Injectables Equipment

Find innovative production technology for making injectables and connect directly with world-leading specialists.

Injectables
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Parenteral preparations refer to drugs using non-oral means of administration. Injectables, such as needles and syringes, are used to deliver a drug into the systemic circulation directly in the veins, muscles, under the skin, or in the tissue. These parenteral formulations are pharmaceutical dosage forms that have strict regulations on being sterile, pyrogen-free, and free from visible particulate matter including reconstituted sterile powders. Solutions, suspensions, emulsions, and gels with APIs intended for administration by injection are usually supplied in vials, ampoules, pre-filled syringes, or pens to facilitate ease of use.

Which injectables technology do you need?

Linear vial washer for injectable drug containers

Linear vial washer for injectable drug containers

In pharmaceutical manufacturing, maintaining sterility and cleanliness o…

Vial filling solution for injectable solutions

In pharmaceutical manufacturing, precise filling of liquid, oily, or suspens…

Sterile and nonsterile vial filling system for injectables

Sterile and nonsterile vial filling system for injectables

In pharmaceutical manufacturing, the precise, contamination-fr…

Injection stretch blow moulding line for pharmaceutical solutions

Injection stretch blow moulding line for pharmaceutical solutions

In the pharmaceutical and healthcare industry, the nee…

Sterility test isolator for injectables and sterile powders

Sterility test isolator for injectables and sterile powders

In the bio-pharmaceutical industry, ensuring sterility of pro…

Table top sterile filling line for injectables

Table top sterile filling line for injectables

Where a compact solution is required for filling vials for the injectables m…

Start-up sterile filling line for injectables

Start-up sterile filling line for injectables

For smaller-scale production of vials and syringes for the injectables market…

Sterile filling line for injectables

Sterile filling line for injectables

Sterile filling of liquids and powders for the pharmaceutical and cosmetic industries r…

High-speed aseptic injectable vial filling machine

High-speed aseptic injectable vial filling machine

Fill up to 24,000 vials per hour with pharmaceutical powders or liquids…

Pharma manufacturing process vessels

Pharma manufacturing process vessels

Manufacturing sterile injectable drugs demands precision and compliance with stringent …

Rotary filling system for Rtu vials in pharma production

Rotary filling system for Rtu vials in pharma production

In clinical and early-stage pharmaceutical production, there is a…

Automatic visual inspection for sterile preparations

Automatic visual inspection for sterile preparations

In the pharmaceutical industry, ensuring the quality and purity of st…

Sterile liquid preparation system for pharmaceutical use

Sterile liquid preparation system for pharmaceutical use

In pharmaceutical production, maintaining aseptic conditions duri…

Aseptic small / medium batch filling and closing system

Aseptic small / medium batch filling and closing system

In clinical and commercial pharmaceutical manufacturing, maintaini…

Agitator bead mill for API

Agitator bead mill for API

To achieve precisely defined API properties and safe and reproducible production, rigorous impleme…

High-frequency vibratory mixer

High-frequency vibratory mixer

Mixing liquid products by stirring method generates heat from friction and shear forces. This …

Entry-level filler for large-volume parenterals

Entry-level filler for large-volume parenterals

Large volume parenterals are unit-dose containers that are larger than 100m…

API powders storage bottle

API powders storage bottle

Users who prefer rigid storage over single-use pharma charge bags, require lightweight solutions f…

Pharmaceutical pure steam generator

Pharmaceutical pure steam generator

Dry, saturated steam can be used to sterilise pharmaceutical manufacturing equipment, an…

Water distillation system

Water distillation system

Water used in pharmaceutical processes must meet high standards of regulatory bodies. These include…

Vapor compression distiller

Vapor compression distiller

Water for injections must be of highest achievable quality to eliminate the possibility of contam…

Reverse Osmosis water filtration system

Reverse Osmosis water filtration system

Reverse osmosis uses a partially permeable membrane to remove undesirable molecules,…

Packaging machine for syringes in trays

Packaging machine for syringes in trays

Pre-dosed syringes are rapidly becoming the method of choice for the delivery of inj…

Monobloc small volume liquid filler

Monobloc small volume liquid filler

These intermittent motion monobloc machines are designed for filling various liquids int…

Compact horizontal laminar flow bench

Compact horizontal laminar flow bench

HEPA filtered horizontal laminar airflow (cross-flow) creates an optimized free space …

Horizontal laminar flow benches

Horizontal laminar flow benches

HEPA filtered horizontal laminar airflow (crossflow) creates an ISO 14644-1 (Class 5) work ar…

Purified water systems

Purified water systems

Highly Purified water is used in the preparation of medicinal products where bacterial endotoxins need …

Pure steam generator

Pure steam generator

Pure steam is mainly used in the pharmaceutical industry and in biotechnology for sterilization, water fo…

Liquid dosing and assembly platform for pharmaceutical products

Liquid dosing and assembly platform for pharmaceutical products

In pharmaceutical production, precise dosing and assembly…

Cost-effective rigid-wall isolator for aseptic applications

Cost-effective rigid-wall isolator for aseptic applications

When conducting aseptic processes such as sterile testing, sm…

Ra-223 dichloride production and dispensing suite

Ra-223 dichloride production and dispensing suite

In radiopharmaceutical production, handling materials like Radium-223 di…

Aseptic small batch filling and closing system

Aseptic small batch filling and closing system

Ensuring the sterility of drug products during small batch production is cru…

3D powder mixer for active pharmaceutical ingredients

3D powder mixer for active pharmaceutical ingredients

Proper mixing and homogenization are essential to achieve a reliable…

Flexible laboratory bead mill for vaccines

Flexible laboratory bead mill for vaccines

For precise, efficient, and reproducible cell disruption, optimization of proces…

GMP dispersing machine for liquid formulations

GMP dispersing machine for liquid formulations

Multi-staged rotor/stator mixers generate the high shear forces required to …

Modular assembly line for healthcare products

Modular assembly line for healthcare products

Assembly setups need to be constantly rethought and reconfigured to adapt qui…

Stories about injectables

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Manufacturing parenteral formulations


Fragile molecules such as protein formulations would be destroyed using the alimentary canal and are therefore administered by injection. When making injectable formulations the drugs are stored in liquid or, if unstable at higher temperatures, lyophilized form. To ensure a stable active medium during storage and make the preparation isotonic with blood, liquid formulations combine active ingredients with a minimum amount of excipients such as solvents, solubilizers, suspending, and buffering agents, and antimicrobial preservatives.


Water for injections(WFI) is used as the vehicle for aqueous injections. For non-aqueous injections, fixed oils of vegetable origin are used as vehicles. Water for Injection is used in the preparation of medicines as a vehicle and sterilized water for injection is used when solving or diluting substances or preparations before use. WFI is obtained by distillation or reverse osmosis and meets all chemical requirements for PW (Purified Water) with an additional bacterial endotoxin parameter.


Lyophilized drugs allow storage at higher temperatures after freeze-drying is used to remove water from a liquid drug and create a solid powder or cake. In protein formulations, stabilizers are added to replace the water and preserve the molecule structure. Before administration, a lyophilized drug is reconstituted by combining a liquid diluent with the freeze-dried powder and mixing before injected into the body.


Vaccine development and production technology

Applikon Biotechnology is specialized in human vaccine production systems, as well as in systems for the production of therapeutic agents using both cell culture and microbial cultures.

Their advanced bioreactor systems can be used from the initial screening stage up to full-scale production using the same platform to minimize scale-up risks and guarantee a short time to market in product development.

Visual and high voltage leak detection (HVLD) inspection

Inspection of sealed glass vessels for contaminants, correct fill volume, sealing, and for example tip-cap effects or black spot particles. How convenient to cover all quality inspection requirements at once?

CMP Pharma’s NIKE-LT’s recirculation feature allows re-inspection following rejection by only one or two cameras (user selectable) which brings false rejection rates down reducing unnecessary wastage.

Sterile filling and packing of injectables


Sterile dosage forms must be free from any microorganisms, dust, fibers, and foreign particles, and should be isotonic. Although standards and legislation may differ worldwide there are several regulations to ensure the product or safe and effective new and generic drugs on the market such as USP/JP/EP standards and Current Good Manufacturing Processes (GMP) compliance.


Small-volume parenteral solutions (SVPs) are injections provided in containers 100 ml or less and can be designed for single and for multiple uses.  A large volume parenteral (LVP) is a single-use unit dose container of greater than 100ml designed to carry fluids, calories, and electrolytes.


For light-sensitive substances, colored glass containers such as vials or ampoules are used. If possible containers are made transparent for easier visual inspection. Containers are made, as far as possible, from material that is sufficiently transparent to permit visual inspection. Closures are equipped with a firm seal to prevent the entry of microorganisms and other contaminants while permitting the withdrawal of a part of the whole of the contents without removal of the closure. Closures for multidose containers are sufficiently elastic to allow the puncture to reseal when the needle is withdrawn.


Equipment for making injectables in action

Applikon next generation in microbioreactors

Vial filling line

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