Bench-top mixer and spheronizer for formulation development

Accelerate R&D success by seamlessly integrating mixing, extrusion, and spheronization processes in a single bench-top unit, providing unparalleled control and data-driven insights for precise formulation development.

Mixes, Extrudes, and Spheronizes Formulation Batches

The Multi Lab Scientific (MLS) from Caleva Process Solutions is a versatile bench-top mixer, extruder, and spheronizer designed for small batch formulation development in pharmaceutical and biotech research. This equipment integrates digital controls for automated data capture and recipe management, ensuring consistent and repeatable results. It operates with a compact footprint, making it ideal for laboratory environments focused on precision and efficiency. The MLS supports applications like the production of controlled-release tablets, effervescent tablets, and microencapsulated fish oil, facilitating processes such as mixing, extrusion, and spheronization. It offers a processing capacity for small batches starting from 15 grams, tailored for research and development teams aiming to optimize formulation parameters. The equipment’s tool-less technology simplifies operation and maintenance, while its compliance with GLP standards ensures data integrity and enhances research accuracy.

Benefits

  • Enhances formulation accuracy and consistency with automated data capture and recipe management.
  • Saves time and reduces errors by eliminating the need for handwritten experiment notes.
  • Ensures precise scale-up with reliable repeatability across multiple iterations.
  • Protects operator safety with a high-integrity, hinged safety guard.
  • Simplifies maintenance and operation with tool-less attachment technology.

General


Applications
Supplements,Nutraceuticals,Pellets,Extrusion,Formulation development,Spheronization,Beads,Tablet formulation,Pharmaceuticals
End products
Microencapsulated fish oil,Gummy vitamins,Sustained-release granules,Active ingredient beads,Probiotic capsules,Herbal extract pellets,Enteric-coated tablets,Nutritional supplement capsules,Effervescent tablets,Controlled-release tablets
Steps before
Wet Mass Granulation,Formulation Preparation
Steps after
Drying,Coating,Tablet Pressing,Analysis
Input ingredients
wet mass granulation,pharmaceutical formulation ingredients
Output ingredients
pellets,beads,extrudates,spheronized products
Market info
Caleva Process Solutions is known for manufacturing and supplying specialized equipment for pellet and extrudate production in the pharmaceutical, nutraceutical, chemical, and food industries, emphasizing innovative process solutions and customer-focused engineering.

Technical Specifications


Touchscreen Display
7”
User Interface
Intuitive
Recipe Management
Automatic
Data Capture
Automated
Batch Size
From 15 g
Power Supply
230v 50/60Hz or 110v 50/60Hz
Software Version
MLS1.01
Ambient Temperature Measurement
Yes
Process Temperature Measurement
Yes
Motor Load Reporting
Motor load % reporting
RPM Speed Reporting
Yes

Operating Characteristics


Automation level
Automatic
Batch vs. continuous operation
Batch
CIP/SIP
Manual cleaning
Cleaning method
Tool-less quick release
Recipe management
Digital recipe management
Data capture
Automatic
Safety features
Hinged safety guard with quick release

Material Compatibility


Density/particle size
0.5–2.5 g/cm³ / 50–1000 µm

Product type Characteristics


Formulation development
Wet Mass Granulation
Repeatability
High
Industries
Pharmaceutical,Research

Physical Characteristics


Machine footprint
Compact bench-top design
Control panel type
7” touchscreen display
Batch size
From 15 g
Discharge method
n/a
Safety features
Hinged safety guard with high-integrity safety device
Tool attachment
Tool-less,quick attach/remove

Custom Options


Control panel type
7” touchscreen display with user interface
Integration possibilities
USB microscope imaging,automated data capture
Recipe management
Digital,programmable via touchscreen or wireless keyboard
Safety features
Hinged safety guard with high-integrity device
Automation level
Manual / Automatic control
Batch size flexibility
From 15 g (bowl and formulation dependent)