Sublimation front monitoring system for freeze drying
During freeze-drying processes, understanding the advancement of the sublimation front in real time is essential. This helps ensure the drying cycle’s robustness and repeatability, maintaining critical product quality attributes.
Monitor sublimation front temperature in real time
The Sublime is a Real-time Sublimation Front Advance Monitoring System developed by Telstar. It addresses the need for precise control of sublimation front temperature during the primary drying phase. This system uses single-use, wireless probes to monitor the sublimation front temperature interface, displaying data in real time. The wireless design simplifies introduction and retrieval logistics, reducing cross-contamination risks. Its five independent temperature sensors ensure accurate measurements, and it is compatible with fully automatic loading and unloading systems. The system is cGMP compliant and meets FDA 21 CFR part 11 requirements. The pre-sterilized, ready-to-use probes and centering pieces make the system highly practical for routine use in pharmaceutical and biotechnology freeze-drying applications.
Benefits
- Improved process understanding and optimization.
- Simplified logistics for probe introduction and retrieval.
- Cost-effective single-use probes.
- Reduced risk of cross-contamination.
- Real-time, accurate multipoint temperature readings.