Integrated granulation train for pharmaceutical processes
In pharmaceutical manufacturing, achieving efficient and dust-free granulation processes is essential for producing high-quality products. Traditional approaches often fall short in terms of efficiency, safety, and space utilization, posing significant challenges for manufacturers.
Combines high-shear mixing and fluid-bed systems
The GT series from ACG World is an integrated granulation system designed to optimize manufacturing efficiency while ensuring safe, single-handed operation. The system combines an advanced high-shear mixer (HSM) and fluid-bed (FBE/FBC) system, which are designed in Germany. It achieves a highly efficient, dust-free wet granulation process within a cost-effective, closed-loop design. The contained product handling is supported by a vacuum charging system that ensures closed-loop transfer for smooth material flow and minimum product leftover. The compact design reduces floorspace requirements by around 50%, and the through-the-wall construction allows clear separation between processing and technical areas, ensuring easier maintenance, cleaning, operation, and GMP compliance. Additionally, multiple systems for charging, discharging, and WIP (wash-in-place) minimize dust generation and product exposure, making GMP compliance easier. The equipment can be customized to a wide range of product and process requirements.
Benefits
- Closed-loop product transfer ensures safety and smooth material flow.
- Reduces floorspace requirements by approximately 50%.
- Through-the-wall construction aids in maintenance and GMP compliance.
- Minimizes dust generation and manual intervention.
- Customizable to specific product and process needs.