Spherical vacuum dryer for Apis and fine chemicals

Achieve precise moisture control and efficient drying for APIs and fine chemicals with our versatile spherical vacuum dryer, engineered for optimized batch processes and seamless integration into your production line.

Dries, Mixes, and Discharges Powder Formulations

The MAVASPHERE® from GMM Pfaudler is a spherical vacuum dryer designed for pharmaceutical and fine chemical manufacturing, ensuring exceptional drying performance and efficient operations. It features an eccentrically mounted agitator that provides uniform mixing and drying, with minimal product hold-up for easy cleaning and validation. Suitable for Active Pharmaceutical Ingredients (APIs) and chemicals such as paracetamol and aspirin, it operates with various filling capacities and a good turndown ratio.

This multi-purpose dryer integrates seamlessly into your production line with temperature-controlled automation units and vacuum systems for solvent recovery. Made from Stainless Steel, Hastelloy, and special alloys, it offers superior corrosion resistance, meeting cGMP and FDA guidelines. The optional dry9000® shaft sealing system and chopper for effective lump breaking enhance its versatility. A compact design reduces the footprint, and its CIP system supports contamination-free cleaning, minimizing downtime and ensuring compliance with industry standards.

Benefits

  • Enhances product quality with uniform drying and mixing capabilities.
  • Reduces cleaning time through minimal product hold-up and CIP system.
  • Increases operational efficiency by recovering solvents during the drying process.
  • Durable in harsh chemical environments with corrosion-resistant material options.
  • Complies with cGMP and FDA standards, ensuring regulatory adherence.

General


Applications
Chemicals,Active pharmaceutical ingredients,Fine chemicals,Powder formulations,Pharmaceuticals
End products
Paracetamol,Aspirin,Vitamin c,Caffeine,Benzoic acid,Penicillin,Ibuprofen,Erythromycin,Calcium carbonate powder,Citric acid
Steps before
Filtration,Solvent Recovery,Membrane Separation
Steps after
Packaging,Sterilization
Input ingredients
Active Pharmaceutical Ingredients (API's),Fine Chemicals
Output ingredients
Dried Active Pharmaceutical Ingredients,Dried Fine Chemicals,Lump-free products
Market info
GMM Pfaudler is known for manufacturing glass-lined equipment, reactors, and engineered-to-order (ETO) solutions for the chemical, pharmaceutical, and allied industries, recognized for their innovation, quality, and global presence.

Technical Specifications


Compliance
cGMP,FDA
Filling Capacities
Wide range
Turndown Ratio
Good
Discharge Method
Spherical disc valve
Clearance
Minimal between vessel wall and agitator
Construction Materials
Stainless Steel,Hastelloy,Special Alloys
Shaft Sealing System
Interseal Dry9000®,Gas lubricated double mechanical seal
Agitator Type
Hollow heated,rotating 3-blade
Automation Systems
Temperature control units,Vacuum and solvent recovery units,Powder handling / Pack-off systems
Accessories
Lump Breaker,Dust Filter,Sampling System

Operating Characteristics


Working Mechanism
Vacuum drying
Integrated Steps
Drying and mixing
Mixing Method
Agitator with minimal clearance
Batch Operation
Batch process
Cleaning Method
Easy cleaning and validation
Discharge Method
Bottom discharge with spherical disc valve
Automation Level
Available with automation systems
Energy Efficiency
Compact system with lower footprint

Material Compatibility


Corrosive resistance
Stainless Steel,Hastelloy,Special Alloys
Cleanability
Minimal product hold-up

Physical Characteristics


Compact footprint
Lower footprint
Discharge method
Spherical disc valve at lowest point
Machine shape
Spherical
Agitator type
Eccentrically top mounted with heated,rotating 3-blade
Material of construction
Stainless Steel,Hastelloy,Special Alloys

Custom Options


Shaft Sealing Design
Interseal Dry9000® shaft sealing system
Agitator
Hollow heated,rotating 3-blade
Gas Lubricated Double Mechanical Seal
Installed outside of the product zone
Bottom Discharge
Spherical disc valve for quick opening
Standard Accessories
Lump Breaker,Dust Filter,Sampling System
Optional Accessories
Vessel flange with bayonet type,quick-closing design
Automation Systems
Temperature control units,Vacuum and solvent recovery units,Powder handling / Pack-off systems