Closed loop granulator for pharmaceutical production
Streamline your production with a fully automated closed-loop system, ensuring efficient mixing, granulation, and drying processes while minimizing contamination risks and maximizing yield rates.

Granulates, Mixes, Dries, and Transfers Powders
The Closed Loop Granulator by Fabtech is an engineered solution tailored for pharmaceutical and biotech manufacturers, designed to streamline the complex granulation workflow. This system integrates Rapid Mixer Granulator, Fluid Bed Equipment, Vacuum Transfer System, Co mill, and Blender into one cohesive unit, ensuring efficient, contamination-free processing of powders and granules.
The granulator operates in a fully automated, closed-loop sequence, which minimizes human intervention and enhances operator safety by utilizing SS 316 L pipelines for enclosed product transfer. Specifically developed for applications in pharmaceuticals, biotech products, and nutraceuticals, it is ideal for producing pharmaceutical capsules, enzyme powders, and herbal supplements. This system supports batch sizes of up to 300 kg and is cGMP and 21 CFR Part 11 compliant, ensuring alignment with industry standards.
Fabtech’s granulator reduces operational space requirements and offers significant productivity gains via rapid product transfers. Energy efficiency and process safety are prioritized with an integrated Active-Passive-Valve system for contained loading and unloading. Available in stainless steel 316 or 316L to counteract corrosion, the system offers mirror-finished contact parts for easy maintenance, supported by its dust-free and CIP-enabled design. Customization options and engineering support are available to tailor the granulator to your specific production needs.
Benefits
- Enhances productivity with fast and efficient product transfer, minimizing downtime.
- Ensures high product quality and safety with enclosed, dust-free operations.
- Lowers operational costs by reducing human intervention through full automation.
- Supports industry compliance with cGMP and 21 CFR Part 11 certifications.
- Offers flexible production capabilities with batch sizes up to 300 kg.
- Applications
- Supplements,Pharmaceutical tablets,Nutraceuticals,Biotech products,Powder formulations,Pharmaceuticals
- End products
- Pharmaceutical capsules,Antipyretic tablets,Herbal supplements,Nutraceutical protein powder,Biotech enzyme powders,Vitamin c powder
- Steps before
- Mixing,Rapid Mixing,Granulation
- Steps after
- Drying,Co Milling,Blending,Packing
- Input ingredients
- raw materials,granules,powder
- Output ingredients
- granulated product,finished product,high yield output
- Market info
- Automation
- Fully automated
- Batch size
- Up to 300 kgs
- Material
- SS 316/SS316L
- Pipeline material
- SS 316 L breaded flexible pipelines
- Contact parts finish
- Mirror-finished
- Non-contact parts finish
- Matt-finished
- Compliance
- cGMP and 21 CFR Part 11 compliant
- Automation Level
- Fully Automated
- Cleaning Method
- Closed Loop CIP
- Batch vs. Continuous Operation
- Batch
- Process Safety
- Enhanced Operator and Environment Safety
- Dust-free Operation
- Yes
- Integrated Steps
- Rapid Mixer Granulator,Fluid Bed Equipment,Vacuum Transfer System,Dry Co mill,Blender
- Material Transfer
- Contained Product Transfer
- Changeover Time
- Fast Product Transfer
- Abrasion resistance
- Yes
- Biological compatibility
- Pharmaceutical grade
- Cleanability
- cGMP compliant
- Corrosive resistance (e.g. acids)
- SS 316/SS316L
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Machine footprint
- Compact
- Low space occupation
- Construction Material
- SS 316L
- Pipeline material
- SS 316L breaded flexible pipelines
- Contact Surface Finish
- Mirror-finished
- Non-Contact Surface Finish
- Matt-finished
- Batch size
- Up to 300 kg
- Models available
- Lab,pilot,commercial production
- Control panel type
- PLC / SCADA
- Integration Possibilities
- Lab,Pilot,and Commercial Models
- Pipeline Materials
- SS 316 L
- Equipment Connection
- Flexible Breaded Pipelines
- Cleaning Assurance
- High Assurance of Cleaning