Single-use batch chromatography systems for biopharmaceuticals

Streamline your purification process with high productivity and reduced resin costs, enabling efficient downstream operations for complex biomolecules.

Purifies Biomolecules and Accelerates Chromatography Processes

Sartorius’ Sartobind® Rapid A, part of its esteemed chromatography portfolio, is specialized for swift and efficient biomolecule purification. This membrane system excel in high-throughput applications, leveraging rapid cycling to achieve up to 14x productivity increase during capture stages, beneficial for monoclonal antibodies and vaccine manufacturing. It eliminates the need for column packing, reducing operational time and freeing up your resources. Designed for column-free operation, it requires no additional setup, ensuring immediate deployment within your production line. Capable of integrating with existing systems, it supports batch and continuous operations, ideal for pharmaceutical and biotechnology environments. The Sartobind® Rapid A offers substantial cost savings by minimizing resin volumes used, contributing to reduced operational costs and increased process efficiency. Every unit is constructed to uphold compliance with GMP standards, facilitating seamless production while ensuring safety and reliability. With membrane chromatography’s inherent energy efficiency, anticipate a reduction in energy consumption throughout your bioprocessing activities.

Benefits

  • Increases productivity by up to 14x with rapid cycling, enhancing process efficiency.
  • Eliminates column packing, saving time and operational resources.
  • Reduces resin volume costs by up to 80%, offering significant operational savings.
  • Complies with GMP standards, ensuring safety and regulatory adherence.
  • Lowers energy consumption, contributing to sustainable bioprocessing.

General


Applications
Supplements,Vitamins,Vaccines,Fine chemicals,Medical devices,Nutraceuticals,Cell therapy,Monoclonal antibodies,Mrna production,Biosimilars,Plasma,Bioconjugation,Biopharmaceuticals,Gene therapy,Regenerative medicine,Enzymes,Pharmaceutical powders,Essential oils
End products
Car-t cell therapies,Flavor enhancers,Pharmaceutical-grade lactose,Insulin pens,Fish oil supplements,Vitamin c tablets,Gene-editing therapies,Antioxidant supplements,Biosimilar infliximab,Antibody-drug conjugates,Monoclonal antibody therapeutics,Protease enzymes,Stem cell therapies,Mrna vaccines,Gamma globulin,Viral vector vaccines
Steps before
Upstream Processing,Bioreactor Operation,Cell Culture,Fermentation,Media Preparation
Steps after
Downstream Processing,Purification,Buffer Exchange,Sterile Filtration,Viral Clearance
Input ingredients
nucleic acids,viral particles,exosomes,cell culture media,buffers,biomolecules,plasmids,monoclonal antibodies,growth factors,cytokines
Output ingredients
purified nucleic acids,purified viral particles,purified exosomes,biopharmaceuticals,purified monoclonal antibodies,purified biomolecules,polished therapeutic proteins
Market info
Sartorius AG is renowned for manufacturing high-precision laboratory and bioprocess equipment. They specialize in filtration, fermentation, and cell cultivation systems, known for their innovation and reliability in the pharmaceutical and biotech industries.

Technical Specifications


Automation
PLC-controlled
Batch vs. continuous
Batch or inline
Capacity
50–2000 kg/h
Filling speed
10k–150k/hr
Filling volume
1 ml – 5 L
Filtration type
Depth / membrane / crossflow
Feed rate
50–1000 kg/h
Aeration rate
0.5–2 vvm
Cooling temperature
4–15°C
Cycle temperature
121–135°C

Operating Characteristics


Working mechanism
Chromatography systems
Integrated steps
Multi-step chromatography
CIP/SIP
Aseptic conditions and cleaning
Batch vs. continuous operation
Batch and continuous systems
Automation level
PLC / SCADA systems
Energy efficiency
Low consumption systems

Material Compatibility


Density/Particle Size
0.5–2.5 g/cm³ / 50–1000 µm

Product type Characteristics


Viscosity
Low,Medium,High
Heat Sensitivity
Yes/No

Custom Options


Control panel type
PLC / HMI
Integration possibilities
Modular integration / Automation compatibility
Column configuration
Multi-column / Single-column
Process scalability
Batch / Continuous operation
System configurability
Customizable workflows / Tailored solutions
Membrane type
Monolithic / Sartobind® Membrane
Software integrations
SCADA / Automation systems support