Vial filling system for sterile and nonsterile pharmaceuticals
Enhance precision in injectable drug preparation with a solution adept at handling liquid, oily, and viscous formulations while ensuring secure filling and sealing for vials, syringes, and cartridges.

Fills and Seals Syringes, Vials, and Cartridges
The Syfill from GF is a versatile and compact filling and closing machine tailored for pharmaceutical and healthcare industries. It processes nested pre-sterilized syringes, vials, and cartridges with precision, accommodating various product types including liquids, slurries, and viscous formulations. Working on an intermittent automatic mode, the Syfill is suitable for injectable end-products such as vaccine vials and insulin cartridges. It integrates seamlessly into production lines, capable of standalone operation or within a full line including debagging and delidding units. The machine offers flexible filling systems ideal for handling emulsions and freeze-dried products. With a robust design optimized for pharmaceutical processing, it supports operational efficiency and GMP compliance. The Syfill also provides customization options to meet specific operational needs, complemented by engineering support for integration into existing systems.
Benefits
- Enhances production efficiency with precise filling and closing capabilities for injectables.
- Reduces operational costs with scalable integration into existing production lines.
- Minimizes contamination risk with processing of nested pre-sterilized containers.
- Meets stringent pharmaceutical standards with GMP-compliant operations.
- Flexibly adapts to various liquid formulations, enhancing product versatility.
- Applications
- Liquid formulations,Suspensions,Prescription applications,Viscous formulations,Injectables,Oily formulations
- End products
- Ophthalmic solution vials,Antibody syringes,Antibiotic syringes,Biological injectable vials,Iv medication vials,Pain management drug cartridges,Hormone replacement syringes,Insulin cartridges,Vaccine vials,Chemotherapy drug vials
- Steps before
- Debagging,Delidding
- Steps after
- Rod insertion,Labeling,De-nesting
- Input ingredients
- nested pre-sterilized syringes,nested pre-sterilized vials,nested pre-sterilized cartridges,liquid products,freeze-dried products,suspension products,emulsion products,oil-based products
- Output ingredients
- filled syringes,filled vials,filled cartridges,packaged syringes,packaged vials,packaged cartridges
- Market info
- GF (Coesia Group) is renowned for advanced packaging and automation solutions, specializing in engineered-to-order equipment that enhances productivity and efficiency across industries, including pharmaceuticals, consumer goods, and food and beverage.
- Operating mode
- Intermittent
- Filling systems compatibility
- Liquid,Freeze-dried,Suspension,Emulsion,Oil-based
- Installation type
- Stand-alone or complete line
- Packaging closing options
- Plunger or rubber stopper
- Packaging type
- Cartridges,Syringes,Vials
- Product state compatibility
- Liquid,Oily,Viscous,Suspension
- Max air pressure
- 8 bar
- Operating noise level
- 75 dB
- Working mechanism
- Intermittent
- Integrated steps
- Filling and closing
- Batch vs. continuous operation
- Batch
- Cleaning method
- Manual / CIP (assumed)
- Scalability
- High (modular as needed)
- Automation level
- Automatic
- Integration possibilities
- Standalone or part of a complete line
- Filling systems capability
- Liquid,freeze-dried,suspension,emulsion,oil-based
- Packaging closing type
- Plunger or rubber stopper