High shear granulation mixing system
Optimize your powder granulation process with a system designed for precise control over granule density and homogeneity, ensuring efficient batch production while maintaining rigorous safety and cleanliness standards.
Processes and Mixes Powders into Granules
The GMXB GRANUMEIST® from Freund is a high shear wet granulation mixer designed to transform powders into uniform, medium to high-density granules for pharmaceutical, nutraceutical, and chemical industries. Its bottom-drive design ensures efficient mixing, supported by GMP-compliant, 316 stainless steel construction that facilitates easy cleaning and inspection. With variable mixer and chopper blade speeds, it adapts to aqueous and solvent-based processes, while optional vacuum drying ensures one-pot processing. Configurable models accommodate capacities from 30 to 1,800 liters, with EcoClean™ technology ensuring efficient cleaning through single-point connections, and the Smart-Safe™ containment option addressing safety and containment needs. This solution offers precision via VFD-controlled blade speeds and automated recipe-driven control systems, ensuring compliance with FDA 21 CFR Part 11 for secure data management.
Benefits
- Enhances product uniformity and quality with precise granule density control.
- Simplifies cleaning and reduces contamination risk with GMP-compliant design.
- Optimizes processing efficiency with user-defined settings and automated control.
- Increases operational flexibility with compatibility for both aqueous and solvent processes.
- Ensures regulatory compliance and secure data handling with 21 CFR Part 11 support.
- Applications
- Vitamins,Supplements,Fine chemicals,Nutraceuticals,Enzymes,Coating materials,Pharmaceuticals
- End products
- Dietary supplement granules,Coated fine chemical powders,Effervescent vitamin tablets,Controlled-release medication granules,Nutraceutical tablets,Tablet granules,Enzyme granules,Vitamin capsules
- Steps before
- Mixing,Weighing,Sieving,Pre-mixing
- Steps after
- Drying,Compression,Coating,Packing
- Input ingredients
- powders
- Output ingredients
- medium density granule,high density granule
- Market info
- Freund is known for its expertise in granulation and coating technology, supplying high-quality industrial equipment for pharmaceutical, chemical, and food industries. Renowned for innovation and reliability, Freund consistently delivers engineered-to-order solutions tailored to client needs.
- Material
- 316 Stainless Steel
- Capacity
- 30 - 1800 Liters
- Automation
- Automatic (Recipe Driven) and Manual Modes
- Granulation Method
- Wet Granulation
- Temperature Control
- Jacketed Bowl for Product Temperature Control (Optional)
- Pressure Capability
- Optional 12-Bar Pressure Rated Construction
- Drying Option
- Vacuum Drying for One-Pot Processing (Optional)
- Blade Speed
- User-Defined Settings for Mixer and Chopper Blade Speeds
- Control System
- Color Touch Screen Control System
- Data Collection Port
- USB Data Collection Port
- End-Point Detection Parameters
- Mixer Power,Granulation Time
- Compliance
- GMP-Compliant Design
- Scalability
- Engineered Scalability with User-Defined Blade Tip-Speeds via VFD
- Working mechanism
- High Shear Wet Granulation
- Integrated steps
- Wet Granulation and Mixing
- CIP/SIP
- Easy cleaning with GMP compliance
- Batch vs. continuous operation
- Batch Operation
- Automation level
- Manual / Automatic (Recipe Driven)
- Cleaning method
- EcoClean™ Technology
- Processing flexibility
- Aqueous and Solvent Processing
- Temperature control
- Jacketed Bowl (Optional)
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Stainless Steel Construction
- 316 Stainless Steel
- Machine size
- Varies by model
- Product Charge System
- Full Range
- Product Discharge System
- Full Range
- Enclosure
- Floor to Bowl Level
- Optional Pressure Rating
- 12-Bar
- Jacketed Bowl
- Optional
- Vacuum Drying Feature
- Optional
- Control panel type
- Color Touch Screen
- Integration possibilities
- 21 CFR Part 11 Data,Recipe Handling System
- User-Defined Settings
- Mixer and Chopper Blade Speeds
- Customization of Blade Tip-Speeds
- User-Defined via VFD
- Temperature Control Option
- Jacketed Bowl (Optional)
- Vacuum Drying Integration
- One-Pot Processing (Optional)