Fluid-bed granulator for top-spray applications
In pharmaceutical manufacturing, ensuring uniform particle size in granulation can be challenging when working with batch processes. Processing efficiency and operational safety are often major concerns, requiring reliable technology to optimize granulation and drying.
Granulate and dry batches up to 125 liters
The FBE 125 X•ONE from ACG World is an advanced fluid-bed system designed for top-spray granulation and drying. Developed at the company’s Design Centre in Mülheim, Germany, it offers superior performance and operational safety. With a working volume range from 33 to 168 liters, it is suitable for handling batches up to 125 liters. The system includes a 12-bar pressure-shock-resistant design featuring the MOST™ concept, approved by FSA from Germany and compliant with ATEX (Directive 2014/34/EU). The unique C-flanges prevent explosion pressure transfer beyond the unit, and the X•ONE inflatable seals ensure safety at pressures as low as 4.5 bar. The integrated QASV (Quick Action Stop Valves) contain explosions within 20 milliseconds. Additionally, the X•ONE command process control system provides secure and intuitive monitoring, compliant with GAMP 5 and 21 CFR Part 11 standards. The unit comes with customized charging, discharging, and WIP (wash-in-place) systems for efficient processing and reduced changeover times.
Benefits
- Ensures safety with 12-bar pressure shock resistance
- Customizable solutions for efficient granule processing
- Minimal mechanical deformation and downtime
- Secure and intuitive process control
- Reduces explosion risk with Quick Action Stop Valves