Single-use batch chromatography systems for biopharmaceuticals
In biopharmaceutical manufacturing, the purification of biological products such as monoclonal antibodies (mAbs) often presents challenges such as inefficient resin usage and extensive downtime for column packing and cleaning. These issues can significantly delay production timelines and increase costs.

Optimize purification processes with multi-column efficiency
The Resolute® BioSMB from Sartorius AG is designed to revolutionize biopharmaceutical purification through its advanced multi-column chromatography system. This system optimizes resin utilization by employing a continuous multi-column setup, greatly minimizing resin volume requirements by up to 80%. It also boosts productivity by as much as 5 times compared to traditional single-column setups. The system’s design allows for reduced buffer consumption, further cutting down on operational costs. With automated switching between columns, the need for extensive manual intervention is removed, streamlining the entire process. The Resolute® BioSMB is a suitable choice for the biopharmaceutical industry, particularly in processes requiring high efficiency and reduced cycle times.
Benefits
- Significant resin volume reduction, saving up to 80%
- Increased productivity, boosting output by up to 5 times
- Lower buffer consumption, reducing operational costs
- Automated column switching, minimizing manual intervention
- Streamlined process, suitable for high-efficiency purification in biopharmaceuticals