Capsule Making Equipment
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Automatic capsule filling machines
In pharmaceutical manufacturing, accurate and efficient capsule filling is crucial for ma…
Integrated counting system for tablets and capsules
In pharmaceutical production, ensuring accurate and efficient counting…
Electronic tablet counter for tablets and capsules
In pharmaceutical manufacturing, precise counting of tablets and capsul…
Table top tablet and capsule counter
In pharmaceutical production, accurately counting tablets and capsules is essential to …
Capsule selection and feeding unit
In pharmaceutical manufacturing, ensuring that only high-quality capsules are processed i…
Precision weight-checking for pharmaceutical capsules
Ensuring accurate weight control in pharmaceutical production is cru…
Capsule filler for pharmaceutical applications
In the pharmaceutical industry, ensuring precise and efficient dosing of cap…
Table-top capsule filler for micro-dosing
In pharmaceutical research and development, precise micro-dosing and solid produc…
Integrated counting system for tablet and capsule bottling
Pharmaceutical manufacturing often demands precise and efficie…
Capsule banding system for tamper-evident sealing
In the pharmaceutical industry, ensuring the integrity of capsules fille…
Blister packaging system for tablets and capsules
In pharmaceutical manufacturing, medium-sized production batches often r…
Capsule filler for multi-product dosing
In pharmaceutical production, precise and flexible capsule filling is crucial for ma…
Capsule filling and sealing system for coffee production
In the coffee production industry, precise and efficient filling …
Capsule filling and sealing system for coffee products
For medium production volumes in coffee processing, achieving high …
Capsule filling and sealing for lab purposes
For researchers and lab technicians working on small-scale production of coffe…
Capsule filling and sealing system for coffee
In many coffee production facilities, precision in dosing and sealing is esse…
Capsule cartoning system for coffee and tea
In high-volume production settings, managing the packaging of oriented capsules…
Cartoning system for coffee capsules
When handling high-volume packaging for coffee products, efficiency and space optimizat…
Capsule cartoning for coffee and tea products
In the coffee and tea industry, packaging efficiency and maintaining product …
High-speed capsule cartoning solution
When handling capsule packaging at high production speeds, maintaining gentle handling…
In-process weighing system for capsules and tablets
During the production of pharmaceutical capsules and tablets, maintain…
Weighing system for 100% inspection of capsules and tablets
In pharmaceutical manufacturing, ensuring product quality thr…
High-speed capsule weighing system for quality assurance
In pharmaceutical production, accurately weighing capsules at hig…
Versatile capsule filler for pharmaceuticals
In the pharmaceutical industry, high-precision and flexibility in capsule prod…
Containment capsule filling system for lab and small batch production
In pharmaceutical research and development, testin…
Capsule filling system for powder, pellets, and tablets
In large-scale pharmaceutical production, ensuring efficient and a…
High-containment capsule dosing and filling system
In pharmaceutical manufacturing, handling highly active substances dema…
Commercial capsule filling for small scale production
In pharmaceutical manufacturing, efficiently filling capsules with p…
Filled capsule conveyor system for pharmaceutical production
In pharmaceutical manufacturing, the delicate transfer of fi…
Empty capsule transfer system
In pharmaceutical manufacturing, maintaining a continuous supply of empty capsules to the filli…
Capsule conveyors for gentle capsule transfer
In pharmaceutical manufacturing, keeping the capsule filling machines continu…
Integrated bottling center for pharmaceutical tablets and capsules
In pharmaceutical manufacturing, accurate and reliabl…
Linear tablet and capsule counter
In pharmaceutical manufacturing, ensuring each bottle contains the exact count of tablets …
Counting system for tablets and capsules
In pharmaceutical and supplement manufacturing, accurate and efficient counting of …
High speed strip packaging for tablets and capsules
In pharmaceutical manufacturing, ensuring efficient and fast packaging…
High-speed strip packaging for tablets and capsules
When producing pharmaceuticals, the need for efficient, high-speed pac…
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Automatic capsule filling machines
In pharmaceutical manufacturing, accurate and efficient capsule filling is crucial for ma…
Integrated counting system for tablets and capsules
In pharmaceutical production, ensuring accurate and efficient counting…
Electronic tablet counter for tablets and capsules
In pharmaceutical manufacturing, precise counting of tablets and capsul…
Table top tablet and capsule counter
In pharmaceutical production, accurately counting tablets and capsules is essential to …
Capsule selection and feeding unit
In pharmaceutical manufacturing, ensuring that only high-quality capsules are processed i…
Precision weight-checking for pharmaceutical capsules
Ensuring accurate weight control in pharmaceutical production is cru…
Capsule filler for pharmaceutical applications
In the pharmaceutical industry, ensuring precise and efficient dosing of cap…
Table-top capsule filler for micro-dosing
In pharmaceutical research and development, precise micro-dosing and solid produc…
Integrated counting system for tablet and capsule bottling
Pharmaceutical manufacturing often demands precise and efficie…
Capsule banding system for tamper-evident sealing
In the pharmaceutical industry, ensuring the integrity of capsules fille…
Blister packaging system for tablets and capsules
In pharmaceutical manufacturing, medium-sized production batches often r…
Capsule filler for multi-product dosing
In pharmaceutical production, precise and flexible capsule filling is crucial for ma…
Capsule filling and sealing system for coffee production
In the coffee production industry, precise and efficient filling …
Capsule filling and sealing system for coffee products
For medium production volumes in coffee processing, achieving high …
Capsule filling and sealing for lab purposes
For researchers and lab technicians working on small-scale production of coffe…
Capsule filling and sealing system for coffee
In many coffee production facilities, precision in dosing and sealing is esse…
Capsule cartoning system for coffee and tea
In high-volume production settings, managing the packaging of oriented capsules…
Cartoning system for coffee capsules
When handling high-volume packaging for coffee products, efficiency and space optimizat…
Capsule cartoning for coffee and tea products
In the coffee and tea industry, packaging efficiency and maintaining product …
High-speed capsule cartoning solution
When handling capsule packaging at high production speeds, maintaining gentle handling…
In-process weighing system for capsules and tablets
During the production of pharmaceutical capsules and tablets, maintain…
Weighing system for 100% inspection of capsules and tablets
In pharmaceutical manufacturing, ensuring product quality thr…
High-speed capsule weighing system for quality assurance
In pharmaceutical production, accurately weighing capsules at hig…
Versatile capsule filler for pharmaceuticals
In the pharmaceutical industry, high-precision and flexibility in capsule prod…
Containment capsule filling system for lab and small batch production
In pharmaceutical research and development, testin…
Capsule filling system for powder, pellets, and tablets
In large-scale pharmaceutical production, ensuring efficient and a…
High-containment capsule dosing and filling system
In pharmaceutical manufacturing, handling highly active substances dema…
Commercial capsule filling for small scale production
In pharmaceutical manufacturing, efficiently filling capsules with p…
Filled capsule conveyor system for pharmaceutical production
In pharmaceutical manufacturing, the delicate transfer of fi…
Empty capsule transfer system
In pharmaceutical manufacturing, maintaining a continuous supply of empty capsules to the filli…
Capsule conveyors for gentle capsule transfer
In pharmaceutical manufacturing, keeping the capsule filling machines continu…
Integrated bottling center for pharmaceutical tablets and capsules
In pharmaceutical manufacturing, accurate and reliabl…
Linear tablet and capsule counter
In pharmaceutical manufacturing, ensuring each bottle contains the exact count of tablets …
Counting system for tablets and capsules
In pharmaceutical and supplement manufacturing, accurate and efficient counting of …
High speed strip packaging for tablets and capsules
In pharmaceutical manufacturing, ensuring efficient and fast packaging…
High-speed strip packaging for tablets and capsules
When producing pharmaceuticals, the need for efficient, high-speed pac…
Encapsulation equipment for microbeads and microcapsules
In research and development applications, precise encapsulation o…
Soft gel encapsulation system
In the production of pharmaceuticals, cosmetics, and health supplements, precise encapsulation …
Capsule filling system for pharmaceutical production
In the pharmaceutical industry, ensuring precise dosing and minimizin…
Capsule filling solution for small to medium batch sizes
When producing pharmaceutical or nutraceutical capsules, achievin…
Tablet and capsule visual inspection system
In pharmaceutical and nutraceutical production, identifying and rejecting table…
Capsule filler for high-speed, dust-free capsule production
In pharmaceutical manufacturing, accurate and efficient capsu…
High-speed capsule filler for large batch production
In pharmaceutical and nutraceutical manufacturing, achieving high yie…
Containment capsule filler for highly potent drugs
In pharmaceutical manufacturing, handling highly potent active pharmace…
Liquid filling system for hard capsules
In the pharmaceutical industry, producing liquid-filled hard capsules with precision…
Liquid capsule filling for r&d and pilot-scale production
In R&D or pilot-scale production, ensuring the integrity of…
Capsule band sealer for liquid-filled hard capsules
In pharmaceutical manufacturing, ensuring accurate and secure sealing …
Rotary blister packaging for tablets and capsules
In pharmaceutical manufacturing, the need for efficient and high-quality…
Metal contamination detection for tablets and capsules
In pharmaceutical manufacturing, ensuring product purity is paramou…
Capsule sorter elevator for encapsulation processes
In pharmaceutical and nutraceutical manufacturing, preventing stoppage…
Filled capsule elevator for seamless process integration
In pharmaceutical manufacturing, transferring capsules between st…
Empty capsule sorting system for pharmaceutical manufacturing
In pharmaceutical manufacturing, ensuring the quality and u…
Capsule de-dusting and polishing system
In capsule production, excessive powder on capsule shells can lead to compromised pr…
Automatic capsule checkweigher for statistical weight control
In pharmaceutical and nutraceutical manufacturing, maintain…
Vision inspection system for tablets and capsules
Pharmaceuticals and healthcare product manufacturers dealing with oral s…
Automatic medical forming and sealing blister machine for packing capsules and tablets
Product safety is very importan…
Cold forming aluminum blister machine for capsules
Aluminum blisters are mainly used for packaging products that are sensi…
Effective Visual Inspection System for Capsules
The attribute of capsule packing is a critical parameter that controls the …
Metal detector for tablets and capsules
Identification of metallic contaminants is a vital part of pharmaceutical quality co…
Electronic capsule counter
For lab work or small batch production, hand counting of solid doses into dispensing containers is…
Semi-automatic capsule filler
Hard gelatin capsules are a popular format for delivering a wide variety of pharmaceutical dose…
Automatic capsule loader
Capsules are a popular method of dosage delivery for a wide range of compounds. For anything other th…
Laboratory scale soft gelatin capsule machine
Softgel (or soft gelatin) capsules are a very popular method for providing or…
Automatic soft gelatin capsule machines
Soft gelatin (or softgel) capsules have become a popular mode of oral liquid dosing …
Softgel capsules polisher
The final stage in high quality softgel (or soft gelatin) capsule production is the capsule polish.…
Waste minimization weight sorter for tablets & capsules
For medium scale production, you can improve line efficiency and r…
High capacity weight sorter for tablets & capsules
By employing a weight sorter that is fully flexible and able to han…
Capsule checkweigher
The production of pharmaceutical capsules requires that individual doses are checked for accuracy. In a p…
High capacity capsule filler
In the highest volume pharmaceutical production environments, capsule filling needs to be extrem…
Scale up capsule filler
For higher production volumes of pharmaceutical capsules, speed, accuracy and reliability of productio…
Entry level capsule filler
For the production of pharmaceutical doses in capsule form complete accuracy of fill is paramount.…
Microencapsulation system for your drug delivery system
Whether you want to improve the stability of nutrients, protect an…
Benchtop weight sorter for tablets & capsules
For laboratory pharmaceutical R&D work or use in clinical trials, a …
Versatile weight sorter for tablets & capsules
Saving costs and improved production efficiencies are possible by optin…
Industrial capsule checkweigher
Pharmaceutical manufacturing demands the highest quality standards and completely consistent …
Laboratory capsule filler for liquid solutions
A recent important change in the industry is the trend toward providing liqu…
Automatic capsule filler for liquid solutions
Use of liquid filled hard capsules is increasingly popular with today's pharm…
Automatic laboratory capsule filler
Innovators in the highly regulated and highly dynamic pharmaceutical market place need e…
Contained capsule filler
For pharmaceutical formulations that are highly active specialized capsule filling equipment is often…
Automatic capsule filler
Capsule filling should be a worry-step in pharmaceutical and nutraceutical manufacturing. The right …
High-yield capsule filler
Pharmaceutical manufacturers require maximum yield from their encapsulation process for efficient p…
Easy to validate capsule filler
Staying competitive in today's highly dynamic and highly regulated pharmaceutical production …
Checkweigher for capsules
The new interactive indicator unit allows for even easier use. High-rigidity weighcells have been p…
R&D electronic counter for capsules and tablets
This machine has been designed to offer an ever-precise and reliable count …
R&D hard gelatin capsule sealing machine
When encapsulating products at temperatures up to + 80°C, these tend to solidify at…
R&D capsule orientater
A semi-automatic orienter for capsules with an output speed up to 6000 capsules.
R&D semi-automatic capsule filler
Semi-automatic filling machine suitable to open, fill and close empty hard gelatin capsule…
R&D automatic capsule filler
Automatic capsule filling machine for powders, pellets, tablets, mini-tablets, capsule in capsul…
Vertical dosing and filling solution for confectionery packaging
In the confectionery industry, handling various product …
Desiccant inserter for pharmaceutical bottles
In pharmaceutical packaging, maintaining product integrity and extending shel…
Thermoforming solution for clinical trials
In clinical trials and short production runs, precision in packaging is paramoun…
High-speed blister packaging with integrated cartoner
In pharmaceutical production, there is often a need to package table…
Pharmaceutical metal detectors
In the pharmaceutical industry, ensuring that products are free from any metal contaminants is…
Powder dosing for lab and galenics
In pharmaceutical development, accurately dosing minimal quantities of powder is crucial.…
Powder dosing machine for laboratory applications
In laboratory settings, precise and flexible dosing of powders is crucia…
Powder dosing system for development and small batches
In the pharmaceutical industry, precise dosing of powders is critic…
Semi-automatic powder dosing system
In pharmaceutical development and galenics, precise dosing of small quantities of powder…
Closed loop granulator for pharmaceutical production
Factories producing pharmaceutical tablets or capsules often face cha…
Consumables for elemental analyzers
Precision analysis of various elements in organic and inorganic samples necessitates rel…
In-motion bottle filling system for pharmaceuticals
In pharmaceutical manufacturing, filling bottles with precise quantiti…
Weight filler for small batches in explosive areas
In industries such as pharmaceuticals, foods, and chemicals, accurately…
Tablet counting solution for pharmaceutical industry
In pharmaceutical manufacturing, accurate counting of tablets, dragee…
Self-adhesive labeling system for bottles
In bottling lines, ensuring precision and high-quality labeling while minimizing …
High speed blister packaging for pharmaceuticals
In pharmaceutical manufacturing, efficient and reliable packaging of pills…
Small batch tablet and pellet coating solution
In formulation development, working with small batches demands precise and r…
Coffee processing system for integrated coffee production
In coffee manufacturing, achieving consistent flavor and bean q…
Bead mill for nano-preparation grinding
In the pharmaceutical and coating industries, achieving precise particle size and di…
Softgel pre-dryer tumbler system
In the manufacturing process of softgel capsules, achieving optimal shape and seam while rem…
Vibration batch dryer for difficult solids
When dealing with solids that are difficult to handle, such as those that stick,…
Pharmaceutical roller compactor
In pharmaceutical manufacturing, small batch and special product production often face challe…
Pharmaceutical roller compaction solution
In pharmaceutical manufacturing, ensuring consistent particle size for tablets an…
Dry granulation technology
In pharmaceutical, chemical, and food industries, the need for improved powder processing methods …
Blister packaging for solid dosage forms
Packaging solid dosage forms such as tablets, hard capsules, and soft gelatine caps…
Containment blister packaging for highly potent Apis
In pharmaceutical manufacturing, especially when dealing with highly …
Tabletop blister packaging for clinical trials
Clinical trials and feasibility studies demand precise and dependable bliste…
Flat-forming blister packager for small production batches
When packaging sensitive products like tablets or capsules in …
Flat-sealing continuous-motion blister packaging solution
In the pharmaceutical packaging industry, ensuring product inte…
Flat forming and sealing blister packaging solution
Pharmaceutical companies often require reliable and efficient packagin…
Automated powder and pellet product conveying system
Handling and transferring powders and pellets in pharmaceutical manuf…
Semi-automatic de-blistering solution for Pvc and alu blister packs
In pharmaceutical manufacturing, recovering capsules…
Desiccant inserter for pharmaceutical containers
In the pharmaceutical and nutraceutical industries, maintaining product qu…
Inspection system for tablets chemical composition
The packaging of pharmaceuticals and oral solid products such as tablet…
Blister inspection system
The pharma and healthcare industries widely use blister thermoforming machines to package a variety…
Semi-automatic forming and sealing blister machine
As a manufacturer of medical device, the packaging is a critical factor…
Contained Visual Inspection System
In the medicine industry, it is important to ensure there are no defects in tablets or ca…
High speed bottle filler with inspection
Medicines in tablet, capsule, or soft gel forms undergo various processes before re…
High Speed Visual Inspection System for Tablets
In order to ensure quality and standard specifications of tablets, capsules…
Lifter and De-duster for Tablets
The use of several different tools for lifting, de-dusting, and polishing in the pharmaceuti…
Particle analysation monitor
Products like granules, tablets and capsules require inspection at numerous steps in the product…
Tablet counting machine
Production of pharmaceutical solid dosage forms usually require complete accuracy, flexibility, and co…
Automatic filling line for solid doses
For medium-scale production of solid doses such as tablets, capsules, and softgels th…
Softgel drying tunnel
Softgel capsules require a controlled secondary drying to reduce water content in the capsule to levels …
Continuous in-line softgel drying system
High output softgel (or soft gelatin) capsule encapsulating machines can operate be…
Softgel tumble dryer
Softgel (or soft gelatin) capsules are a very popular means of delivering oral doses in the pharmaceutica…
Gelatin melters and tanks
When producing high quality softgels its important that the gelatin base is processed and stored co…
Compact blister machine
A compact blister machine ideal for packing tablets, capsules, ampoules and syringes and other applica…
Laboratory film coating system for development and clinical batches
In laboratories and smaller scale production environ…
Advanced friability and abrasion testing solution
Ensuring consistent quality and durability of tablets often involves rig…
Slat-type counting solution for pharmaceutical applications
In pharmaceutical production, ensuring accurate pill counting…
Leak detection unit for coffee pods
In the coffee pod manufacturing industry, ensuring the seal quality of finished pods is …
Serialization equipment for cases
Serialization is a multi-stage process that includes printing, inspection, and labeling. B…
Individual item serialization equipment
Traceability is critical to quality assurance in the pharmaceutical sector. But seri…
Flat carton coding machine
The coding process is an essential step in the production line as it can provide trusted supply ch…
Software to differentiate between the original pharmaceutical barcode and a reprint
Counterfeit products pose a seriou…
Serialized labels inspection and printing station
Labels are a key component in pharmaceutical packaging lines as they inc…
Serialization tracking system
To accommodate different products of varied sizes, the pharmaceutical industry requires handlin…
Serialization and aggregation system
Manufacturers from the pharmaceutical industry require a variety of cartons, cases and …
Flat carton serialization station
The packaging lines in the pharmaceutical industry handle several flat cartons. Manual pac…
Clinical trial lab sealer for a laminar airflow bench
When running small production for clinical trials, stability studies…
Granulation line for pharmaceutical solid dosage forms
Granulation is a common technique in production of pharmaceutical s…
Industrial high shear mixer granulator for drug formation
It is rather difficult to successfully produce a pharmaceutical…
Fluid bed dryer for pharmaceutical solid dosage form
Fluid bed drying is a pharmaceutical process carried out to reduce th…
Dessicant inserting machine
Desiccant canisters play an important role in the pharmaceutical and nutraceutical industries. Th…
Pharmaceutical bottle unscrambler
Pharmaceutical packaging industry requires the ability to quickly manage the process yet a…
Suppository filling machine
Small-to-medium scale production of suppositories using pre-formed shells can be slow where manua…
Semi-automatic powder dosing machine
Powders or granules are common dose types used in many pharmaceutical and nutraceutical…
Bulk chamber washer
The production of cosmetics, nutraceuticals or unregulated pharmaceuticals often requires the cleaning and…
Entry-level chamber washer
When cleaning smaller products contacting filling or compressing components used in the production…
Loading basket for GMP washer
To ensure perfect cleaning of contact parts they must be placed in the GMP washer in such a way…
Starch-free depositor for hard candy
Forming hard candies requires careful handling of syrups in order to avoid quality issu…
Thin-film cooker for confectionery products
Producing excellent confectionery products requires high quality cooking. Tradi…
Dissolver of confectionery syrups
Many high quality confectionery products require a dissolved syrup as their starting point…
Automatic weigher and mixer of confectionery ingredients
The production of accurately proportioned and homogenous slurries…
Granulation line of mixer and fluid bed dryer
A complete granulation line allows for the mixing and granulation of pharmace…
Fluid bed dryer for production scale
Fluidized bed drying (FBD) is a common process in the pharmaceutical industry for dryin…
Fluid bed dryer for lab scale
Fluidised bed drying (FBD) is a common process in the pharmaceutical industry for drying compou…
Fluid bed dryer and mixer for lab scale
Designed for pharmaceutical R&D, a lab-scale fluid bed dryer and mixer/granulato…
Conical mill for drug formulation
The efficient size reduction of granular powders is a key step in many pharmaceutical proc…
High-shear mixer
For the efficient mixing of larger batches of pharmaceutical compounds and high-shear mixer provides the optim…
Entry-level high-shear mixer for drug formulation
For pilot and lab-scale pharmaceutical formulations, a high-shear granul…
Laboratory dispersing machine for low-viscous masses
Laboratory mixers have not always been easy to work with. Getting al…
Ultra-fine dispersing machine for emulsions and suspensions
Producing the finest micro-emulsions and suspensions requires…
Economic dispersing machine for emulsions and suspensions
For products of medium viscosity and relatively consistent part…
Checkweigher
A check weigher that is equipped with high speed/high accuracy force balance load cell. It meets stringent accurac…
Case packer for cartons and bundles
Pack cartons and bundles into RSC (Regular Slotted Case) cases and perform functions lik…
Stretch bander
A compact wrapping machine to seal your boxes with a max speed of 50 packs per minute.
Vertical cartoner
A cartoning solution that can be operated in either continuous or intermittent mode depending on the cartoni…
Horizontal intermittent motion cartoner
User-friendly cartooning solution with an intermittent motion for a wide range of pr…
Horizontal continuous motion cartoner
An automatic cartoning machine designed for both high-speed operations and medium pack…
Entry-level blister machine
A start-up solution for contract packing and generics manufacturing with an easy-to-get upgrade a…
High-speed blister machine
If you are looking for a compact machine that produces blisters with an output of up to 700 bliste…
Negative pressure isolator
Used for products biologically hazardous, that also require minimized cross contamination.
Sterility test isolators
Designed to avoid this risk and protect the product from both the process and externally generated fa…
Half-suit tester
Designed to allow operators to perform sterility testing in an aseptic environment providing assurance of mate…
Glove tester
Testing device of the containment capability of gloves, which is as important as the other parts of the integrated…
Aseptic barrier systems
Designed for sterile product and Potent API’s either with low or high OEL requirements.
Restricted-access barrier systems
Create a physical barrier between the operator and the product. More flexible than an isol…
Stories about capsules
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Contact usWhat are you making?
Mold the shells into shape with capsule manufacturing equipment
Capsule shells are composed of the body and the cap that closes the dosage. Capsule manufacturing equipment dips a series of steel pins into a drum filled with the base material. The wet molding pins move to the drying chamber to harden as they spin on their axis to ensure even distribution.
Once the shells are formed, they are stripped off the pins. But they are not yet finished for filling. The empty capsules must first be cut to the correct length and joined in a pre-lock position, ready for encapsulation.
Pair the API with the correct shell before the capsule filling process
Encapsulation technology lines up the capsule bodies on a bed of holders. A stainless steel dosage system pours the formula in the powder tray into the shells. The caps, aligned precisely in their holding section, are ready to be lowered onto the filled capsule bodies. The fins in the body enter the slits of the cap, locking them into position.
The encapsulated ingredients directly impact shell stability. Hygroscopic materials, for example, risk cracking the gelatin capsules. Capsule filling machines must account for the properties of the dosage formula and the materials, thickness, and shelf life of the shells.
Capsule production is either an automatic, semi-automatic or manual process. Manual capsule fillers are still used in smaller production facilities. However, for making large scale pharmaceutical capsules, automation is employed to maximize output and efficiency.
Control the water content in hard gelatin capsules to balance plasticity and containment
The first hard gelatin capsules were filled with pharmaceutical formulas in powder form. But one of the advantages of encapsulation is that it offers flexibility with a range of dosage solutions, from tablets to beads to micro-capsules.
This versatility means that the gelatin shells have to deliver stability. The gelatin mix must allow enough moisture content to create elasticity without altering the properties of the encapsulated APIs.
Insufficient drying temperature leads to undesirable air pockets in soft gelatin capsules
Soft gelatin capsules, also known as softgels, are suitable for non-aqueous solutions such as oil. The active pharmaceutical ingredients are dissolved or suspended into an oil-based form.
One of the challenges in producing softgel capsules is the formation of air bubbles in the gelatin base. This happens when the capsule manufacturing equipment fails to reach the right temperature during the drying stage, and air remains trapped in the mixture. These pockets of unreleased air weaken the structure of the capsule.
HPMC capsules are more suitable hygroscopic fillings
Hypromellose emerged as the plant-sourced alternative to gelatin. But HPMC capsules are less dependent on water content, making them a better solution for hygroscopic ingredients.
However, since Hypromellose has a higher oxygen permeability, the fill ingredients need anti-oxidant additives to compensate. HPMC capsules also require oxygen-resistant packaging, such as aluminum blister configurations.
Blister packs offer greater protection for pharmaceutical capsules
The packing solution depends on the type of capsule. Vitamin or food supplement capsules may be bottled in simple containers. However, a desiccant pouch helps to absorb moisture and maintain a controlled environment.
In the case of pharmaceutical capsules, the ingredients demand safer packaging. Blister packs are more secure and are more convenient for dosage control. Complete blister packaging solutions often include coding and die-cutting systems, but simple entry-level batch machines are also available.