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HPMC capsule making equipment

The nonproprietary name for HPMC – hydroxypropyl methylcellulose – is such a mouthful that it has two abbreviations. Hypromellose is the other one. The non-ionized material offers a safe alternative to gelatin capsules, especially as most common API and excipients are suitable HPMC capsule ingredients.

Which hpmc capsules technology do you need?

Entry-level X-ray inspection system

Entry-level X-ray inspection system

Without compromising on performance, if you need an entry level x-ray inspection system …

Serialization and aggregation inspection system

Serialization and aggregation inspection system

Including serialization and aggregation inspection systems to packaging lin…

Vision inspection system for tablets and capsules

Vision inspection system for tablets and capsules

Pharmaceuticals and healthcare product manufacturers dealing with oral s…

Serialized labels inspection and printing station

Serialized labels inspection and printing station

Labels are a key component in pharmaceutical packaging lines as they inc…

Effective Visual Inspection System for Capsules

Effective Visual Inspection System for Capsules

The attribute of capsule packing is a critical parameter that controls the …

High speed bottle filler with inspection

High speed bottle filler with inspection

Medicines in tablet, capsule, or soft gel forms undergo various processes before re…

High Speed Visual Inspection System for Tablets

High Speed Visual Inspection System for Tablets

In order to ensure quality and standard specifications of tablets, capsules…

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Lifter and De-duster for Tablets

Lifter and De-duster for Tablets

The use of several different tools for lifting, de-dusting, and polishing in the pharmaceuti…

Dessicant inserting machine

Dessicant inserting machine

Desiccant canisters play an important role in the pharmaceutical and nutraceutical industries. Th…

Pharmaceutical bottle unscrambler

Pharmaceutical bottle unscrambler

Pharmaceutical packaging industry requires the ability to quickly manage the process yet a…

Tablet counting machine

Tablet counting machine

Production of pharmaceutical solid dosage forms usually require complete accuracy, flexibility, and co…

Metal detector for bottles

Metal detector for bottles

For metal contamination detection in finished products that are bottled, traditional solutions req…

Semi-automatic case packer

Semi-automatic case packer

Pharmaceutical products require complete traceability throughout the production cycle. For smaller…

Electronic capsule counter

Electronic capsule counter

For lab work or small batch production, hand counting of solid doses into dispensing containers is…

Automatic capsule loader

Automatic capsule loader

Capsules are a popular method of dosage delivery for a wide range of compounds. For anything other th…

Stand-alone aggregation station

Stand-alone aggregation station

The aggregation of pharmaceutical products for tracking purposes is already compulsory in man…

Serialization coding and labeling equipment

Serialization coding and labeling equipment

In the pharmaceutical industry, product serialization is the cornerstone of all…

Capsule checkweigher

Capsule checkweigher

The production of pharmaceutical capsules requires that individual doses are checked for accuracy. In a p…

High capacity capsule filler

High capacity capsule filler

In the highest volume pharmaceutical production environments, capsule filling needs to be extrem…

Scale up capsule filler

Scale up capsule filler

For higher production volumes of pharmaceutical capsules, speed, accuracy and reliability of productio…

Entry level capsule filler

Entry level capsule filler

For the production of pharmaceutical doses in capsule form complete accuracy of fill is paramount.…

Industrial capsule checkweigher

Industrial capsule checkweigher

Pharmaceutical manufacturing demands the highest quality standards and completely consistent …

Automatic laboratory capsule filler

Automatic laboratory capsule filler

Innovators in the highly regulated and highly dynamic pharmaceutical market place need e…

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Automatic capsule filler

Automatic capsule filler

Capsule filling should be a worry-step in pharmaceutical and nutraceutical manufacturing.  The right …

High-yield capsule filler

High-yield capsule filler

Pharmaceutical manufacturers require maximum yield from their encapsulation process for efficient p…

Easy to validate capsule filler

Easy to validate capsule filler

Staying competitive in today's highly dynamic and highly regulated pharmaceutical production …

Checkweigher for capsules

Checkweigher for capsules

The new interactive indicator unit allows for even easier use. High-rigidity weighcells have been p…

Checkweigher

Checkweigher

A check weigher that is equipped with high speed/high accuracy force balance load cell. It meets stringent accurac…

High-sensitivity metal detection system

High-sensitivity metal detection system

Highly efficient metal detector with enhanced quality control and reporting capabili…

R&D electronic counter for capsules and tablets

R&D electronic counter for capsules and tablets

This machine has been designed to offer an ever-precise and reliable count …

R&D hard gelatin capsule sealing machine

R&D hard gelatin capsule sealing machine

When encapsulating products at temperatures up to + 80°C, these tend to solidify at…

R&D capsule orientater

R&D capsule orientater

A semi-automatic orienter for capsules with an output speed up to 6000 capsules.

R&D semi-automatic capsule filler

R&D semi-automatic capsule filler

Semi-automatic filling machine suitable to open, fill and close empty hard gelatin capsule…

R&D automatic capsule filler

R&D automatic capsule filler

Automatic capsule filling machine for powders, pellets, tablets, mini-tablets, capsule in capsul…

Pharmaceutical granulator

Pharmaceutical granulator

Pharmaceutical granulators are often used with active substance mixtures to be processed into granu…

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HPMC manufacturing equipment must operate at higher temperatures


HPMC is one of many types of pharmaceutical capsules. As a result, it will require slightly different production processing. HPMC capsules is produced using a dipping-pin method, similar to the technique used to produce gelatin capsules. But the Hypromellose solution needs to be kept at higher temperatures (around 70°C), and shells take longer to form on the manufacturing pins.


Moreover, the structure of HPMC capsules is significantly more fragile than that of gelatin. Processing with drying and filling equipment must therefore operate at a gentler pace.


Hygroscopic materials are compatible HPMC capsule ingredients

One limitation of traditional animal-based gelatin is that absorbent and adsorbent materials gradually weaken the shell walls.

On the other hand, HPMC capsules offer superior stability at a broader range of heat and moisture variances. This makes them better suited for hygroscopic formulations such as zinc chloride or sodium hydroxide.

HPMC opens opportunities for the production of vegan enteric-coated tablets

The generic capsule owes its success as a pharmacological product to the efficacious delivery of drugs. HPMC capsules are not only as easy to swallow as hard-gel alternatives, but they carry an identical dissolution rate in-vivo.

In addition, the matt properties of Hypromellose make it a viable option for delayed and extended-release medical formulations. HPMC, thus, shows promise for the manufacturing of plant-based enteric-coated tablets.

Processing steps involved in hpmc-capsules making

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