Intermediate bulk container (ibc) blending for pharmaceutical manufacturing
Streamline your pharmaceutical blending process with robust IBC technology, ensuring uniform powder mixing and enhanced process control while maintaining product integrity and reducing contamination risks.
Blends and Homogenizes Pharmaceutical Powders and Granules
GEA’s IBC Blenders offer robust solutions for pharmaceutical powder processing, featuring designs like the Pedestal Blender and SP30 Laboratory Blender. These units ensure homogeneous blending using GEA’s unique Prism technology, optimizing batch quality and efficiency. Suitable for producing paracetamol tablets, vitamin supplements, and biopharmaceutical products, they serve both production and R&D facilities. The Pedestal Blenders handle volumes up to 3000 L, using air-driven screw jacks for secure, continuous operation without utility interruptions. They incorporate comprehensive control systems, such as Siemens S7 PLCs, ensuring precision and reduced downtime. The equipment is designed for GMP compliance, with options for stainless steel construction to support cleanroom environments. For process analytics, PAT technologies, including NIR systems, enhance real-time process monitoring and control. Integrating seamlessly into existing production lines, these blenders support both pilot and full-scale manufacturing processes, providing energy-efficient, low-maintenance solutions customizable to specific production needs.
Benefits
- Enhances product consistency and quality with precise, homogeneous blending.
- Minimizes contamination risks through secure, fail-safe clamping and isolation design.
- Reduces operational costs with energy-efficient motor control and minimal maintenance requirements.
- Facilitates scale-up from lab to full production with adaptable volume capacities.
- Ensures regulatory compliance with GMP and FDA standards.
- Applications
- Supplements,Fine chemicals,Pharmaceutical tablets,Nutraceuticals,Pharmaceutical powder,Biopharmaceuticals
- End products
- Fish oil supplements,Vitamin c tablets,Antioxidant supplements,Ibuprofen powder,Api (active pharmaceutical ingredient) granules,Protein supplements,Biopharmaceutical monoclonal antibodies,Omega-3 capsules,Paracetamol tablets,Ascorbic acid powder
- Steps before
- Product Handling,Granulation,Pre-Blending
- Steps after
- Discharge,Milling,Roller Compaction,Packaging
- Input ingredients
- granules,powders,dry powders,granular material,pharmaceutical materials
- Output ingredients
- homogenous product blend,blended granules,blended powders,dry blend,direct compression formulations
- Market info
- GEA is known for its expertise in engineering innovative and sustainable equipment and solutions, focusing on sectors such as food, beverages, pharmaceuticals, and energy, with a reputation for quality, efficiency, and advanced technological applications in industrial processing.
- Automation
- PLC-controlled,21 CFR Part 11-compliant
- IBC Volume
- Up to 3000 L
- Max. Working Load
- 900kg-2500kg depending on model
- Drive Motor Power
- 4.0 kW - 15 kW
- Clamping System
- Pneumatically operated screw jacks
- Control Systems
- Siemens S7 Series PLC,Allen Bradley FlexLogix PLC
- Airtight Wall Plate
- Supplied
- Blending Prism Technology
- Low shear mixing
- Swinging Arms Feature
- Enables range of IBC volumes
- Process Analytical Technology
- Light Induced Florescence (LIF) or Near-Infrared (NIR)
- Pedestal Design
- Single and Double Pedestal
- Working Mechanism
- Rotating IBC with blending Prism
- Automation Level
- User-friendly PLC-controlled system
- Batch vs. Continuous Operation
- Batch
- CIP/SIP
- Cleaning in Place,GEA Wash Station
- Blending Speed Control
- Variable Speed Drive
- Integrated Steps
- Blending,PAT analysis
- Safety Features
- Air-driven screw jacks,positive IBC detection
- Energy Efficiency
- 0.5-2 kWh/kg of process
- Changeover Time
- Efficient due to fast loading/unloading
- Product Containment
- Improved containment and batch integrity
- Blending Method
- Homogenous blending with Prism
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Machine Footprint
- Varies depending on model (e.g.,SP1000,DP3000)
- IBC Size
- 700L to 3000L
- IBC Footprint
- 1125mm x 1325mm to 1350mm x 1590mm
- Control Panel Type
- Siemens or Allen Bradley
- Container Type
- IBC
- Drive Motor
- 4.0 Kw to 15 Kw
- Discharge Method
- IBC-to-IBC,Gravity Discharge
- Compact Footprint
- Through-the-Wall Design
- Pedestal Type
- Single or Double Pedestal
- Max Working Load
- 900kg to 2500kg
- Control panel type
- Siemens S7 Series PLC,Allen Bradley FlexLogix PLC
- Variable speed drive
- Danfoss VLT Series
- Process Analytical Technologies
- Light Induced Fluorescence (LIF),Near-Infrared (NIR) systems
- Blending Prism
- Low shear mixing for homogenous blending
- Swinging Arms
- Handles various IBC volumes