Dissolution testing system with Hplc analysis
Streamline your dissolution testing with integrated HPLC analysis, offering precise, semi-automated procedures for reliable, contamination-free drug dissolution results.

Performs HPLC-Integrated Dissolution Testing
The ERWEKA Dissolution HPLC On-/Offline System is a semi-automatic solution designed to enhance pharmaceutical testing precision. By integrating the DT 950 dissolution tester with HPLC online analysis, it automates up to five of eight dissolution steps, ensuring USP/EP/JP compliance. It tackles common contamination issues utilizing double filtration with the maintenance-free PVP 820 pump and AFC 825 filter changer, capable of filtrations up to 0.22 µm. Disso.NET software orchestrates the entire process, offering extensive data management and method development tools. Ideally used for testing pharmaceutical tablets and powders, this system supports seamless sample collection and analysis, significantly improving accuracy and throughput in R&D and quality control operations. Customizable with optional spectrophotometers and compatible with major HPLC brands, it facilitates night-time operation without manual intervention, addressing the need for high-efficiency dissolution testing.
Benefits
- Enhances analytical precision by automating up to five dissolution steps, reducing human error.
- Minimizes contamination risk with double filtration, protecting HPLC columns and ensuring data accuracy.
- Reduces operational costs with a maintenance-free PVP pump and automated filter changer.
- Facilitates seamless integration with existing systems, supporting major HPLC brands for flexibility.
- Enables nighttime, unsupervised operations, optimizing laboratory productivity and resource allocation.
- Applications
- Supplements,Pharmaceutical tablets,Nutraceuticals,Pharmaceutical powder,Biopharmaceuticals
- End products
- Dietary fiber supplements,Sustained-release tablets,Turmeric capsules,Immediate-release tablets,Vitamin c tablets,Fish oil capsules,Powdered antibiotics,Protein supplements,Effervescent tablets,Powdered probiotics
- Steps before
- Media Preparation,Dissolution Testing
- Steps after
- HPLC Analysis,Data Evaluation,Report Generation
- Input ingredients
- dissolution test samples,test medium,samples in transfer block,diluted samples,samples stored against UV radiation
- Output ingredients
- dissolution test results,filtered samples,HPLC analysis results,comprehensive reports,exported test data
- Market info
- ERWEKA is renowned for manufacturing high-quality pharmaceutical testing equipment, including dissolution testers, tablet hardness testers, and other analytical instruments, known for their precision and reliability in laboratory testing environments.
- Compliance
- 100% USP/EP/JP compliant
- Filtration precision
- Up to 0.22 µm
- Automation level
- Semi-automatic
- Sampling capacity
- Up to 5 of 8 steps automated
- Medium compatibility
- 8 channels high pressure
- Software control
- Controlled by Disso.NET
- Documentation
- Audit trail enabled
- Filter changer
- Automatic,AFC 825
- Temperature monitoring
- Real-time
- Rotation speed recording
- Real-time
- Pump type
- Maintenance-free PVP pump
- Sampler control
- Automatically controlled
- Filtration method
- Double filtration
- HPLC Analysis
- Automated
- Software compatibility
- LIMS connection
- Automation level
- Semi-automatic
- Batch vs. continuous operation
- Batch
- Cleaning method
- Automatic Filter Change
- Integrated steps
- Sampling,Filtration,HPLC Analysis
- Working mechanism
- Dissolution Testing with HPLC Integration
- Energy efficiency
- Maintenance-free PVP Pump
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- GMP Compliance
- Yes
- USP Compliance
- USP 1,2,5,6
- EP Compliance
- Yes
- JP Compliance
- Yes
- FDA Compliance
- Yes
- Compact footprint
- Yes
- Discharge method
- Automatic / Manual
- Control panel type
- Touchscreen / Button Interface
- Machine material
- Stainless Steel
- Filtration system type
- Double Filtration
- Filter size compatibility
- 0.22 μm membrane
- Sample handling
- Automatic / Manual
- Integration possibilities
- Disso.NET software,HPLC system integration
- Control Panel Type
- Disso.NET software control
- Filtration Options
- Double filtration with AFC 825
- Sample Collection Method
- HPLC sampler with cooling and UV protection
- Bypass System
- AFC 825 integrated bypass for media replacement
- Pump Type
- PVP 820 high-precision,maintenance-free
- Software Features
- Method editor,audit trail,data export
- Sampler Detection
- Automatic injection syringe position detection
- Filter Changer Configuration
- AFC 825 with 12 or 16 valves
- Filter Types
- Acrodisc™ PSF,glass fiber syringe filters