Let's make microtablets
Microtablets range between 1 and 4 millimeters, making the dosage form an excellent delivery system in polypharmacy. The size of the products makes them easier pills to swallow, but microtablets production brings a unique set of complexities.
What microtablets equipment do you need?
Granulation line for pharmaceutical solid dosage forms
Granulation is a common technique in production of pharmaceutical ...
Industrial scale tablet coater
During the coating process, tablets pass many stages that can make them wet and sticky or cra...
Fluid bed dryer for pharmaceutical solid dosage form
Fluid bed drying is a pharmaceutical process carried out to reduce t...
Industrial high shear mixer granulator for drug formation
It is rather difficult to successfully produce a pharmaceutica...
Tablet coater for laboratory scale
Tablet coating can be applied for adding colours or glosses, or based around sugar in or...
High-speed strip packaging machine
Pack your solid pharmaceutical products in four-side sealed foil packs at very high spee...
Automatic filling line for solid doses
For medium-scale production of solid doses such as tablets, capsules, and softgels t...
Benchtop tablet press
For lab work or small-scale production, a purpose-designed tablet press that meets your exact requireme...
Automatic capsule filler
Capsule filling should be a worry-step in pharmaceutical and nutraceutical manufacturing. The right...
Contained capsule filler
For pharmaceutical formulations that are highly active specialized capsule filling equipment is ofte...
High-yield capsule filler
Pharmaceutical manufacturers require maximum yield from their encapsulation process for efficient ...
Feeder with flexible wall hopper
The varying properties of dry powder products mean that specialized feeders are required fo...
Small feeder with flexible wall hopper
In many laboratory applications and production processes, smaller quantities of powd...
Conical mill for drug formulation
The efficient size reduction of granular powders is a key step in many pharmaceutical pro...
Single and double layer tablet press
High performance tablet presses that are capable of producing both single and double-l...
Granulation line of mixer and fluid bed dryer
A complete granulation line allows for the mixing and granulation of pharmac...
Microencapsulation system for your drug delivery system
Whether you want to improve the stability of nutrients, protect a...
Single layer tablet press
High performance tablet presses for the modern production environment need to be fast, accurate an...
Rotary tablet press
For pharmaceutical tablet producers looking to reduce waste, costs and increase production volume, a hig...
Fluid bed dryer for production scale
Fluidized bed drying (FBD) is a common process in the pharmaceutical industry for dryi...
Fluid bed dryer for lab scale
Fluidised bed drying (FBD) is a common process in the pharmaceutical industry for drying compo...
Fluid bed dryer and mixer for lab scale
Designed for pharmaceutical R&D, a lab-scale fluid bed dryer and mixer/granulat...
High-shear mixer
For the efficient mixing of larger batches of pharmaceutical compounds and high-shear mixer provides the opti...
Entry-level high-shear mixer for drug formulation
For pilot and lab-scale pharmaceutical formulations, a high-shear granu...
R&D automatic capsule filler
Automatic capsule filling machine for powders, pellets, tablets, mini-tablets, capsule in c...
Premium vacuum conveyor
When you have a need to tailor make your conveyor and still have the high requirement on hygiene, e.g...
Sorption dehumidifier with air-chilled condenser
It is not always possible to duct out the wet air from a dehumidifier ser...
Small portable dehumidifier
Water damaged areas require dehumidification to limit the damage and prepare the area for restor...
Sorption dehumidifier for large temperature differences
Small, humid areas can be difficult to dehumidify in humid ambien...
Sorption dehumidifier for deep drying
Humid ambient conditions such as those in tropical climates make dehumidification mor...
Dehumidifier for difficult wet airflows
Sealed rooms can be challenging to dehumidify with ordinary dehumidifiers. The wet ...
Sorption dehumidifier for overpressured rooms
Small humid spaces, used for processing or storage, often need a simple dehu...
Heat recycling sorption dehumidifier
Facilities that handle large amounts of water can become very humid. High humidity may...
Industrial desiccant dehumidifier
Dehumidification of medium sized manufacturing and processing facilities can be a dauntin...
Large scale desiccant dehumidifier
Moisture sensitive processing and storage facilities need low humidity environments to s...
Customizable dehumidifier
Dehumidification needs can vary significantly from one project to another. Dehumidifiers with a fi...
Economic dispersing machine for emulsions and suspensions
For products of medium viscosity and relatively consistent par...
Ultra-fine dispersing machine for emulsions and suspensions
Producing the finest micro-emulsions and suspensions require...
Laboratory dispersing machine for low-viscous masses
Laboratory mixers have not always been easy to work with. Getting a...
High-speed blister machine
If you are looking for a compact machine that produces blisters with an output of up to 700 blist...
Horizontal intermittent motion cartoner
User-friendly cartooning solution with an intermittent motion for a wide range of p...
Horizontal continuous motion cartoner
An automatic cartoning machine designed for both high-speed operations and medium pac...
Pick and place transfer for strips into cartoner
Transfer your strip packs products directly to the cartoner.
Versatile strip packaging machine
Pack diverse products such as diagnostics, pharmaceutical liquids or flat, stable product...
Entry-level blister machine
A start-up solution for contract packing and generics manufacturing with an easy-to-get upgrade ...
Compact blister machine
A compact blister machine ideal for packing tablets, capsules, ampoules and syringes and other applic...
Case packer for cartons and bundles
Pack cartons and bundles into RSC (Regular Slotted Case) cases and perform functions li...
Stretch bander
A compact wrapping machine to seal your boxes with a max speed of 50 packs per minute.
Vertical cartoner
A cartoning solution that can be operated in either continuous or intermittent mode depending on the carton...
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Tell us about your production challenge
Align the punches in multi-tip tooling technology with precision
The millimetric dimensions of microtablets make compression force harder to control than for larger-sized tablets.
Adopting multi-tip tooling in your microtablets production process multiplies overall compression power by the number of tips in the equipment. While this technique distributes the weight in microtablets more evenly, misalignment between the upper and lower punch results in faulty compression.
Extend the coating process in microtablets production
The reduced diameter of microtablets gives them a larger surface area relative to regular-sized tablets. This physical property increases the speed of drug release once ingested and decreases the diffusion rate of the active pharmaceutical ingredients.
Microtablets designed for delayed release require an extended coating process. Spray coating using a fluidized bed system achieves uniform coats, but a high spray rate can develop cracks down the line if temperatures are too low for adherence.
Set your friability limit to 1% of body weight in minitablet production
The friability threshold of microtablets must not exceed a reduction of 1% in the total weight of the tablets.
Select a dusted sample with a total body weight of 6.5 g a place it into a rotating drum. After the rotating cycle is completed, dust the microtablets again and measure the weight. Check the products for chips or cracks.
Processing steps involved in microtablets making
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