High shear wet granulation line

Achieve consistent and uniform granules with energy-efficient wet granulation designed to optimize mixing and drying, simplifying your formulation process and enhancing end-product quality.

Homogenizes and Granulates Powders Efficiently

The GMX GRANUMEIST® from Freund is a high shear wet granulator and mixer designed for pharmaceutical, nutraceutical, and fine chemical applications. It features a top-drive system, simplifying cleaning and maintenance while enhancing user safety. This equipment excels in creating consistent granule density and homogeneity for products like effervescent tablets, protein powders, and APIs. With bowl capacities ranging from 150L to 1200L, it supports batch operations and integrates easily into existing production lines with user-defined mixer and chopper speeds. The system offers optional vacuum drying for one-pot processing and an EcoClean™ technology for efficient cleaning. Compatible with cGMP standards, it promotes secure operations with a Smart-Safe™ containment option and features a color touch screen for process control, supported by multiple end-point detection parameters.

Benefits

  • Enhances production efficiency by achieving consistent granule density and homogeneity.
  • Reduces cleaning time and maintenance efforts with a top-drive design and removable components.
  • Increases processing flexibility with user-defined mixer and chopper speeds.
  • Complies with cGMP standards, ensuring safe and secure pharmaceutical manufacturing.
  • Supports diverse product processing, including powders, granules, and liquids, for versatile applications.

General


Applications
Vitamins,Supplements,Fine chemicals,Pharmaceutical tablets,Nutraceuticals,Pharmaceutical powder,Biopharmaceuticals
End products
Dietary supplement granules,Multivitamin tablets,Active pharmaceutical ingredients (apis),Vitamin c tablets,Chewable vitamins,Probiotic capsules,Protein supplement powders,Enzyme supplements,Effervescent tablets,Omega-3 capsules
Steps before
Mixing,Powder Blending
Steps after
Drying,Tablet Coating,Roller Compaction,Tableting
Input ingredients
powders,aqueous solutions,solvents
Output ingredients
medium density granules,high density granules,wet granules
Market info
Freund is known for its expertise in granulation and coating technology, supplying high-quality industrial equipment for pharmaceutical, chemical, and food industries. Renowned for innovation and reliability, Freund consistently delivers engineered-to-order solutions tailored to client needs.

Technical Specifications


Capacity
50–800 L
Batch vs. continuous
Batch
Mixer Power
User-Defined
Granulation Time
Multiple End-Point Detection
Automation
Automatic (Recipe Driven) and Manual Mode
Data Collection
USB Data Collection Port
Processing Type
Aqueous and Solvent Processing
Temperature Control
Optional Jacketed Bowl for Product Temperature Control
Cleaning Method
Single Point Connection For Cleaning Solutions
Control System
Color Touch Screen Control System
Containment
Smart-Safe™ Containment Optional
Control System
COMPUTMAutomated Control System
Compliance
21 CFR Part 11 Data,Recipe Handling System

Operating Characteristics


Working Mechanism
High Shear Wet Granulation
Integrated Steps
One-Pot Processing
Batch vs. Continuous Operation
Batch
CIP/SIP
CIP Integrated
Automation Level
Automatic and Manual Modes
Cleaning Method
CIP / Removable Bowl and Mixing Blade
Processing Flexibility
Aqueous and Solvent Processing
User-Defined Mixer and Chopper Speeds
Available
Drying Integration
Optional Vacuum Drying

Material Compatibility


Abrasion resistance
Yes
Cleanability
Easy cleaning with removable parts
Corrosive resistance (e.g. acids)
Optional jacketed bowl for corrosion resistance
Density/particle size
0.5–2.5 g/cm³ / 50–1000 µm

Product type Characteristics


Integrated processing
Vacuum drying (optional)

Physical Characteristics


Machine Footprint
Reduced processing area required
Bowls Available
Removable bowl,additional bowl for quick process changeover (optional)
Mixing Blade
Removable with fixed bowl lid
Top Drive Design
Allows for easy cleaning and maintenance
Vertical Shaft Chopper
For improved granulation
Bowl Capacity
150L to 1200L
Working Capacity
50L to 800L

Custom Options


Control panel type
Color Touch Screen Control System
Integration possibilities
21 CFR Part 11 Data,Recipe Handling System
Installation
Optional Stand-Alone Installation Available
Processing Flexibility
User-Defined Mixer and Chopper Speeds
Containment Technology
Smart-Safe™ Containment Optional
Cleaning Technology
EcoClean™ Technology
Process Control
Automated (Recipe Driven) and Manual Mode
Additional Features
Removable Bowl and Mixing Blade with Fixed Bowl Lid
Additional Options
Optional Vacuum Drying for One-Pot Processing
Product Temperature Control
Optional Jacketed Bowl
System Connection
Single Point Connection For Cleaning Solutions
End-Point Detection
Multiple Parameters