Pharmaceutical granulation line

Streamline your production with an integrated system that combines mixing, granulation, and drying, delivering efficiency with minimal product loss and easy maintenance access.

Maximizes Mixing, Granulation, and Drying Efficiency

The CGS Granulation Line from DIOSNA Dierks & Söhne GmbH is engineered for pharmaceutical, food, and cosmetics industries to efficiently combine mixing, granulation, and drying processes. Geometrically optimized for seamless transition between mixer and dryer, this system minimizes product-contacting surfaces, enhancing product yield and reducing cleaning challenges. Its batch processing capability ranges from 25 to 600 kg, supported by an explosion protection feature compliant with ATEX standards, ensuring safety during solvent operations. The system’s flexibility includes integration with 21 CFR Part 11-compliant software for precise batch monitoring. Designed for ease of maintenance, the CGS Granulation Line features accessible components and supports PAT concepts to meet GAMP 5 standards.

Benefits

  • Boosts product yield with reduced product-contacting surfaces.
  • Enhances safety with integrated explosion protection compliant with ATEX standards.
  • Simplifies cleaning and inspection with fully accessible components.
  • Supports regulatory compliance with 21 CFR Part 11-compliant batch monitoring.
  • Streamlines integration into production lines with PAT-compatible design.

General


Applications
Food,Feed,Dough,Fine chemicals,Pre-dough,Cosmetics,Pharmaceutical solids
End products
Coated candy,Specialty chemicals,Pre-dough mixes,Pet food,Pastry dough,Granules,Tablets,Snack foods,Nutraceuticals,Bread dough,Animal feed pellets,Capsules,Lotions,Powdered chemicals,Creams
Steps before
Mixing,Pre-dough preparation,Kneading,Fermentation
Steps after
Drying,Quality control,Batch documentation,Cleaning and maintenance
Input ingredients
mixing ingredients,raw materials,solvent applications
Output ingredients
granulated product,pellets,batch data
Market info
Diosna is known for its expertise in manufacturing industrial dough mixing machines and systems, primarily for the bakery and food industries, showcasing a strong reputation for innovation, quality, and reliable engineered-to-order mixing solutions.

Technical Specifications


Capacity
25 to 600 kg/batch
Product Yield
Optimised due to reduced product-contacting surfaces
Explosion Protection
Integrated for solvent applications
Batch Documentation
21 CFR Part 11-compliant software
Automation
Controlled via two operator terminals
Safety Compliance
ATEX and common standards
Standards Compliance
GAMP 5
PAT Concepts
Integration feasible

Operating Characteristics


Batch vs. continuous operation
Batch
Automation level
PLC
Cleaning method
Freely accessible components
Integration of PAT concepts
Feasible
Explosion decoupling
Not necessary
Accessibility
Optimal via operating platform
Safety
ATEX explosion protection integrated

Material Compatibility


Cleanability
Effortless access for cleaning
Corrosive resistance (e.g. acids)
Explosion protection for solvent applications

Physical Characteristics


Compact footprint
Yes,space-saving design
Equipment capacity
25 to 600 kg batch size
Discharge method
Optimized transfer with reduced residues
Control panel type
Two operator terminals
Operating platform
Yes,for easy component access

Custom Options


Control panel type
21 CFR Part 11-compliant software
Integration possibilities
PAT concepts,GAMP 5 standards
Batch size customization
25 to 600 kg
Explosion protection
ATEX standards
Accessibility features
Operating platform,freely accessible components
Explosion decoupling
Not necessary
Record and documentation
21 CFR Part 11-compliant software
Safety standards
ATEX,GAMP 5
System footprint
Compact