Closed loop granulator for pharmaceutical production

Streamline your production with a fully automated closed-loop system, ensuring efficient mixing, granulation, and drying processes while minimizing contamination risks and maximizing yield rates.

Granulates, Mixes, Dries, and Transfers Powders

The Closed Loop Granulator by Fabtech is an engineered solution tailored for pharmaceutical and biotech manufacturers, designed to streamline the complex granulation workflow. This system integrates Rapid Mixer Granulator, Fluid Bed Equipment, Vacuum Transfer System, Co mill, and Blender into one cohesive unit, ensuring efficient, contamination-free processing of powders and granules.

The granulator operates in a fully automated, closed-loop sequence, which minimizes human intervention and enhances operator safety by utilizing SS 316 L pipelines for enclosed product transfer. Specifically developed for applications in pharmaceuticals, biotech products, and nutraceuticals, it is ideal for producing pharmaceutical capsules, enzyme powders, and herbal supplements. This system supports batch sizes of up to 300 kg and is cGMP and 21 CFR Part 11 compliant, ensuring alignment with industry standards.

Fabtech’s granulator reduces operational space requirements and offers significant productivity gains via rapid product transfers. Energy efficiency and process safety are prioritized with an integrated Active-Passive-Valve system for contained loading and unloading. Available in stainless steel 316 or 316L to counteract corrosion, the system offers mirror-finished contact parts for easy maintenance, supported by its dust-free and CIP-enabled design. Customization options and engineering support are available to tailor the granulator to your specific production needs.

Benefits

  • Enhances productivity with fast and efficient product transfer, minimizing downtime.
  • Ensures high product quality and safety with enclosed, dust-free operations.
  • Lowers operational costs by reducing human intervention through full automation.
  • Supports industry compliance with cGMP and 21 CFR Part 11 certifications.
  • Offers flexible production capabilities with batch sizes up to 300 kg.

General


Applications
Supplements,Pharmaceutical tablets,Nutraceuticals,Biotech products,Powder formulations,Pharmaceuticals
End products
Pharmaceutical capsules,Antipyretic tablets,Herbal supplements,Nutraceutical protein powder,Biotech enzyme powders,Vitamin c powder
Steps before
Mixing,Rapid Mixing,Granulation
Steps after
Drying,Co Milling,Blending,Packing
Input ingredients
raw materials,granules,powder
Output ingredients
granulated product,finished product,high yield output
Market info

Technical Specifications


Automation
Fully automated
Batch size
Up to 300 kgs
Material
SS 316/SS316L
Pipeline material
SS 316 L breaded flexible pipelines
Contact parts finish
Mirror-finished
Non-contact parts finish
Matt-finished
Compliance
cGMP and 21 CFR Part 11 compliant

Operating Characteristics


Automation Level
Fully Automated
Cleaning Method
Closed Loop CIP
Batch vs. Continuous Operation
Batch
Process Safety
Enhanced Operator and Environment Safety
Dust-free Operation
Yes
Integrated Steps
Rapid Mixer Granulator,Fluid Bed Equipment,Vacuum Transfer System,Dry Co mill,Blender
Material Transfer
Contained Product Transfer
Changeover Time
Fast Product Transfer

Material Compatibility


Abrasion resistance
Yes
Biological compatibility
Pharmaceutical grade
Cleanability
cGMP compliant
Corrosive resistance (e.g. acids)
SS 316/SS316L
Density/particle size
0.5–2.5 g/cm³ / 50–1000 µm

Physical Characteristics


Machine footprint
Compact
Low space occupation
Construction Material
SS 316L
Pipeline material
SS 316L breaded flexible pipelines
Contact Surface Finish
Mirror-finished
Non-Contact Surface Finish
Matt-finished
Batch size
Up to 300 kg
Models available
Lab,pilot,commercial production

Custom Options


Control panel type
PLC / SCADA
Integration Possibilities
Lab,Pilot,and Commercial Models
Pipeline Materials
SS 316 L
Equipment Connection
Flexible Breaded Pipelines
Cleaning Assurance
High Assurance of Cleaning