monobloc machines are designed for filling various liquids in...

High-speed small volume liquid filler

Fill liquid pharmaceutical, nutraceutical and cosmetic products in ampoules and bottl...

Case packer for cartons and bundles

Pack cartons and bundles into RSC (Regular Slotted Case) cases and perform functions li...

Stretch bander

A compact wrapping machine to seal your boxes with a max speed of 50 packs per minute.

Vertical cartoner

A cartoning solution that can be operated in either continuous or intermittent mode depending on the carton...

Small bottle checkweigher

Any small-diameter bottle, containing prescription medication or cosmetic applications, can be pro...

Versatile checkweigher

This Versatile checkweigher is equipped with a highly versatile strain gauge load cell. It is also sui...

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Tell us about your production challenge

When selecting production equipment for a production plant, it is important to talk to someone with experience in your field. Our industry experts have experience with various industrial applications. We’d love to help you!
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A vial for every application

Vials really do have millions of uses based on the material and application. Glass vials have been used for hundreds of years to store liquid pharmaceutical products. But glass is not always the same. For instance, The United States Pharmacopeia (USP) classifies glass into borosilicate glass as Type I and soda-lime-silica glass as Type II and III, with the difference being that  Type II has a special treatment to increase hydrolytic resistance.

Borosilicate glass contains at least 5% of boric oxide and is used for injectables with acid, neutral and alkaline pH. Amber-colored vials, created by adding iron to the glass, protect the substance from UV light and are suitable for light-sensitive samples.

 

Plastic vials, made of polypropylene or polyethylene, are widely used in cosmetics and law enforcement agencies. Compared to glass vials, they have lower chances of leaching and are much easier to handle. Plastic vials have excellent resistance to bases, alcohol, and acids. Special vials are also made for specific applications like cryogenic or liquid scintillation. Cryogenic vials are made of special polypropylene material to withstand extremely low temperatures. Scintillation vials are mostly glass vials used in liquid scintillation counting; this process is used to measure the substance’s radioactive activity.

Single-dose vials or multi-dose vials?

In medical applications, single-dose and multiple-dose vials are available. Single-dose vials are intended for one-time use and do not contain anti-microbial preservatives. The contents must be used within an hour after opening and any remaining contents must be discarded. These vials must be appropriately disposed of afterward. Multi-dose vials contain more than one dose of medication and contain anti-microbial preservatives to prevent the growth of bacteria after opening. It must be used for a single patient as much as possible to avoid cross-contamination and must not be used after the beyond-use date indicated on the label.

Coat your vials to improve chemical resistance

Glass delamination occurs in the inner surface of the container when exposed to chemicals due to chemical reactions and leaching of elements from the glass. As a result, glass flakes appear mixed with the chemical solution. If you think about it, this is a serious quality issue. Leaching of elements from the glass, such as sodium affects the pH level of the solution over time and may even lose the product’s efficacy.

As a solution, glass vials are treated by the vapor phase deposition silanization (or siliconization) method. This process involves applying a silicon solution to the surface as a protective layer to minimize the interaction between the vial and the substance. This method provides a uniform glass coating that improves the chemical resistance and gives a low adsorption characteristic preventing chemicals from sticking to the surface.

Aseptic vial filling equipment to ensure the safety of pharmaceutical products

Aseptic filling is fundamental in pharmaceutical industries to guarantee the quality and safety of its products from contaminants that may cause a reaction to the product leading to health risks when used. Exposure to contaminants also deteriorates the product quickly. The filling process starts with a vial washer before it goes to depyrogenation tunnels to remove pyrogens such as endotoxins and exotoxins. After sterilizing, vials are filled and stoppered by vial filling equipment. Then, they go to the capping and crimping machine for sealing.

Vial labeling and serialization equipment for product traceability

Serialization is a process used for product traceability operations. Information such as production-expiration date, lot number, and serial numbers are stored in a data center. By assigning a unique code to a drug packaging, counterfeiting of drug products can be prevented. Serialization is usually integrated with the labeling process of the vials. A high-resolution printer writes the labels with all the information required and then a code-reading camera is used during the verification process for readability.

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