Integrated granulation train for pharmaceutical processes

Achieve precise granulation, uniform mixing, and efficient drying with an integrated solution, ensuring seamless operations and maintaining product integrity throughout the pharmaceutical production line.

Processes and Mixes Powders into Granules

The GT Series from ACG is an integrated granulation train combining high-shear mixing and fluid bed technology, engineered specifically for the pharmaceutical and nutraceutical industries. This system excels in processing pharmaceutical powders into granules and is capable of handling a variety of end-products, including effervescent tablets and multivitamin capsules. Utilizing a closed-loop system, it ensures precise granulation, drying, and material transfer, significantly reducing dust and product loss. With a compact footprint and through-the-wall construction, the GT Series facilitates easy maintenance and clean operations in compliance with GMP standards. The equipment supports both batch and continuous operations, offering flexible configurations to match diverse formulation needs. Enhanced by energy-efficient components, the GT Series not only minimizes operational costs but also complies with rigorous pharmaceutical and nutraceutical production protocols.

Benefits

  • Enhances production efficiency with its seamless integration of granulation and drying processes.
  • Minimizes product waste through its closed-loop system, ensuring optimal material usage.
  • Reduces facility footprint by 50% with its compact and efficient design.
  • Facilitates easy maintenance and cleaning, ensuring continuous GMP compliance.
  • Customizable setup allows adaptation to a wide range of product and process requirements.

General


Applications
Vitamins,Supplements,Nutraceuticals,Pharmaceutical powder,Pharmaceuticals
End products
Calcium tablets,Omega-3 softgels,Multivitamin capsules,Vitamin c tablets,Herbal extract capsules,Probiotic supplements,Protein powder,Effervescent tablets
Steps before
Purification,Drying,Milling
Steps after
Coating,Packing,Tablet Pressing
Input ingredients
raw pharmaceutical materials,granulation formulation,powdered ingredients
Output ingredients
wet granules,finished granulation products,processed pharmaceutical materials
Market info
ACG World is known for its expertise in manufacturing pharmaceutical and nutraceutical processing and packaging machinery, offering innovative equipment solutions and maintaining a strong reputation for quality and reliability in the global market.

Technical Specifications


Automation
Single-handed operation
Capacity
Customizable with HSM and FBE/FBC options
Compact footprint
Reduces floorspace requirements by around 50%
Cleaning method
WIP (wash-in-place) system
Dust Generation
Greatly reduced
Granulation process
Dust-free wet granulation
Product transfer
Vacuum charging system
Separation Method
Through-the-wall construction
Customizability
Wide variety of combination options

Operating Characteristics


Integrated Steps
High-shear mixer and fluid-bed system
Operation Method
Single-handed operation
Automation Level
Manual / PLC / SCADA
Batch vs. Continuous Operation
Batch
Cleaning Method
Wash-in-place (WIP)
CIP/SIP
CIP 121°C / SIP 135°C
Energy Efficiency
0.5–2 kWh/kg moisture
Compact Machine Footprint
Reduces floorspace by 50%

Material Compatibility


Density/particle size
0.5–2.5 g/cm³ / 50–1000 µm

Product type Characteristics


Customization options
Easily customisable to product and process requirements

Physical Characteristics


Compact machine footprint
Reduces floorspace requirements by around 50%
Through-the-wall construction
Allows separation between processing and technical areas
Contained product-handling
Supported by a vacuum charging system
Discharge method
Closed-loop product transfer

Custom Options


Control panel type
HMI
Compact footprint
Reduces floorspace by around 50%