Tell us about your production challenge

Vitamin C is an essential nutrient, but the human species lost the ability to produce it biologically during the course of evolution. Instead, we source the substance either from whole foods or vitamin C manufacturing. The chemical characteristics of the natural nutrient and processed compound are the same, but supplements offer higher concentrations, especially to persons with nutrient deficiencies.

What vitamin c equipment do you need?

Granulation line for pharmaceutical solid dosage forms

Granulation is a common technique in production of pharmaceutical ...

Industrial scale tablet coater

During the coating process, tablets pass many stages that can make them wet and sticky or cra...

Tablet coater for laboratory scale

Tablet coating can be applied for adding colours or glosses, or based around sugar in or...

Tablet counting machine

Production of pharmaceutical solid dosage forms usually require complete accuracy, flexibility, and c...

Hygienic floor scale

The food and pharmaceutical industries require maintaining high levels of sanitations as well as logisti...

Hygienic floor scale with lifting device

The food and pharmaceutical industries require maintaining high levels of sanitati...

Hygienic mobile scale

Having a reliable and accurate weighing and measuring solution is absolutely essential, especially in t...

Gravimetric powder microdosing 2 - 100 g

Powders and granules are commonly dosed for the manufacturing of pharmaceuticals, ...

Metal detector for tablets and capsules

Identification of metallic contaminants is a vital part of pharmaceutical quality c...

Dust-tight metal detector for tablets

For FDA-compliant production of tablets, the elimination of airborne dust containing ...

Wash-in-Place metal detector for tablets

Where hygiene and decontamination are vital, traditional pharmaceutical metal dete...

R&D V-type powder blender

Many pharmaceutical processes rely on the complete blending and homogenizing of different powd...

Benchtop tablet press

For lab work or small-scale production, a purpose-designed tablet press that meets your exact requireme...

Automatic laboratory capsule filler

Innovators in the highly regulated and highly dynamic pharmaceutical market place need ...

Automatic capsule filler

Capsule filling should be a worry-step in pharmaceutical and nutraceutical manufacturing.  The right...

Economic tablet press

Successful pharmaceutical manufacturers know that high quality, reliable equipment is essential in orde...

Single rotary tablet press

Creating batches of consistent high quality pharmaceutical grade tablets from your powdered ingre...

Checkweigher for sachets and sticks

The checkweighers for multiple lanes have a 1.5 times faster response speed and 2 times...

Automatic tablet coater for lab scale

The ability to coat tablets in an even and controlled way is an important stage in th...

Lab scale single layer tablet press

Automated pressing of tablets saves time and improves quality. In R&D or laboratory...

Single layer tablet press

High performance tablet presses for the modern production environment need to be fast, accurate an...

Stickpack Machine

If you are looking to pack your product into stick packs from 17 x 40 mm to 100 x 200 mm in size, you may b...

Waste minimization weight sorter for tablets & capsules

For medium scale production, you can improve line efficiency and ...

Premium vacuum conveyor

When you have a need to tailor make your conveyor and still have the high requirement on hygiene, e.g...

Horizontal pharmaceutical scraper centrifuge

For slurries difficult to discharge, a scraper can improve process reliabilit...

Isolator centrifuge

For transfering highly active pharmaceutical ingredients (HAPI) without contamination from the isolator c...

Mobile pilot plant centrifuge

The system is perfectly suited for pilot plants as well as small-quantity productions in the f...

Vertical top discharge centrifuge

Discharge solids vertically upward through manual action, optionally using a filter bag o...

Vertical peeler centrifuge

A vertical peeler centrifuge is used to separate solids, usually to separate fine particles from ...

Vertical scraper centrifuges

Vertical Bottom discharge Centrifuges work discontinuously, discharging the solids to the botto...

Pusher centrifuge

Pusher centrifuges are continuously operating filter centrifuges and can have several basket stages dependi...

Pelleting press with overhead drive

Production of certain pelletized products requires working with output products of a pa...

Show more equipment
Contact us

Tell us about your production challenge

When selecting production equipment for a production plant, it is important to talk to someone with experience in your field. Our industry experts have experience with various industrial applications. We’d love to help you!
Contact us

Sorbitol fermentation achieves nature-identical synthesis of vitamin C

Vegetables and fruits such as kale and lemon are rich sources of vitamin C. But the natural compound is susceptible to light and oxygen, which could dent the extraction yield of processing. Instead, industrial production often relies on crops like corn and wheat for vitamin C manufacturing.

Sorbitol derived from the feedstock undergoes a double cycle of fermentation and filter pressing to synthesize ascorbic acid. The two-step fermentation process recovers around 60% of the product with 95% purity.

Chemically modified disintegrants break up the binders faster

The bioavailability of synthetic vitamin C is identical to that in food-derived vitamins. But the efficacy of supplements also depends on other ingredients besides ascorbic acid.

Disintegrating agents such as cellulose gum or starch facilitate absorption by the body after the dosage is ingested. Meanwhile, advances in this department are developing superdisintegrants that counter the strength of binders to speed up the release of the vitamins.

Add the right lubricants to address sticking issues during production

The flowability of the raw materials presents a significant challenge to vitamin C manufacturing. Apart from risks of caking, lack of flow can result in surface imperfections in the final capsule or tablet. Additives like magnesium stearate or stearic acid act as lubricants to decrease friction between the tablet and the forming die.

Silicon dioxide or other flow agents prevent the formation of lumps as the granules travel along the production line.

Label the packaging quantities in terms of the daily vitamin requirement

As a producer, you must always declare the nutrient reference values (NRV) of vitamin C supplements. International labeling guidelines stipulate that these values should be expressed in metric units or as a percentage of the recommended daily allowance (RDA).

In 2019, the Food and Agriculture Organization set the RDA of vitamin C for adults at 60 milligrams. However, national authorities may establish different quantities. Authorities in the US and EU recommend a daily intake of 80 milligrams for adult females and 90 milligrams for adult males.

Let's talk about your project!

Try us and get in touch. Send us a message and we will try to reply within 24 hours or give us a call at +31 10 206 8000
Contact us
All your data is kept confidential