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The fizz of effervescent tablets is commonly associated with a vitamin C boost. But the soluble pill is an excellent drug delivery method for pediatric and geriatric patients. Sometimes referred to as carbon tablets, manufacturing effervescent tablets binds biocarbonate and citric acid that produce the smooth hiss as they dissolve in liquid.

What effervescent tablets equipment do you need?

Granulation line for pharmaceutical solid dosage forms

Granulation is a common technique in production of pharmaceutical ...

Industrial scale tablet coater

During the coating process, tablets pass many stages that can make them wet and sticky or cra...

Fluid bed dryer for pharmaceutical solid dosage form

Fluid bed drying is a pharmaceutical process carried out to reduce t...

Industrial high shear mixer granulator for drug formation

It is rather difficult to successfully produce a pharmaceutica...

Tablet coater for laboratory scale

Tablet coating can be applied for adding colours or glosses, or based around sugar in or...

High Speed Double-Sided Tablet Press

To achieve as much as double the output of single-sided tablet press, the upper and lo...

High Speed Tablet Press

High speed pharmaceutical tablet presses convert powder to tablets. The operations should be quick an...

High-speed strip packaging machine

Pack your solid pharmaceutical products in four-side sealed foil packs at very high spee...

Automatic filling line for solid doses

For medium-scale production of solid doses such as tablets, capsules, and softgels t...

Benchtop tablet press

For lab work or small-scale production, a purpose-designed tablet press that meets your exact requireme...

Feeder with flexible wall hopper

The varying properties of dry powder products mean that specialized feeders are required fo...

Small feeder with flexible wall hopper

In many laboratory applications and production processes, smaller quantities of powd...

Conical mill for drug formulation

The efficient size reduction of granular powders is a key step in many pharmaceutical pro...

Automatic tablet coater for lab scale

The ability to coat tablets in an even and controlled way is an important stage in th...

Tablet auto coater for lab scale

Many pharmaceutical doses in tablet form require a coating before they are ready for use. T...

Single and double layer tablet press

High performance tablet presses that are capable of producing both single and double-l...

Granulation line of mixer and fluid bed dryer

A complete granulation line allows for the mixing and granulation of pharmac...

Microencapsulation system for your drug delivery system

Whether you want to improve the stability of nutrients, protect a...

Single layer tablet press

High performance tablet presses for the modern production environment need to be fast, accurate an...

Rotary tablet press

For pharmaceutical tablet producers looking to reduce waste, costs and  increase production volume, a hig...

Fluid bed dryer for production scale

Fluidized bed drying (FBD) is a common process in the pharmaceutical industry for dryi...

Fluid bed dryer for lab scale

Fluidised bed drying (FBD) is a common process in the pharmaceutical industry for drying compo...

Fluid bed dryer and mixer for lab scale

Designed for pharmaceutical R&D, a lab-scale fluid bed dryer and mixer/granulat...

High-shear mixer

For the efficient mixing of larger batches of pharmaceutical compounds and high-shear mixer provides the opti...

Entry-level high-shear mixer for drug formulation

For pilot and lab-scale pharmaceutical formulations, a high-shear granu...

Premium vacuum conveyor

When you have a need to tailor make your conveyor and still have the high requirement on hygiene, e.g...

Sorption dehumidifier with air-chilled condenser

It is not always possible to duct out the wet air from a dehumidifier ser...

Small portable dehumidifier

Water damaged areas require dehumidification to limit the damage and prepare the area for restor...

Sorption dehumidifier for large temperature differences

Small, humid areas can be difficult to dehumidify in humid ambien...

Sorption dehumidifier for deep drying

Humid ambient conditions such as those in tropical climates make dehumidification mor...

Dehumidifier for difficult wet airflows

Sealed rooms can be challenging to dehumidify with ordinary dehumidifiers. The wet ...

Sorption dehumidifier for overpressured rooms

Small humid spaces, used for processing or storage, often need a simple dehu...

Heat recycling sorption dehumidifier

Facilities that handle large amounts of water can become very humid. High humidity may...

Industrial desiccant dehumidifier

Dehumidification of medium sized manufacturing and processing facilities can be a dauntin...

Large scale desiccant dehumidifier

Moisture sensitive processing and storage facilities need low humidity environments to s...

Customizable dehumidifier

Dehumidification needs can vary significantly from one project to another. Dehumidifiers with a fi...

Economic dispersing machine for emulsions and suspensions

For products of medium viscosity and relatively consistent par...

Ultra-fine dispersing machine for emulsions and suspensions

Producing the finest micro-emulsions and suspensions require...

High-speed blister machine

If you are looking for a compact machine that produces blisters with an output of up to 700 blist...

Horizontal intermittent motion cartoner

User-friendly cartooning solution with an intermittent motion for a wide range of p...

Horizontal continuous motion cartoner

An automatic cartoning machine designed for both high-speed operations and medium pac...

Pick and place transfer for strips into cartoner

Transfer your strip packs products directly to the cartoner.

Versatile strip packaging machine

Pack diverse products such as diagnostics, pharmaceutical liquids or flat, stable product...

Strip packaging machine for effervescent tablets

Pack your effervescent tablets with extreme precision and care at a speed...

Entry-level blister machine

A start-up solution for contract packing and generics manufacturing with an easy-to-get upgrade ...

Compact blister machine

A compact blister machine ideal for packing tablets, capsules, ampoules and syringes and other applic...

Case packer for cartons and bundles

Pack cartons and bundles into RSC (Regular Slotted Case) cases and perform functions li...

Stretch bander

A compact wrapping machine to seal your boxes with a max speed of 50 packs per minute.

Vertical cartoner

A cartoning solution that can be operated in either continuous or intermittent mode depending on the carton...

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Tell us about your production challenge

When selecting production equipment for a production plant, it is important to talk to someone with experience in your field. Our industry experts have experience with various industrial applications. We’d love to help you!
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Manufacturing effervescent tablets with a mix of lubricants reduces scumming

Water-soluble lubricants such as sodium benzoate have an added benefit in acting as glidants when manufacturing effervescent tablets. The anti-adherent properties of the organic salt add plasticity to the final product.

However, the inclusion of other lubricants like magnesium stearate and polyethylene glycol in negligible amounts reduces scumming in the final solution.

Limit humidity to 1.0% weight during wet granulation

Moisture levels are restrained to between 18°C and 23°C, with 10% relative humidity during the manufacturing process.

This presents an added challenge when wet granulation is performed. During this stage, water is kept to a maximum of 1.0% weight by weight of the mixture. Granules are then immediately conveyed to an oven dryer.

Apply drying agents in tube packaging

Avoid polymer blister materials or tubes for packaging that let in moisture and air. The compaction of effervescent tablets traps air bubbles. But if the tablets are exposed to water or oxygen, these will trigger the effervescent reaction ahead of use.

Blister packaging and aluminum foil protect the tablets from the surrounding environment following manufacturing. In the case of tubes, drying agents or silica gel prevents the penetration of humidity and air.

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