Automated sample preparation workstation for content uniformity testing

Streamline your laboratory workflows with automated equipment that minimizes manual intervention, maximizes resource allocation, and enhances accuracy in critical sample preparation tasks, from weighing to analysis, while ensuring utmost safety and efficiency.

Automates Sample Weighing, Extraction, and Filtration

The TPW Automated Sample Preparation Workstation from SOTAX stands out with its ability to efficiently automate tasks such as weighing, extraction, and dilution, essential for high-throughput laboratories. It employs a high-shear homogenizer to ensure consistent wet grinding, crucial for reproducible sample extraction across varied dosage forms, from tablets and API powders to injectable suspensions and gels. The integrated fluid metering pump facilitates precise filtration and dilution, accommodating up to 1:100,000 dilutions. With built-in HPLC and UV spectrophotometer interfaces, it enables seamless integration into analytical workflows. Designed for pharmaceutical, biotech, and chemical industries, the TPW improves safety and efficiency by reducing solvent use and minimizing hazardous exposure. Constructed from materials suitable for corrosive environments, it supports both efficiency and compliance with industry standards, streamlining cleaning and maintenance with programmable cycles. The TPW also offers customization for specific laboratory needs, supported by SOTAX’s expert engineering teams.

Benefits

  • Enhances laboratory efficiency by automating repetitive sample preparation tasks, freeing personnel for critical analysis.
  • Increases precision and consistency in sample processing, reducing the risk of human error.
  • Minimizes solvent usage and hazardous waste production, optimizing operational sustainability.
  • Ensures integration with analytical instruments like HPLC and UV spectrophotometers for streamlined analysis.
  • Customizable for diverse applications, from pharmaceutical tablets to injectable suspensions, supporting broad laboratory needs.

General


Applications
Medical devices,Gels,Pellets,Granules,Microspheres,Catalysts,Stents,Food,Nano suspensions,Fine chemicals,Coated lenses,Soft-gelatin capsules,Implants,Animal health,Capsules,Powders,Washtabs,Transdermal patches,Creams,Suppositories,Semi-solids,Bottles with screw caps,Apis,Tablets,Injectable suspensions
End products
Anti-inflammatory gel,Catalytic converters,Fertilizer pellets,Protein powder,Hydrocortisone cream,Veterinary vaccines,Vitamin granules,Insulin syringes,Glycerin suppositories,Dishwasher tablets,Nanoparticle suspensions for cancer treatment,Anti-reflective coated lenses,Ibuprofen tablets,Omega-3 fish oil capsules,Nicotine patches,Fish oil soft-gel capsules,Nutritional pet food,Influenza vaccine microspheres,Paracetamol active pharmaceutical ingredient (api),Coronary artery stents,Knee implants,Epinephrine injectable solution,Vitamin bottles with screw caps,Lithium battery electrolytes
Steps before
Sample weighing,Sample averaging,Sample collection
Steps after
Data analysis,Reporting,Notebook documentation,Sample storage,On-line HPLC analysis,On-line UV analysis
Input ingredients
tablets,capsules,pellets,API's,powders,granules,soft-gelatin capsules,suppositories,medical devices,stents,implants,microspheres,nano suspensions,injectable suspensions,semi-solids,gels,creams,transdermal patches,washtabs,fine chemicals,catalysts,food,animal health products,coated lenses,bottles with screw caps
Output ingredients
extracted samples,diluted samples,HPLC vials,sequences for Empower™,prepared sample records,analysis-ready samples
Market info
Sotax AG is renowned for its expertise in manufacturing high-quality pharmaceutical testing equipment, including dissolution testing systems, and has a strong reputation for reliability, precision, and innovation in laboratory and industrial applications.

Technical Specifications


Automation
Automated Sample Preparation
Extraction volume
20 – 520 mL
Assay and content/blend uniformity
Up to 100 samples
Filtration type
Volumetric,confirmed gravimetrically
Dilution ratio
Up to 1
Sample types
Solid oral dosage forms
Cleaning method
Programmable between samples
Video monitoring
VideoLink™ with specific event triggers
HPLC integration
Built-in injector for on-line analysis
Sample storage
Sealed HPLC vials
Software interface
Waters Empower™ Interface
Homogenizer type
High-shear
Error handling capabilities
Advanced error handling
Data management software
TPWsoft
Process control
TPWsoft – Software for data capture and reporting

Operating Characteristics


Working mechanism
Automated sample weighing,extraction,filtration,and dilution
Integrated steps
Weighing,extraction,filtration,dilution,and transfer
CIP/SIP principles
Programmed cleaning between samples
Batch vs. continuous operation
Batch
Automation level
Automated / Manual
Error handling capabilities
Advanced error handling
Audit trail
Comprehensive record of preparation process
Video monitoring
VideoLink™ with event-triggered cameras
Homogenization
High-shear homogenizer
Cycle time reduction
Enhanced for efficiency
Solvent usage
Reduced
Safety
Improved analyst safety by reduced exposure

Material Compatibility


Density/particle size
0.5–2.5 g/cm³ / 50–1000 µm

Product type Characteristics


Sample type compatibility
Tablets,capsules,powders,granules

Physical Characteristics


Footprint
Compact
Sample Capacity
Up to 100 samples
Initial Extraction Volume
20 – 520 mL
Discharge Method
Automated Transfer to Analysis Devices
Control Panel Type
TPWsoft Interface
Video Monitoring
VideoLink™
High-shear Homogenizer
Included

Custom Options


Control panel type
Touchscreen HMI
Integration possibilities
Waters Empower™ Interface
Video monitoring
VideoLink™ with event-triggered cameras
Automation level
Fully automated sample preparation
Sample transfer methods
HPLC injection,UV autosampler