Pilot High shear granulator for wet granulation
Achieve consistent particle sizing and superior homogeneity in your powder formulations with this versatile system, perfect for optimizing your pilot-scale wet granulation and mixing processes.
Granulates and Mixes Powder into Dense Granules
The GMXB-Pilot GRANUMEIST® from Freund is a high shear wet granulation mixer designed for precise and efficient processing in the pharmaceutical, nutraceutical, and fine chemical industries. This equipment stands out due to its bottom-drive design, which facilitates easy cleaning, faster processing times, and enhanced safety. Featuring interchangeable bowls (10L, 25L, 65L) and user-defined mixer and chopper blade speeds, it supports both aqueous and solvent processes. Its integrated peristaltic pump and optional vacuum drying make it suitable for flexible batch operations. Containment is enhanced with the optional Smart-Safe™ system, while a color touchscreen offers validatable and automated process control, aligning with 21 CFR Part 11 compliance. Engineered for scalability and equipped with proportional mixer blade tip speeds, the GMXB-Pilot accommodates diverse granulation needs, from granulated vitamins to fine chemical powders. Additionally, its quick changeover design and options for jacketed and vacuum drying bowls streamline maintenance and operational efficiency.
Benefits
- Increases operational efficiency with quick changeover design and no tools required.
- Enhances product quality through precise control of mixing and granulation processes.
- Reduces maintenance time and effort with easy-to-clean bottom-drive system.
- Offers scalability across production scales with interchangeable bowl sizes and adjusted mixer speeds.
- Ensures regulatory compliance with validatable process control supporting 21 CFR Part 11 requirements.
- Applications
- Vitamins,Supplements,Fine chemicals,Nutraceuticals,Coating materials,Pharmaceutical powders,Pharmaceuticals
- End products
- Fine chemical granules,Protein powders,Coated nutraceuticals,Tablets,Granulated vitamins,Herbal supplements,Powdered dietary supplements,Coated particle drugs,Effervescent tablets,Capsules
- Steps before
- Purification,Drying,Emulsification,Grinding
- Steps after
- Vacuum Drying,Tablet Coating,Packing,Coating,Tablet Pressing
- Input ingredients
- powders,wet granulation ingredients,aqueous solutions,solvent mixtures
- Output ingredients
- medium to high density granules
- Market info
- Freund is known for its expertise in granulation and coating technology, supplying high-quality industrial equipment for pharmaceutical, chemical, and food industries. Renowned for innovation and reliability, Freund consistently delivers engineered-to-order solutions tailored to client needs.
- Bowl Capacity
- 10L,25L,65L
- Working Capacity
- 3.0 - 7.0 L,7.5 - 17.5 L,19.5 - 45.5 L
- Automation
- Automatic (Recipe Driven) and Manual Modes
- Mixer Speed
- 75-485 RPM,50-360 RPM,40-260 RPM
- Cooling option
- Jacketed Bowl for Product Temperature Control (Optional)
- Drying integration
- Vacuum Drying for One-Pot Processing (Optional)
- Data Collection
- USB Data Collection Port
- Control System
- Color Touchscreen Control System
- Scalability
- Engineered Scalability with Proportional Mixer Blade Tip-Speeds
- Containment
- Smart-Safe™ Containment Optional
- Control System Compliance
- 21 CFR Part 11 Data,Recipe Handling System
- Working mechanism
- Bottom Drive High Shear Wet Granulation
- Integrated steps
- Mixing and granulation
- CIP/SIP
- Easy cleaning and maintenance
- Batch vs. continuous operation
- Batch
- Changeover time
- Quick Changeover - No Tools Required
- Control system
- Color Touchscreen Control System
- Scalability
- Engineered Scalability
- Automation level
- Automatic and Manual Modes
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- ISO Certification
- ISO 9001
- 21 CFR Part 11
- Data,Recipe Handling System
- Bowl Capacity
- 10L / 25L / 65L
- Working Capacity
- 3.0 - 7.0L / 7.5 - 17.5L / 19.5 - 45.5L
- Footprint
- Compact
- Interchangeable Product Bowls
- Yes
- Bottom Drive Design
- Yes
- Quick Changeover Design
- No Tools Required
- Jacketed Bowl
- Optional
- Vacuum Drying
- Optional
- Smart-Safe™ Containment
- Optional
- Control Panel Type
- Color Touchscreen
- Control Panel Type
- Color Touchscreen Control System
- Integration Possibilities
- USB Data Collection Port
- Automation Control
- Automatic (Recipe Driven) and Manual Modes
- Process Control
- Validatable Process Control
- Blade Speed Settings
- User Defined Settings For Mixer and Chopper Blade Speeds
- Product Temperature Control
- Jacketed Bowl (Optional)
- Vacuum Drying
- Optional for One-Pot Processing
- Safety Features
- Smart-Safe™ Containment Optional
- Scalability
- Engineered Scalability
- Control System Compliance
- 21 CFR Part 11 Data,Recipe Handling System