Vial filling system for sterile and nonsterile pharmaceuticals

Enhance precision in injectable drug preparation with a solution adept at handling liquid, oily, and viscous formulations while ensuring secure filling and sealing for vials, syringes, and cartridges.

Fills and Seals Syringes, Vials, and Cartridges

The Syfill from GF is a versatile and compact filling and closing machine tailored for pharmaceutical and healthcare industries. It processes nested pre-sterilized syringes, vials, and cartridges with precision, accommodating various product types including liquids, slurries, and viscous formulations. Working on an intermittent automatic mode, the Syfill is suitable for injectable end-products such as vaccine vials and insulin cartridges. It integrates seamlessly into production lines, capable of standalone operation or within a full line including debagging and delidding units. The machine offers flexible filling systems ideal for handling emulsions and freeze-dried products. With a robust design optimized for pharmaceutical processing, it supports operational efficiency and GMP compliance. The Syfill also provides customization options to meet specific operational needs, complemented by engineering support for integration into existing systems.

Benefits

  • Enhances production efficiency with precise filling and closing capabilities for injectables.
  • Reduces operational costs with scalable integration into existing production lines.
  • Minimizes contamination risk with processing of nested pre-sterilized containers.
  • Meets stringent pharmaceutical standards with GMP-compliant operations.
  • Flexibly adapts to various liquid formulations, enhancing product versatility.

General


Applications
Liquid formulations,Suspensions,Prescription applications,Viscous formulations,Injectables,Oily formulations
End products
Ophthalmic solution vials,Antibody syringes,Antibiotic syringes,Biological injectable vials,Iv medication vials,Pain management drug cartridges,Hormone replacement syringes,Insulin cartridges,Vaccine vials,Chemotherapy drug vials
Steps before
Debagging,Delidding
Steps after
Rod insertion,Labeling,De-nesting
Input ingredients
nested pre-sterilized syringes,nested pre-sterilized vials,nested pre-sterilized cartridges,liquid products,freeze-dried products,suspension products,emulsion products,oil-based products
Output ingredients
filled syringes,filled vials,filled cartridges,packaged syringes,packaged vials,packaged cartridges
Market info
GF (Coesia Group) is renowned for advanced packaging and automation solutions, specializing in engineered-to-order equipment that enhances productivity and efficiency across industries, including pharmaceuticals, consumer goods, and food and beverage.

Technical Specifications


Operating mode
Intermittent
Filling systems compatibility
Liquid,Freeze-dried,Suspension,Emulsion,Oil-based
Installation type
Stand-alone or complete line
Packaging closing options
Plunger or rubber stopper
Packaging type
Cartridges,Syringes,Vials
Product state compatibility
Liquid,Oily,Viscous,Suspension
Max air pressure
8 bar
Operating noise level
75 dB

Operating Characteristics


Working mechanism
Intermittent
Integrated steps
Filling and closing
Batch vs. continuous operation
Batch
Cleaning method
Manual / CIP (assumed)
Scalability
High (modular as needed)
Automation level
Automatic

Custom Options


Integration possibilities
Standalone or part of a complete line
Filling systems capability
Liquid,freeze-dried,suspension,emulsion,oil-based
Packaging closing type
Plunger or rubber stopper