Media and buffer preparation solution for bioprocessing
In biotechnological and biopharmaceutical production, the precise preparation of media and buffer solutions is critical. This process, occurring both upstream and downstream, demands sterile and dust-free environments to ensure reproducibility and success.
Sterile transfer and dust-free powder addition
The media and buffer preparation solution from Bioengineering addresses the demanding requirements of high-precision bioprocessing environments. The system features sterilizable stainless-steel vessels ranging from 30 to 20,000 liters in capacity, and autoclavable stainless-steel containers from 10 to 50 liters, as well as glass bottles with capacities from 0.5 to 10 liters. Powder is introduced into the vessels using dust-free systems such as the Cup-Hermann powder transfer system, drum-lift systems, or vacuum-feed systems, thereby ensuring a clean transfer. Dissolution of the powder is achieved through suitable stirrers or circulation pumps, ensuring thorough yet gentle mixing. Further, the system supports flexible transfer methods from on/off pumps to fully-automated metering systems operated by pressure. This fully integrated solution offers level control, weight control, pH control, sterilization, and comprehensive documentation, supporting seamless integration into the clean-in-place (CIP) systems. Bioengineering’s solution ensures the precise and sterile preparation and transfer of media and buffers, supporting optimal performance in cell culture and microbial fermentation processes.
Benefits
- Sterilizable and autoclavable vessels for safe preparation
- Dust-free powder transfer systems prevent contamination
- Versatile capacity options to match specific process requirements
- Thorough yet gentle dissolution with appropriate stirrers or pumps
- Full integration with CIP systems for enhanced cleanliness