Isolator high containment for granule production
Ensure high-purity production in pharmaceuticals with controlled granulation processes, all within a contained environment eliminating the need for a clean room setup.
Controls Containment and Processes Powders in Isolated Environment
The Isolator High Containment System from Three-Tec offers a complete solution for pharmaceutical and fine chemical processes requiring stringent containment. Designed to integrate a feeder, extruder, conveyor belt with cooling, and granulator, this system ensures transformation from powder mixing to finished granules within a sealed environment, eliminating the need for a full clean room. Notably, it supports applications including the production of tablets, capsules, and APIs, with end-products extending to protein and herbal powders.
Its continuous operation is controlled centrally, enhancing efficiency and allowing manual intervention for tasks such as disassembly and cleaning of systems, which are made from stainless steel 1.4404 (316 L) with a surface finish of Ra ≤ 0.8 µm for optimal corrosion resistance. Ensuring compliance with ISO 14644-7 and OEB 4 / OEB 5 standards, the isolator creates a safe environment for operators while maintaining high production integrity. This system is highly suitable for pharmaceutical manufacturers and research laboratories seeking flexibility and precision in high containment processes.
Benefits
- Ensures operator safety and product integrity with OEB 4 / OEB 5 compliant containment.
- Reduces setup costs by eliminating the need for a full clean room.
- Simplifies cleaning and maintenance with easily disassembled stainless steel components.
- Facilitates versatile applications, from pharmaceuticals to fine chemicals.
- Enhances process control through centralized operation management.
- Applications
- Supplements,Fine chemicals,Nutraceuticals,Pharmaceutical powders,Pharmaceuticals
- End products
- Herbal extract powders,Powder supplements,Active pharmaceutical ingredients (apis),Granules,Fine chemical intermediates,Protein powders,Tablets,Vitamin c powder,Capsules
- Steps before
- Powder Mixing
- Steps after
- Sterilization,Packing
- Input ingredients
- powder,raw materials
- Output ingredients
- finished granules
- Market info
- Three-Tec is known for its expertise in manufacturing precision dosing and feeding systems for industrial applications, with a strong reputation for customizable engineered-to-order equipment and innovative solutions tailored to specific customer needs.
- Compliance
- ISO 14644-7
- Containment Level
- OEB 4 / OEB 5
- Material
- Stainless steel 1.4404 (316 L)
- Surface Finish
- Ra ≤ 0.8 µm
- Feeder Model
- ZD 5-12 mm FB
- Extruder Model
- ZE 5-18 mm
- Control System
- Central
- Conveyor Belt
- With Cooling
- Pelletizer
- Standard
- Working Mechanism
- Feeder,Extruder,Conveyor Belt,Granulator
- Integrated Steps
- Powder Mixing to Granulation
- Batch vs. Continuous Operation
- Batch
- Cleaning Method
- Manual with Glove Handling
- Environment Control
- High Containment OEB 4 / OEB 5
- Automation Level
- Central Control System
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Machine footprint
- Compact
- Material
- Stainless Steel 1.4404 (316 L)
- Surface finish
- Ra ≤ 0.8 µm
- Feed/Discharge Method
- Integrated conveyor belt with cooling
- Working chamber design
- Designed for handling with gloves
- Control system
- Central
- Equipment placement flexibility
- High Containment OEB 4 / OEB 5
- Handling method
- Glove handling
- Material construction
- Stainless steel 1.4404 (316 L)
- Cleaning method
- Easy disassembly and cleaning