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Monitoring Systems

Sampling is the process of aseptically drawing a sample from the process for analysis, without disturbing the bioprocess itself. The bioprocess needs to be carefully controlled by measuring important process variables and parameters. These parameters include pH, temperature, dissolved oxygen, foam/level, and agitation. The controllers use PID or auto-tuning adaptive control to measure and regulate the process parameters. The choice of a suitable controller depends on the identification of critical process variables.

Biotech sampling and control

Legal and safety provisions may require you to package your goods with a serial code detailing information related to production date, lot classification, company certification and other parameters. Serialization equipment generates the data according to the criteria in your industry and jurisdiction to ensure compliance with the prescribed standards.

Serialization equipment

Industrial Software

Tamper evident systems

monitoring-process

Monitoring-process

You can’t buy happiness, but you can buy chocolate; that’s basically the same thing. We were not surprised to discover that chocolate - to be specific, cocoa beans – was so valuable that it was used as a currency in Mayan times. When making chocolate, cocoa beans need to be dried, fermented, and roasted before using chocolate making equipment to turn them into your favorite chocolate product.

Chocolate

Bakery production includes foods usually made from flour such as bread, biscuits, and cakes. Depending on the baked good you want to make, flour can be mixed with water or other ingredients producing a paste called dough or batter. The dough is then baked in the oven using dry heat. During baking, heat is transferred from the air to the dough, first on the surface and then in the center. Moisture and liquids escape through evaporation.

Bakery

Industrially manufactured soups gained traction in the 19th century when canning was invented and they have been warming us ever since. Whether it’s a classic ready-to-eat canned soup, condensed soup or a dry soup mix, soup manufacturing equipment for mixing, cooking, boiling, or sterilizing caters to every manufacturer’s production requirements.

Soup

Sauces bring personality to a dish. From a spicy, dense Zhoug to a tangy, runny Suero, sauces add an extra dimension of flavor, texture, and mouthfeel. But developing recipes into industrial products with long shelf lives and consistent tastes is a complex process. Specialized sauce making equipment prepares and combines the ingredients into delicious, high-quality foods. The result is a sauce ready to elevate meals.

Sauce

Spreads

Parenteral preparations refer to drugs using non-oral means of administration. Injectables, such as needles and syringes, are used to deliver a drug into the systemic circulation directly in the veins, muscles, under the skin, or in the tissue.

These parenteral formulations are pharmaceutical dosage forms that have strict regulations on being sterile, pyrogen-free, and free from visible particulate matter including reconstituted sterile powders. Solutions, suspensions, emulsions, and gels with APIs intended for administration by injection are usually supplied in vials, ampoules, pre-filled syringes, or pens to facilitate ease of use.

Injectables

The topical route is a convenient route for the self-administration of drugs. But turning a pharmaceutical formulation into an easy-to-use cream involves specialized cream manufacturing equipment. Topical dosage forms are essentially an emulsion of oil and water.  But the ratios can be changed to process it into lotions, ointments, and gels.

Cream

According to a legend, Cleopatra soaked her sails in her perfume so that Mark Antony could smell her ships before they arrived. This is to say that, from soaps and shampoos to perfumes, conditioners and pomades, cosmetics have always been highly valued and used for their properties of aesthetic enhancement. Cosmetics are a broad class of topical agents applied for various purposes such as cleansing, protecting, beautifying, or otherwise altering your appearance. As a result, a wide array of processing equipment is used in the cosmetics industry.

Cosmetics

Eating is more than just nutrition, but we have found ways to increase the nourishing power of our foods. Nutraceuticals manufacturing, from vitamin C powder and probiotics to omega 3 oil, is a concentration of natural ingredients and health supplements that complement our diets. While dietary supplements are not quite haute cuisine, the process of extraction and purification is no less a blend of science and art.

Nutraceuticals

Pigments are colorants that are not soluble in the host material and scatter light and are therefore opaque. Pigments can be organic or man-made and derive from animals, plants, rocks or minerals and metal oxides, like for example titanium oxide.

Pigment

Our food chain starts in the soil, growing crops and livestock. But between the fields and the stores, there is a line of industrial food processing equipment. Processes may be as minimalistic as cleaning fruit and as complex as homogenizing milk alternatives made from pressed legumes. In each case, processing technology is an important link in the food production chain.

Food

Due to their potential hazardous nature, chemicals are classified for proper identification and safety during production. Chemical classification depends on their properties, structures and functions. In the chemical industry, you can regard them as basic chemicals such as acids, chemical products to produce plastic materials and finished chemicals for use in cosmetology. As a manufacturer or engineer, you want to know their reactivity when using chemical processing equipment.

Chemicals

Pharmaceutical developments walk side by side with health advances to provide new medicines, treatments, and therapies that have increased life quality and extended life expectancy by years. Pharmaceutical manufacturing equipment helps deliver products to a great deal of the population, but there’s a significant share that doesn’t benefit from them yet. Over 2 billion people cannot get the medicines they need, according to the United Nations Industrial Development Organization, and local production might be a way to provide for these people.

Pharmaceuticals

Biopharmaceuticals are drugs in which the active substance is manufactured or extracted from biological origin materials. They are usually produced in bioreactors by plant cells, microbial cells, yeast cultures, or mammalian cells. Also known as biomanufacturing, they are used to either treat or diagnose and prevent a patient’s medical condition or disease. Biopharmaceuticals are typically complex macromolecules administered by injection or infusions, and examples include vaccines, serums, and insulin.

Biopharmaceuticals

With the right processing machines, almonds, cashews, pine nuts, hemp, coconut, oat and soy can be processed into healthy plant-based milk. To produce it, grind the raw materials, screen, soak and mix them till you obtain a milky white liquid.

Plant-based milk

<span style="font-weight: 400">Cocoa production and the cocoa industry uses industrial processing technology to process and manufacture high quality cocoa products in many different forms. Did you know that cacao cultivation goes back centuries - to be specific, about 5300 years? </span><span style="font-weight: 400">This plant, with its long history, is also known for its versatile usage. From </span><span style="font-weight: 400">cocoa nips to cocoa butter, cocoa becomes a base to produce multiple products, ranging from food products to cosmetics. As you may already know, chocolate products are all made from cocoa as well. Hence, depending on what you intend to produce as the end product, as well as your recipe, your cocoa processing equipment line may change.</span>

Cocoa

Liquid

Healthcare products are goods or services used to improve, maintain or prevent the deterioration of health or ease the consequences of illness. Healthcare products include a wide range of goods, from hospital clothing, over plasters, wound care products and diagnostic devices. These products must be clean and contamination-free, which is achieved with strictly regulated healthcare equipment.

Healthcare products

Complex processes call for continuous tracking and monitoring systems that help you to keep the manufacturing operation under control. The technology analyzes the components in the production phase for divergence in behavior or changes in conditions. Based on advanced software applications, monitoring platforms make sure that your products satisfy the quality criteria while they are being developed.

Continuous

<span style="font-weight: 400;">An accurate, automated sampling of cultures is a key requirement in the development of biopharmaceuticals. For automated sampling across a larger number of bioreactors, a robust and reliable automated system is needed to accurately transfer bioprocess samples directly to a range of analytical devices while maintaining the highest levels of sterility. For medium-scale operations, a cost-effective and efficient system is required to improve process performance.</span>
<h2>Automated multiple bioreactor sampling</h2>
<span style="font-weight: 400;">The Flownamics Seg-Flow 4800 is a fully automated online sampling solution for up to 8 bioreactor vessels. Using unique FISP cell-free sampling probes, the Seg-Flow can deliver accurate samples to up to 4 analyzers.</span>

<span style="font-weight: 400;">Segmented flow technology allows rapid and accurate low volume samples to be taken from reactor vessels containing aerobic or anaerobic bacterial cultures and yeast, fungi, algae, insect, animal, and mammalian cell cultures. Samples can be either cell-containing or cell-free.</span>

<span style="font-weight: 400;">Rapid and accurate sampling is available for user-defined sample sizes from as little as 250 to 15 ml.</span>

<span style="font-weight: 400;">The internal Flow-Web web server logs data and information for each vessel or stream independently and allows viewing and control from any PC or mobile device.</span>

<span style="font-weight: 400;">The Seg-Flow features a single-use fluid path from the vessel to the analyzer to reduce operating and maintenance costs. The sample line is automatically cleaned or sterilized after each sample. The user-friendly operating system means minimal training is required, and setup is straightforward.</span>

<span style="font-weight: 400;">The Sefg-Flow’s highly flexible operating software can be tailored to your specific applications. It allows data to be saved in spreadsheet format or automatically exported to other software. System status and reporting can be quickly checked from any device with a browser and internet access.</span>

Automatic sampling system for bioprocess monitoring

Biotech equipment is used for cellular and biomolecular processing to develop products that improve our lives and the planet. With the help of specialized lab equipment, the active substance is manufactured or extracted from biological origin materials and typically produced in bioreactors by plant cells, microbial cells, yeast cultures, or mammalian cells. Cell isolation, cultivation, cell banking, and culture expansion are called upstream processes. After harvest, the production process moves into a downstream process to meet purity and quality requirements which is divided into cell disruption, purification, and polishing. Biotechnology equipment makes use of various laboratory machinery such as bioreactors, centrifuges and incubators.

Biotech

Industrial measurement equipment is used as a crucial step before products leave the production line. These measuring instruments check for correct dosage and standards. Equipment for measurement and control employs a wide range of technologies to detect inconsistencies in volumes, sizes, weights, and fill levels as well as to inspect goods for quality against a set of criteria. Specialized measuring tools allow you to minimize the probability for error to its lowest possible, ensuring that both products and packaging meet your benchmarks.

Measurement &amp; Control

Monitoring

Industrial sampling equipment are systems that allow manufacturers to test (in other words to take a sample of) the products they are manufacturing. This process is generally implemented as a means of quality control but it can also be used as a mean to ensure that production processes adhere to certain regulatory standards. Quality control in your manufacturing process starts with precision sampling techniques. Automated systems deliver consistent samples at a pre-set rate for accurate testing and probing. Sampling technology uses a calibration system involving a series of sensors to extract the material at high levels of reliability.

Sampling

liquid

Designed to allow operators to perform sterility testing in an aseptic environment providing assurance of material integrity.


<h2>For ultimate containment of all API and potent compounds, where the containment capability is crucial</h2>
The Half-suit tester from Telstar life-Sciences is the most likely component of the isolator which mission is to suffer wear and tear and thus develop leaks. Due to it works in the critical zone, guarantees special attention at the design stage and when monitoring protocols are developed.

The containment capability of half-suits is therefore as crucial as any other part of the integrated system, and a simple, accessible means of checking interface integrity is critical.

Telstar ACE offers custom-built testing systems to enable fast, easy measurement of half-suit containment efficiency. The Telstar Half-suit Tester is designed to allow both in situ and offline testing.

Half-suit tester

The essential objectives of containment systems are personnel protection and preventing the release of toxic or infectious material into the environment. Containment is also used to prevent a product or sample from contamination by the external environment. In the chemical and pharmaceutical industries, containment solutions are used to protect the personnel from the leaking of airborne particles of hazardous substances, as powders or liquids are handled or transferred during processing.

Containment

Drawing samples and testing them for conformity with preset quality standards allows manufacturing units to produce a consistent quality of the product. In a batch process, sample testing systems ensures that each batch meets the specified standards. In a continuous process, product and materials testing helps in the early identification of quality issues, saving significant time and resources, and preventing a sub-standard product from reaching the market. The selection of industrial testing equipment depends on the identification of key quality parameters. These parameters may include volume, weight, viscosity, hardness, particle size distribution, sterility, gauge and containment, among other parameters. Testing machinery need regular calibration to ensure that the parameters being tested are accurate. Some of the more common testing solutions include thermal imagers, scratch testers, optical inspectors and texture analyzers.

Testing

solid

Features waterproof and dust proof cabinet and components. Its hygienic design is perfect for unpacked and fresh foods which require stringent sanitary control.


<h2>Stringent sanitary control for unpackaged fresh food</h2>
The SSV-i series from Anritsu are waterproof checkweigher with a waterproof and dust-proof exterior. This series of check weighers are designed for unpackaged food. Its hygienic design allows for stringent sanitary control for unpackaged fresh food, such as fish, poultry and other meat products. The waterproof exterior is needed during the cleaning process to ensure that all parts of the checkweigher remain intact and fully operational after being sprayed down and sanitized.

The checkweighing system is not only used for weighing products and checking for missing products, but is also used for controlling filler or fixed weight, data recording and line monitoring.

Waterproof checkweigher

Weighing

Batch

Biopharmaceutical manufacturers are increasingly making use of Single-use pressure sensors to enhance efficiency, make equipment more versatile for use in a variety of processes, and decrease risk of cross contamination. Today even sensing technology enjoys the convenience and maintenance savings of disposable technology.
<h2>Accurate pressure sensing in a preprogrammed, easy set up, disposable package</h2>
Scilog is focused on improving the quality and efficiency of customers’ processes in the bio pharmaceutical industry through enhancements and automation of sensing, filtration and other processing needs.  The company’s SciPres system is single use pressure sensor that is easy to use, pre-calibrated, and ready for plug-and-play integration into your bio pharmaceutical production process.  The sensors are barcoded for traceability, medical grade, and NIST traceable.  They are accurate to +/- .02 bar at maximum allowable pressure of 4.1 bar.

Five sizes are available accommodating flow rates from 1 L/min to 60 L/min.  These sensors are compatible with may commonly used types of sanitation including, NaOH, NaCl, formaldehyde, autoclaving, and gamma irradiation.  Scilog has extensive experience developing single use sensors and these can be found used in a wide variety of bio-pharmaceutical process equipment.  They can also be integrated with the Sci-Pres monitor for stand-alone monitoring of up to three pressure sensor inputs.

Single-use pressure sensor

Biopharmaceutical manufacturers are increasingly making use of single-use conductivity sensors to enhance efficiency, make equipment more versatile for use in a variety of processes, and decrease risk of cross contamination. Today even sensing technology enjoys the convenience and maintenance savings of disposable technology.
<h2>Accurate electrolyte conductivity and temperature sensing in a preprogrammed, easy set up, disposable package</h2>
Scilog is focused on improving the quality and efficiency of customers’ processes in the biopharmaceutical industry through enhancements and automation of sensing, filtration and other processing needs.  The company’s SciCon system is single use temperature and conductivity sensor that is easy to use, pre-calibrated, and ready for plug-and-play integration into your biopharmaceutical production process.  The sensors are barcoded for traceability, medical grade, and NIST traceable.  For conductivity they are accurate to +/- 2.5 mS of full range with range of 1 uS/cm to 200 mS/cm.  For temperature effective range is 4 -50 C with an accuracy of +/- 0.5 C.  Five sizes are available accommodating flow rates from 1 L/min to 60 L/min.  These sensors are compatible with may commonly used types of sanitization including, NaOH, NaCl, formaldehyde, autoclaving, and gamma irradiation.  Scilog has extensive experience developing single use sensors and these can be found used in a wide variety of biopharmaceutical process equipment.  They can also be integrated with the SciCon monitor for stand-alone monitoring and automated documentation using the SciDoc software package.

Single-use conductivity sensor

Biopharmaceutical manufacturers are increasingly making use of single-use temperature sensors to enhance efficiency, make equipment more versatile for use in a variety of processes, and decrease risk of cross contamination. Today even sensing technology enjoys the convenience and maintenance savings of disposable technology.
<h2>Accurate temperature sensing in a preprogrammed, easy set up, disposable package</h2>
Scilog is focused on improving the quality and efficiency of customers’ processes in the biopharmaceutical industry through enhancements and automation of sensing, filtration and other processing needs.  The company’s SciTemp system is single use temperature sensor that is easy to use, pre-calibrated, and ready for plug-and-play integration into your biopharmaceutical production process.  The sensors are barcoded for traceability, medical grade, and NIST traceable.  Their effective temperature measurement range is -40 to 150 C with an accuracy of +/- 0.5 C in the 4 to 70 C range.  Five sizes are available accommodating flow rates from 1 L/min to 60 L/min.  These sensors are compatible with may commonly used types of sanitization including, NaOH, NaCl, formaldehyde, autoclaving, and gamma irradiation.  Scilog has extensive experience developing single use sensors and these can be found used in a wide variety of biopharmaceutical process equipment.  They can also be integrated with the SciTemp monitor for stand-alone monitoring of up to two temperature sensor inputs.

Single-use temperature sensor

<span style="font-weight: 400;">The production of pharmaceutical capsules requires that individual doses are checked for accuracy. In a production environment this also needs to be done at speed. Fast throughput and ease of use are important in a production scale checkweigher.</span>
<h2>High accuracy, easy-to-use weight checkers for a range of production scales</h2>
<span style="font-weight: 400;">The Sejong Pharmatech iW Series of production weight checkers have been specifically designed to give the highest accuracy whilst maximising throughput and simplifying operation and maintenance.</span>

<span style="font-weight: 400;">Available in 4 variants, the iW series is capable of checking 10,000, 60,000, 120,000 or 180,000 units per hour to suit your exact requirements.</span>

<span style="font-weight: 400;">The highly accurate weight cell used offers accuracy of +/-2mg whilst operating at these speeds, and the simple to use touchscreen display provides instant graphical feedback on the performance of the unit. The control system is fully 21CFR part 11 compliant for record-keeping and monitoring.</span>

<span style="font-weight: 400;">Able to handle a range of capsule sizes from #000 to #5, the machine has two output paths, one for pass, one for reject. Optional extras include air conveyor to transport capsules from the pass chute to storage container.</span>

<span style="font-weight: 400;">The machines are top loaded for convenience and feature built-in castors to allow easy movement of location or to access parts of the machine for maintenance and inspection.</span>

Capsule checkweigher

In the pharmaceutical world, encapsulation refers to various techniques to enclose and protect the drug ingredients by forming the capsule shell. Encapsulation equipment changes depending on whether the manufacturer needs to produce a soft or hard gel capsule. For instance, encapsulation systems and machines for softgels control the entire process from start to finish because their shells are filled at the same time they are produced. On the other hand, the filling of hard gel capsules comes by separating the body from the cap, and after the filling operations, the two parts are sealed together again, forming the shell.

Encapsulation

<span style="font-weight: 400;">An accurate and sterile sampling of cultures is vital throughout the biopharmaceutical development process. For constant, accurate monitoring, a reliable automated system is needed that transfers bioprocess samples directly from bioreactors to a range of analytical devices without intervention while maintaining the highest levels of sterility. For small-scale development, the availability of a more cost-effective entry-level system brings large economic advantages.</span>
<h2>Affordable automated bioreactor sampling</h2>
<span style="font-weight: 400;">The Seg-Flow 1200 Automated Bioreactor Sampling System from Flownamics is an economical alternative to the larger Seg-Flow 4800. It is available in two models, the Seg-Flow 1200 and the Seg-Flow 1200 Plus.</span>

<span style="font-weight: 400;">Segmented flow technology allows rapid and accurate low volume samples to be taken from reactor vessels containing aerobic or anaerobic bacterial cultures and yeast, fungi, algae, insect, animal, and mammalian cell cultures. Samples can be either cell-containing or cell-free.</span>

<span style="font-weight: 400;">By incorporating a disposable, single-use flow path, the Seg-Flow 1200 is easy to use and requires little maintenance and no specialist operator training.</span>

<span style="font-weight: 400;">Samples can be collected from up to 2 reactors and delivered to 2 analyzers or collectors. Built-in expansion capability means this can be extended to 4 reactors with the Sample Module.</span>

<span style="font-weight: 400;">Integrated control functions such as an automated feed from an at-line glucose measurement can be quickly and easily implemented.</span>

<span style="font-weight: 400;">The Seg-Flow 1200 can be used with small laboratory vessels right up to large full-scale production vessels with 12, 19, and 25 mm models.</span>

<span style="font-weight: 400;">The unique Flownamics FISP filter probe used in the Seg-Flow 1200 ensures a sterile, cell-free sample can be taken from any vessel.</span>

&nbsp;

Entry-level automated online sampling system

Formulation technologies are an integral process in many industries such as pharma and food. Chemical mixtures require strict handling to combine the separate ingredients into the homogenized recipe that makes your final product. Formulation technology stores, mixes and subjects the elements to a range processing parameters according to your specifications to develop the base material. The resulting formulas are then weighed, formed, packaged, or sent for further formulation.

Formulation

<span style="font-weight: 400;">Accurate sampling is vital for improving a wide variety of industrial, chemical, and biofuel processes. A sampling solution that provides  24/7 automated, real-time analyte monitoring, fraction collection, feed control, and data processing will allow increased process performance and development to maximize performance.</span>
<h2>Automated sampling for up to eight vessels</h2>
<span style="font-weight: 400;">The Flownamics Seg-Flow 8000i is a fully automated online sampling system that offers multiple process monitoring and control solutions designed for biofuel, chemical or industrial processes.</span>

<span style="font-weight: 400;">The Seg-Flow’s patented segmented online sampling technology means rapid and accurate sampling for up to 8 vessels and sample delivery to up to 4 analyzers and/or fraction collectors. It uses a chemically inert fluid path with automated cleaning or sterilizing after each sample. </span><span style="font-weight: 400;">A number of feed control options are available for maximum flexibility, and the Seg-Flow 8000i can control up to 2 pumps per vessel.</span>

<span style="font-weight: 400;">The 8000i is scaled independent and can be used with laboratory, pilot, or production vessels. It utilizes the unique FISP in-situ sampling probe, which provides an aseptic barrier between the vessel and the Seg-Flow system. </span><span style="font-weight: 400;">The Seg-Flow features a built-in touchscreen HMI, providing control over many samples and feed options. The easy-to-use system requires minimal training and allows parameters to be programmed within minutes.</span>

<span style="font-weight: 400;">The internal Flow-Web web server logs data and information for each vessel or stream independently and allows viewing and control from any PC or mobile device.</span>

<span style="font-weight: 400;">Sefg-Flow’s highly flexible operating software can be tailored to your specific applications. It allows data to be saved in spreadsheet format or automatically exported to other software. System status and reporting can be quickly checked from any device with a browser and internet access.</span>

Online sampling system for larger scale bioprocesses

<span style="font-weight: 400;">Accurate, sterile sample collection is vital across a range of biopharmaceutical, chemical, and industrial processes. To eliminate the risk of contaminating either the culture or the sample, specially designed probes developed to withstand fermentation environments can deliver accurate, cell-free samples for monitoring and development.</span>
<h2>Risk-free sampling for use with bioreactor side ports</h2>
<span style="font-weight: 400;">The Flownamics FISP D-Series is a dedicated sampling probe capable of withdrawing sterile, cell-free samples from fermenters and bioreactors with 25mm side ports from lab scale up to production.</span>

<span style="font-weight: 400;">At the heart of FISP is a fully sterilizable carrier that’s encompassed by a specially designed micro-porous membrane. This has been designed to cope with the most extreme fermentation environments, and it’s ideal for use with anaerobic and aerobic bacterial cultures, yeasts and fungi, and mammal and insect cells.</span>

<span style="font-weight: 400;">With a 0.2 micron filter, FISP’s sterile barrier means zero-risk samples can be taken. Its robust design also means it can easily be used to add media or feeding of cultures. </span><span style="font-weight: 400;">FISP is simple to use and requires no additional operator training. It’s also simple to sterilize and can be used as an autoclave and</span><span style="font-weight: 400;"> manual sampling process. FISP is fully compatible with the Seg-Flow range - Flownamics’ automated sampling products.</span>

Sampling probe suitable for fermenter samples

<span style="font-weight: 400;">For many bioprocesses, precise measurement of media flow rates is vital to process monitoring, additive delivery, filtration, sample delivery, and more. The use of a highly accurate automated flow rate measurement system that is also capable of controlling pumps can bring significant advantages to delivery quality and accuracy across processes.</span>
<h2>Accurate flow rate measurement and automatic pump control unit</h2>
<span style="font-weight: 400;">The Flow Reader from Flownamics is a highly accurate fluid flow rate sensor and pump controller.</span>

<span style="font-weight: 400;">Flow Reader features a patented dual sensor technology for outstanding accuracy down to as low as 0.01ml/minute.</span>

<span style="font-weight: 400;">The sensor operates by using sterile air bubbles injected into the fluid path. By tracking the leading edge of the bubble through a known volume past two discrete sensors, a high accuracy reading is obtained.</span>

<span style="font-weight: 400;">The read tube is gamma radiated and disposable and can be welded directly into your fluid path if required. </span>

<span style="font-weight: 400;">Flow Reader is then able to provide feedback to any pumping system capable of receiving 0-10V control inputs, including the Flownamics FP-101, eliminating the need for recalibrations.</span>

Fluid sensor technology for flow rate measurement

Accurate sampling is a critical tool in the design and improvement of a large range of pharmaceutical bioprocesses. For maximum performance you need a robust and highly accurate automated sampling solution that delivers samples to your analysers 24/7 in real-time and can integrate with a large range of instrumentation.
<h2>Automated on-line sampler with increased reliability and ease of use</h2>
The Seg-Flow S3 from Flownamics is the latest generation in their line of automated samplers and has been built to deliver the perfect sampling solution for your most critical processes.

Designed for heavy-duty use, the Seg-Flow S3 has been engineered with increased robustness, featuring a highly durable powder-coated heavy-gauge steel construction. The integrated touchscreen GUI is bright and easy to use, with simple thumbnail navigation, and ideal for any lab environment. Bright LED lights offer “at a glance” status indication for easy monitoring.

Seg-Flow S3 offers complete flexibility to match your sampling needs. It can simultaneously sample from between one and eight vessels or process streams with cell-free or cell-containing samples, and then deliver to up to four analyzers or fraction collectors.

The S3 will automatically clean and/or sterilize the sample lines after every collection, removing cross-contamination risk entirely.

For process monitoring, the S3 can export data to any OPC-enabled DCS, PLC or PC, allowing easy performance data monitoring and analysis.

A wide range of feed control strategies can be programmed into the sampler, including setpoint and gravimetric. The S3 can control 2 feed pumps per vessel.

Fully Automated On-Line Sampling for Bioprocesses

Comprehensive upstream data acquisition and management are essential in the bioprocessing industry. That’s because you can’t be completely sure which historic information you may need in future. SCADA monitoring systems were not designed for laboratory precision. Research work needs more focussed information.


<h2>An Information System for All Stages of Bioreactor Operation</h2>
Lucullus PIMS bioreactor software from Getinge Applikon records the entire process from recipe planning through to automatic reporting and modelling. Phases covered between these points include reactor allocation, experiment design, media preparation, media component traceability, data analysis, and data mining.

This all-embracive approach is time-saving because all information is in a central Oracle database. There’s no need to export and import data between systems. Updating is a thing of the past because you always have the latest version at hand. Moreover, the same software produces accurate spreadsheets and graphs.

Advanced software is necessary to convert data from parallel bioreactor systems into useful information. Data management is key to research and process development in the pharmaceutical industry.

Bioreactor software

A typical pharmaceutical production handles numerous work flow activities like management of assets, shifts, shop floor activities, production scheduling and process orders. Quality control, track and trace and supply chain are the key production control tasks. Currently, the data required to control production is stored at different locations in the company's database, making it difficult to integrate all processes. A single centralized platform incorporating all production operations optimizes processes and maximizes production efficiency.


<h2>A complete database management system for pharmaceutical production line</h2>
Yudoo from SEA VISION is a multi-module advanced software suite that aids the pharmaceutical industry evolve from traditional production to smart digital manufacturing. It integrates numerous pharma production applications into a single platform. A centralized batch production management system monitors the work flow in real-time. Production activities for start/stop, selecting machines, cleaning, format change and printer template are controlled on lines and systems on the manufacturing site.

The system offers a comprehensive set of tools for managing all the pharmaceutical quality standards compliant with the current regulations. Sensors kits installed on the machine gather alarm signals and digitalize the data. Short- and long-term historical data collected makes way for performance analysis and monitoring. An intuitive interface prompts operators for their everyday tasks. The system also enables shift management, involving teams and assets integration. Assigning of teams to shifts helps identify inefficiencies, improves shift management and overall team performance. Role-based management guarantees that the correct individuals have access to the right information at the right time. The system integrates various tools to manage track and trace configuration and maximize the efficiency of serialized pharma production lines. It enables communication with the company's ERP or MES, as well as other cloud-based systems for total centralized control.

Pharmaceutical data management software

For accurate comparisons of carbon conversion rates and yields for six simultaneous anaerobic fermentations.


<h2>Very accurate characterization of the fermentation quality</h2>
The Anaerobic Fermentation Monitor from Getinge Applikon is a robust and user-friendly laboratory parallel bioreactor that allows for accurate comparisons of carbon conversion rates and yields for six simultaneous anaerobic fermentations.

It serves not only as the perfect screening machine for general research on anaerobic yeast fermentations, but also as a powerful, time saving tool for plant design and process optimization. A very accurate characterization of the fermentation quality can be obtained, without the need for highly educated laboratory staff, which is an important, money saving feature.

Anaerobic Fermentation Monitor

The fermentation process stimulates enzymatic activity in organic substrates to transform their chemical composition. Fermentation is aided by storying the biomaterials in anaerobic environments, allowing the microorganisms to decompose their nutrient structures. The process is integral to some of the most popular products throughout time such as wine, beer, cheese, and kimchi. But besides the food sector, fermentation is also an important stage in the industrial manufacturing of chemicals, pharmaceuticals, and biofuels.

Fermentation

Success with bioprocesses is all about controlling the environmental conditions controls so you can replicate processes consistently. Good insight and easy adjustment of pH, Temperature, Dissolved Oxygen, Foam/Level and Agitation are crucial for any biopharmaceutical process.


<h2>Easy to use control for lab scale operation</h2>
The ez2-Control from Getinge Applikon is an easy to use control and measurement system for bioreactors and fermentors. The bioreactor control system offers high accuracy, a good insight and easy adjustment of pH, Temperature, dissolved Oxygen, Foam/Level and Agitation, which are crucial for any biopharmaceutical process.

The colour touch screen interface guides the user through the operation.  The adaptive control features allow the user to focus on the process while the controller keeps tight control on the important process parameters.

The new web-interface for ez2-Control with advanced user management option provides a clear overview of the bioprocess parameters. Also it allows back-ups, copies and predefined settings of configurations to be simply shared via USB.

The ez2-Control can be used to control a large variety of reaction environments: From autoclavable bioreactors, steam in place bioreactors, to Appliflex single use bioreactors, milipore Cell Ready single use bioreactors or HyClone SUB bioreactors.

Lab scale Bioreactor controller

When you are working with small bioreactors, starting from 50 ml volumes, you need a good insight and an easy adjustment of pH, Temperature, Dissolved Oxygen, Foam/Level and Agitation.


<h2>Control system for small-scale bioreactors</h2>
MyControl from Getinge Applikon is the most advanced controller available for small-scale bioreactors, compatible with bioreactors ranging from 50 mL to 2,700 mL (working volume), and is easily convertible between microbial and cell culture configurations.

The built-in software interface allows you to access with a web browser via computer, tablet or smartphone, so you can manage your entire laboratory with ease.

It is pre-configured and ready to use. Adding additional control loops, sensors, actuators, or external I/O is also fast and easy, so you will receive a system that meets your exact process specifications! Moreover, it is modular, so you can change your configuration options in the future as your experimental objectives.

One control system can control: 250 ml up to 1000 ml MiniBio bioreactors, 1L up to 3 liter Autoclavable bioreactors, 3 liter Cellready single use bioreactors.

Small-scale bioreactor controller

When you are up-scaling bioprocesses, starting at the lab and going all the way to the pilot and production scale; a scalable can come to represent a compelling solution to have. The required system has to allow a large number of inputs and outputs, synoptic displays, trending screens, alarms and much more.


<h2>Pilot scale to production bioreactor control system</h2>
Getinge Applikon i-Control is an easy-to-operate Scalable bioreactor controller and utility console. This scalable control solution is used to control processes in bioreactor systems from laboratory scale to pilot plant and production scale. The i-control from Getinge Applikon is a human interface color touch screen device used to control the most important parameters at a laboratory scale scenery.

The seamless scale-ability saves time and money by offering a simple scale-up of a control strategy from research via pilot-plant to production. The simplicity of operation is one of the key features, allowing operation by cell biologists, and configurations to get adapted to changing process demands without the need of an engineer on-site.

Scalable bioreactor controller

The vast majority of all biotechnological processes are aerobic, where a microorganism or cell responds to the liquid phase oxygen concentration in regulating its overall metabolism. Knowing the exact oxygen content in the working atmosphere is critical for your process.


<h2>DO2 Sensor optimized for bioprocesses</h2>
The Dissolved Oxygen sensor is a measuring device that informs about the dissolved oxygen in biotechnology processes, which is a basis for process optimization and control.

The AppliSens Low-Drift DO2 sensor from Getinge Applikon is specifically designed for long-term, stable, and accurate measurements in bioprocesses, such as fermentation and cell culture applications. Designed to withstand repeated sterilizations without failure.

The DO2 sensor has a titanium membrane module to minimize the measurement drift, and the available autoclave polarization module allows you to reduce start-up time for your cultures.

Dissolved Oxygen sensor

pH is one of the most important parameters of cell-culture and fermentation processing in the biotech industry. New technologies are emerging that warrant accurate measurement and improve durability even in high-temperature steam-sterilization processes.


<h2>Acidity sensor optimized for bioprocesses</h2>
The pH sensor from Getinge Applikon is constructed using FDA approved materials, like the non-toxic solid gel electrolyte. Furthermore this sensor has an internal pressure, which reduces cross contamination. The pH sensor is designed to withstand repeated sterilization cycles without failure.

pH Sensor

A Laboratory air jet sieve is used for determining the particle size distribution of powdery and granular materials.


<h2>Intuitive analysis of particle size distribution</h2>
The e200 LS from Hosokawa is ideal for analyzing any kind of dry material. Samples of between 0.3 and 100 grams in weight can be analyzed easily and quickly. The batch weight is dependent on the sieve mesh width and material density. The extraordinarily good dispersion of the material being analyzed by the nozzle jet permits analyses down to 10 µm with the micro-precision sieves.

The only thing that moves the material being analyzed is the airflow. This system makes it possible to do without any and all mechanical means of influencing the sieving process of different materials, such as non-organic or organic granular materials including sands, crushed rock, clays, granite, feldspars, coal, soil, a wide range of manufactured powders.

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Laboratory air jet sieve

Industrial separation equipment encapsulates the separation process which is to separate components of a liquid mixture, for recovering dissolved solids from liquids. The choice of a suitable technology depends on the identification of the key physical or chemical property, such as size, mass, density, or boiling point, which sets the product of interest apart from the rest of the components. Separation technology is widely used in the pharmaceutical and chemical industries for the isolation of active ingredients and high-purity chemicals. As well as in waste management and recycling industries.

Separation

Sieving machines are available in various designs such as linear sieves, tumbler sieves, and vibrating sieves each employing a different sieving action. The choice of a suitable sieving machine depends on the desired particle size distribution, required amplitude and frequency of vibrations, and the physical state of the mixture. Sieving machines are used for removing dust from granular products and for grading grains. They are also used for the classification of granular material and the separation of solids from a slurry mix in the food processing industries.

Sieving

When you want to predict powder behavior in future and existing installations, possible measures to be taken or for standardized product quality control for incoming goods, you need a good Powder tester.


<h2>Measure flowability and floodability of your powders</h2>
The Powder Tester PT-X from Hosokawa Micron is used to determine the flowability and floodability of dry powders. The model PT-X is the latest design of the Hosokawa Micron Powder Characteristics Tester which utilizes state-of-the-art features to identify the specific characteristics of powdered samples for a wide range of application fields.

Powder tester

Testing device of the containment capability of gloves, which is as important as the other parts of the integrated system; and a simple, accessible means of checking interface integrity is critical.


<h2>Testing system to enable fast, easy measurement of glove containment efficiency</h2>
Glove Tester from Telstar Life-Sciences is a low cost manually operated single port testing device designed to allow both in situ and offline testing.

Constructed of acetyl or 316L stainless steel, the device uses air pressure to check glove integrity. It can be designed to suit all types of Telstar ACE glove ports as well as other port brands. The tester inflates the glove at +500Pa pressure for a period of at least five minutes. A leak is indicated by a drop in the pressure reading of the display gauge. An optional colour indicator gives an instant pass/fail assessment.

Glove tester

The checkweighers for multiple lanes have a 1.5 times faster response speed and 2 times higher accuracy than conventional models with the high-rigidity electromagnetic balancing weigh cell.


<h2>Specialized multi-lane check weighing system</h2>
The checkweigher for sachets and sticks, from Anritsu is a specially multi-lane check weighing system, utilized to weigh individual packages that are in small stick shapes, like individual water bottle flavour packs. Most of the products consist of granulated sugar. The stick pack weighing system consists of the KW6023F type, available in six different models. All the models have weighing control of up to six lanes with just one indicator.

Checkweigher for sachets and sticks

Control the quality of your pelletizing processes using a pellet hardness tester. Pellet hardness is one of the most critical characteristics indicating process quality, and it is essential to ensure a desirable product and efficient downstream processes. The hardness can now be measured right after the pellets have left the cooler.
<h2>Monitor your pelletizing process with a hardness tester</h2>
Amandus Kahl’s pellet hardness tester is a hand-held device that allows the user to quickly and easily monitor the quality of their pelletizing process at the source without the need for laboratory equipment. Hardness/softness is a good measure of overall pellet process quality. Using this device allows the customer to test pellet softness and immediately adjust the process parameters to achieve the desired results without delays and lost production time caused by waiting for more sophisticated laboratory equipment.

The pellet hardness tester allows a simple in-the-field quality control for the pelletizing process. The pellet tester comes in two versions, manual and automatic. An operator can periodically rotate the adjusting screw on the manual version at different speeds to retrieve multiple readings. The automatic unit is motorized and works independently, offering more consistency and better comparison of the hardness values taken by different operators due to potential variation in operator handling of the manual version.

Pellet hardness tester

Pelleting equipment transforms powdered, mashed, or grounded material into a denser cylindrical shape. Pellet processing compresses the fine material against a perforated die, where it will be shaped and cut. Although granulating and extrusion also produce pellet-like products, manufacturing pellets is a distinct process.

Pelleting

Single use bags for biopharmaceutical process containment and liquid storage are being used with increasing frequency in the industry due to their convenience, efficiency, and inherent cleanliness.  Integration of single use bags into biopharmaceutical processes is a great way to reduce required maintenance, and improve the versatility of equipment without increasing risk of cross contamination.
<h2>A mobile, vertical bag holder with integrated scale compatible with bags from any manufacturer</h2>
Scilog is focused on improving the quality and efficiency of customers’ processes in the biopharmaceutical industry through enhancements and automation of sensing, filtration and other processing needs. The company’s WeighStation system is a wheeled bag stand that works with single use bags from any manufacturer.  The system includes integrated load cells and local display which allow it to be used as a stand-alone scale or to be integrated into other Scilog processing platforms for metered dispensing and purification.  The system has a minimized footprint and superior mobility when compared to a traditional floor scale.  The mobility and use of single use bags allow this piece of equipment to support several processes in your facility rather than being dedicated to just one.

Bag holder and weighing platform for bioprocesses

Purification is the removal of contaminating substances and by-products to increase the level of purity of the desired substance. Considerations for choosing a suitable purification system in the industry, include the physical state of the mixture, the desired product, required level of purity, the type of mixture, heat sensitivity of the product, number of purification steps needed, and the production volume. Industrial purification systems are used for the production of pure water in the food pharmaceutical and biotech industries.

Purification

Pharmaceutical manufacturing demands the highest quality standards and completely consistent production.  Weight variation; however, is a reality of any large-scale production process.  For this reason the industry needs a highly accurate, means of weighchecking production capsules designed for a high volume pharmaceutical manufacturing environment.


<h2>A highly accurate, continuous check-weigher for pharmaceutical capsules</h2>
The Accura checkweigher for capsules from ACGE use an Elector-Magnetic Force Restoration load cell and the latest digital technology to ensure highly accurate capsule weighing for continuous pharmaceutical production.  Capsules in any state:  empty, filled, or partially filled, can be weigh-checked at a rate ranging from 40,000 to 200,000 capsules per hour depending on the Accura model used.

Weight accuracies of +/- 2mg are achieved with the standard units for capsule weights from 20-150mg.  An optional enhancement is available to improve accuracy to +/- .2mg when it is required.  Output data is recorded digitally and can be reported to a plant QA system via USB, Ethernet, or paper printouts.

Industrial capsule checkweigher

<span style="font-weight: 400">At last, you reached the final stage of processing your product - welcome to the packing world! Packing preserves and protects a product from damage, spoilage, and contamination while it makes its way from the production line to the consumer or further production. Depending on which industry your products belong to, the type of primary packaging equipment can change drastically. You need to pay careful attention to products with </span><span style="font-weight: 400">chemicals or hazardous substances since they can be potentially dangerous to human health. </span>

Packing

When designing new lines or new product - or looking for improvements in existing ones - testing the impact of cooling on chocolate quality with traditional methods is costly and time-consuming. You can now simulate your line's cooling tunnel and it's impact on the product as well as a full range of chocolate quality tests. This chocolate analyzer will take your production to the next level.


<h2>Simulate your production line to help improve or maintain your chocolate quality</h2>
The ChocoAnalyzer from Aasted provides you with invaluable data to be able to adjust your tempering machines and cooling tunnels to gain maximum contraction. More than just a quality assurance tool, the ChocoAnalyzer gives you the information you need to improve existing production and research new lines.

Developed by Aasted in collaboration with leading scientists from AAK, the ChocoAnalyzer allows you to investigate the difference in tempering quality on various equipment, measure how fillings expand or contract in relation to the chocolate and simulate your cooling tunnel process so see its effects on contraction profile.

The ChocoAnalyzer offers many more measurements and testing possibilities than a standard tempermeter, and has a bespoke sample reactor with brand new probe designs to deliver the most precise results currently available.  The built in printer can quickly produce hard copy of test results and data can easily be exported by USB or ethernet as csv files. The unit has been designed to be easy to use, with a familiar "app" style interface designed for use by non-technical staff.

Chocolate analyzer

<span style="font-weight: 400;">Many bioprocesses require offline analysis of samples to monitor development and optimize performance. By using an automated fraction collector, the collection process can be accelerated and delivered with increased accuracy. Compatibility with automated reactor samplers is vital.</span>
<h2>Collect fractions from reactor vessels automatically</h2>
<span style="font-weight: 400;">The Flownamics FlowFraction is used in conjunction with the Flownamics Seg-Flow sampling systems. It allows the online collection of fractions from up to eight reactor vessels for further offline analysis of a range of bioprocesses.</span>

<span style="font-weight: 400;">The FlowFraction system is customizable to accommodate various tube types and sizes and can sample volumes from 250 µl to 50 ml. An added benefit is that vials can be equipped with a septum as a piercing option is available. For storage, racks in a range of standard sizes can be shipped with the FlowFraction, but custom rack sizes can also be produced to meet exact requirements.</span>

<span style="font-weight: 400;">A range of advanced options can be specified to meet your requirements perfectly, including temperature control modules featuring Peltier or water-based cooling systems. Using the options Seg-Flow Sample module, sample dilutions, and reagent additions can be performed before vial deposits.</span>

<span style="font-weight: 400;">Thanks to the included Flownamics WebFlow software, the interface allows easy control and data capture with minimal operator training. Maintenance time is reduced thanks to all internal fluid paths being self-cleaned after each sample.</span>

Online fraction collector for offline bioprocess analysis

<span style="font-weight: 400;">In biopharmaceutical and chemical industries, sampling is vital to develop, maintain, and improve processes. This needs to be done in aseptic conditions. The risk of contaminating either the test sample or the reactor can be eliminated by using a dedicated sampling probe designed to operate with the range of sample ports in use across all scales of production.</span>
<h2>Risk-free sampling for use with bioreactor top ports</h2>
<span style="font-weight: 400;">The Flownamics FISP F-Series is a dedicated sampling probe capable of withdrawing sterile, cell-free samples from fermenters and bioreactors with 12mm or 19mm top ports from lab scale up to production.</span>

<span style="font-weight: 400;">FISP is a sterilizable 316 stainless steel carrier that is surrounded by a tubular, microporous membrane.</span>

<span style="font-weight: 400;">FISP has been designed to withstand the temperatures, pressures, and chemicals found in fermentation environments and is perfect for aerobic or anaerobic bacteria, yeast, fungi, algae, insect, and mammalian cell cultures. Its design provides risk-free sampling thanks to a sterile barrier provided by its 0.2-micron filter. It offers the flexibility of being able to be used for submerged feeding or adding sterile media.</span>

<span style="font-weight: 400;">Compatible with Clean in Place (CIP), Sterilize in Place (SIP), and autoclaving, the FISP is easy to maintain and intuitive to use, with no specialist training required.</span>

<span style="font-weight: 400;">The FISP has been developed to work seamlessly with the Flownamics Seg-Flow range of automated samplers for use in fully automated test scenarios.</span>

Sampling probe for bioreactor samples

<span style="font-weight: 400;">Advanced biopharmaceutical and lab systems involving microcarrier and stem cell applications require daily media changes. This carries the risk of contamination and of cells leaving the reactor or detaching from their microcarriers. A dedicated and flexible system to achieve complete filtration will improve the efficiency and eliminate the risks in perfusion operations at any scale.</span>
<h2>Highly flexible small-scale perfusion controller</h2>
<span style="font-weight: 400;">The PMR system from Flownamics utilizes FISP probe technology for aseptic media removal from any size of bioreactor. With PMR, cells never leave the reactor.</span>

<span style="font-weight: 400;">FISP probes in combination with a patented dual fluid sensor pump control offer the ideal in-situ </span><span style="font-weight: 400;">perfusion system for small scale reactors at a low cost.</span>

<span style="font-weight: 400;">PMR only requires 100ml of total working volume in the reactor thanks to the minimal dead volume in the FISP probe. This is ideal for smaller scale or lab work because other perfusion systems typically require a much larger volume to operate.</span>

<span style="font-weight: 400;">The PMR system is perfect for advanced processes involving microcarrier and stem cell applications that require frequent media exchanges, providing an in-situ filtration solution that keeps cells in the reactor and attached to their microcarriers.</span>

<span style="font-weight: 400;">A web-based user interface provides complete control over flow rates (independent control over addition and removal pumps) from 0.1ml/min to 50 ml/min.</span>

Perfusion process controller

<span style="font-weight: 400;">In many biopharmaceutical or chemical development processes, lab work can be greatly enhanced by the availability of small form-factor, high-reliability accessory feed pumps purpose-designed for reliability and accuracy.</span>
<h2>Flexible, compact feed pump for lab environments</h2>
<span style="font-weight: 400;">The Flownamics FP-101 is an accessory feed pump that has been designed to be used with a wide range of applications such as automated bioreactor feedback control, continuous set point control, or manual feed additions.</span>

<span style="font-weight: 400;">The FP-101 has a 114DV flip-top four-roller pump head, which makes installing tubing quick and easy, saving time with setup.</span>

<span style="font-weight: 400;">Measuring only 9.5cm x 12cm x 16cm and weighing just 600g, this small-footprint pump is ideal for already crowded benchtops.</span>

<span style="font-weight: 400;">Enhanced features include one-button priming, user-set manual speed control via easy-to-use dial, or fully automatic remote control using 0-5V input.</span>

<span style="font-weight: 400;">FP-101 can be used with tubing from 0.5mm to 4.8mm internal diameter, and flow rates can be controlled from 0.1ml/min to 150ml/min</span>

Accessory feed pump for various applications

Managing serialization data is a vital part of accurate reporting and product integrity in the pharmaceutical industry. Current systems require a cascade of servers from line level to site level and up to corporate level. Usually supplied by different vendors, interfaces are required between all these systems which can introduce integrity issues as well as adding complexity. An all-in-one solution can overcome these challenges and provide a “single source of truth” for all data.
<h2>Cost-effective cloud solution for whole-organisation integrated serialization management</h2>
The Amacena System from Hicof is a completely integrated single system for managing serialization data across your entire business.

The system is a cloud-based subscription model which offers substantial cost benefits as well as redundancy. There is also an on-premises client-server option where this may be preferred.

Key benefits to pharmaceutical producers include the data integrity and streamlining benefits of operating a single vendor system from levels 1 to 4 across the business, ensuring data integrity at all stages.

Amacena allows fully GMP compliant Master Data Management, providing a single source of truth for data across the organization.

Cloud technology allows full integration with external partners on a global scale, including regulators, contract manufacturing organizations and marketing authorization holders.

By offering three installation and operation options, the system can be completely tailored to your exact requirements - full cloud, hybrid, full on-premises.

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Serial Data Managing Database

For lab work or small batch production, hand counting of solid doses into dispensing containers is the most common method used. However, hand-counting is slow and can be inaccurate. A dedicated electronic counter with high speed and accuracy is the perfect solution to eliminate delays and errors caused by hand counting.
<h2>Automatic counter for hard doses including tablets, capsules and softgels</h2>
The CPE 6 Electronic Capsule Counter from Multigel is an efficient and accurate counter for a wide range of doses, including tablets (round and oblong), hard capsules, softgels, and other similar dosage types.

The CPE 6 is able to handle a wide range of sizes, making it very flexible. It can accurately count solid doses between 5mm and 25mm diameter and up to 20mm in thickness.

Featuring a simple-to-operate touchscreen interface for ease of use, all aspects of the CPE 6 operation are designed to meet GMP regulations. All parts in contact with the doses are constructed of AISI 316 stainless or other FDA-approved materials and are easily removed, making cleaning quick and simple.

For the elimination of static electricity, the distribution disk is made from crystal. This reduces downtime associated with counter-sensor cleaning caused by dust build-up. When used for counting tablets and optional sieve tray and suction system is available for maximum dust extraction.

Electronic capsule counter

Counting

Managing a large number of bioprocesses individually without automation is time-consuming, and there are possibilities of errors. Bioprocess control software moves this activity to the desktop and creates an activity log.


<h2>Bioprocess Control Software for R&amp;D Scale Bioreactors</h2>
Getinge Applikon’s V-Control bioprocess-control software is a scaled version of Emerson’s proven distributed control system. It simplifies process control, and data upscaling on a single platform. Moreover, organizations already using the DeltaV DCS at production scale have reliable, scaled information that’s easily transferred.

V-Control provides a turnkey solution that customizes to different situations. It has a user-friendly interface, and uses simple technology to minimize upscaling risks. Its easy-going technology and data transfer capabilities may reduce development costs and time-to-market.

This system is therefore ideal for a user wishing to compress start-up time, and work within an optimized DeltaV environment perfected for laboratory bioreactor systems. It is sufficiently flexible to accommodate a wide range of requirements. All hardware and software are pre-configured and ready to switch on.

Bioprocess control software

Having a reliable and accurate weighing and measuring solution is absolutely essential, especially in the pharmaceutical industry to maintain ingredient dosage quality. If you have a rather small production plant, you need a compact and ergonomic weighing scale to help increase efficiency.


<h2>Save costs with a more flexible weighing scale</h2>
Alba’s mobile scale is an industrial scale allowing a great amount of flexibility. It requires minimal space compared to floor scales as one mobile scale can be a substitute for several floor scales. It is very precise and can take load capacities of 30, 60, 100 and 150 kg. It is battery powered with a simple and convenient configuration making it easy to move around while working safely.

Hygienic mobile scale

Dosing systems are a line of hoppers, feeders, filling machines, and checkweighers that operate in sync to dispense materials accurately. Dosing is an essential feature of the packaging process, whether you’re filling shampoo bottles or tea bags. But dosing equipment is critical for formulations, too, particularly in the pharmaceutical and chemical industries. Imprecise dosing may cause quality degradation in the best-case scenario. In the worst scenario, it creates serious health risks.

Dosing

The food and pharmaceutical industries require maintaining high levels of sanitation as well as logistical quality. This entails frequent cleaning of weighing equipment to meet the required standards. You thus need a scale that is reliable, not too bulky while being easy to clean and maintain.


<h2>Simple and effortless cleaning of scale platform</h2>
Alba’s floor scale with lifting mechanism is configured for industries with high sanitary requirements. It is a simple, reliable calibration and extremely user-friendly weighing solution. It is equipped with a ramp which makes loading and unloading of the products very easy. It has a wide loading capacity ranging from 300-1500kg. Its readability is 50g, 100g, 200g and 500g. It can weigh products with 1000 x 1250 mm dimensions but is also customisable according to your needs.

The hygienic floor scale with lifting device makes cleaning of the scale extremely simple. Its lifting mechanism enables a quick and safe elevation of the weighing platform to enable cleaning below it. It can be used at any point in the production process of food and pharmaceuticals where reliable measurement accuracy and hygiene is required.

Hygienic floor scale with lifting device

The food and pharmaceutical industries require maintaining high levels of sanitations as well as logistical quality. The lifting equipment used in these industries thus need to be cleaned thoroughly and very frequently. You thus need a weighing scale that is both accurate, while being easy to move and maintain.


<h2>A flexible and easy to clean lifting scale solution</h2>
Alba’s Floor Scale Moveline is an upgraded version of their standard lifting model. It is a floor scale which makes the raising and repositioning of materials extremely effortless. It is equipped with a ramp to ease loading and unloading of materials. It has a load capacity of 300-1500 kg and can be customised to suit the dimensions of your products. It is also equipped with a free-standing platform. It is a simple and user-friendly scale which is easy to move giving you more flexibility to make the work process more efficient. It can be used at any point in the production process of food and pharmaceuticals where reliable measurement accuracy and hygiene is required.

Hygienic floor scale

No two insect farms are the same and so, each facility requires a modern and tailored solution to operate successfully and more effectively. This is where the help of software can greatly benefit farms by minimizing risks while allowing them to replicate success. The benefit of such software is that they help to make data-based decisions so every batch can deliver better results.


<h2>Tailored insect farm tracking and management software</h2>
Cogastro has developed an insect farming software that provides a modern, flexible, and sophisticated tracking and management solution that can save you time through employee daily tasks automation, recording and measuring farm performance, and help you with control of operations.

Thanks to its infrastructure and cloud-based technology, Cogastro can integrate with different providers and equipment manufacturers and send data to its standard interface through protocols and API and bring together all relevant information such as insect life cycle and feedstock usage in one place.

Additionally, the Cogastro software allows for full-cycle tracking and traceability that will help you for not only being regulatory compliant but providing insight on future production rates and capacity.

Explicitly designed for insect farms, Cogastro’s insect farming software is easy to use, understand, and adapt to your existing farming processes.

Insect farming software

Products like granules, tablets and capsules require inspection at numerous steps in the production and packaging process. Since all pharmaceutical and chemical manufacturers have to follow standard quality specifications, automatic visual inspection, measurements, real time reports, statistical data and control are crucial at various stages of production and packaging.
<h2>Visual inspection and measurement of pellets, granules and mini tablets</h2>
Patvis APA by Sensum visualizes, measures and diagnoses quality of various particles, such as pellets, granules, and mini tablets in real-time when mounted on the process equipment. It consists of a high-resolution camera which performs non-destructive acquisition of live images. These images can be saved for later analysis and research purposes or are analysed in real-time, where the image analysis software programs ensure accurate measurements of particles. Furthermore, it is programmed to monitor and control the quality of particles in accordance with FDA and GAMP. It can detect variations in size, shape and extent of agglomeration during pellet coating, granulation and pelletisation processes. With its graphical user interface various statistical reports can be obtained during and after the process.

Particle analysation monitor

Granulation

Industrial inspection equipment is used for checking compliance with health, safety, and quality control standards. For that reason, inspection systems are most commonly utilized in the food and pharmaceutical industry but, they are also used in other industries too. Inspection solutions are often integrated into a production process or production line. Visual inspection systems perform checks to detect variation in size, shape, and color and ensure the presence of labels and closures. Check-weigh systems help ensure that product packages are not under or over-filled. Metal detection systems can help guard against the presence of foreign objects in product containers and X-ray inspection equipment is used to detect physical defects and to ensure high quality package seal integrity.

Inspection

Milling machines are used to reduce the size of material by cutting, crushing, or grinding it. The choice of industrial milling equipment depends on the industry and the materials to work with. Besides, there is a significant difference between those aimed to remove layers from metal or other materials workpieces and those designed to reduce particle size for materials that come in bulk.

Milling

Each variety of seed has its optimum growing conditions including temperature, lighting, and day and night cycle. If any of these conditions are not correct, the growth process can be compromised. For example, if heat is applied to the seedlings as it breaks the surface, germination can happen too quickly. Using a germination cabinet that lets you test the seed germination by adjusting the conditions accurately can help you understand how to prevent this from happening.

<h2>Applying Heat and Light for the Germination of Seeds</h2>
The QGM-4000 Seed Germination Cabinet from Seed Processing Holland is a seed germination system that can provide an ideal environment for germination process. The germination cabinet is suitable for performing germination tests in research and development. It can adjust temperature and humidity as well as lighting and day/night cycle. The 24-hour cycle can be divided into 12 parts with each part having its own temperature, lighting conditions, and timespan set. The system is equipped with automatic temperature control and alarm with an accuracy of +/- 2.5 degrees Celsius of the set temperature. Maximum and minimum temperature limits can also be set and connected to an external alarm or reporting station.

This stainless steel seed germination chamber has an inner structure composed of a double glass window for the left and right sides, and a glass door on the front. The purpose of this structure is to prevent the heat and humidity from the lights from affecting the germination temperature. This is because the heating element is thermostatically controlled. The germination cabinet is provided with five shelves that can be placed on different heights and the doors are supplied with fluorescent lamps. For mobility, the cabinet is equipped with four wheels.

Germination Cabinet For Commercial Growing

<span style="font-weight: 400">The heating process is a step of raising the temperature of food, pharma, cosmetics, and many other types of products. You may employ different heating solutions for this process, depending on the type of product you intend to manufacture. Selecting the appropriate heater machine for your product is quite important since various products require different ranges of temperatures and different ways of heat transfer using exchangers. Industrial heating equipment varies in two ways - the type of material it can process and the reaction you want to achieve.</span>

Heating

Seed germination performance relies on factors such as seed type, cleanliness level, and in particular temperature. Having the right temperature promotes seed germination. Testing the seeds’ germination performance using one specific temperature at a time would take many trials and is a time-consuming task without the proper equipment. With a system that can test each type of seed in different temperature conditions simultaneously, you can save time finding the right germination temperature.

<h2>Testing germination performance in different temperatures simultaneously</h2>
The QGM-4300 Seed Thermogradient Table from Seed Processing Holland is a seed germination system that can apply different temperatures for each type of seed simultaneously. It is used in determining the optimum germination temperature and germination speed of seeds and seed pellets.

The system is suitable for research and development purposes where different types of seeds are tested to determine germination percentage and speed of the first 50 percent of seeds. It is also used to determine the optimum dormancy-restoring treatment temperature, and to determine germination percentage and speed after a deterioration test.

The temperature is measured by temperature sensors that are positioned in a way that you can see the germination percentage. A digital display at the front of the table is provided for the temperature reading. The cooling and heating system can set temperatures between 5 degrees Celsius to 40 degrees Celsius in a room with an average ambient temperature of 20 degrees Celsius.

Thermogradient table for seed tests

Including serialization and aggregation inspection systems to packaging lines helps manufacturers to make the distribution chain more efficient while ensuring consumer safety. Having different systems that handle serialization, aggregation and visual inspection can require different training and be time-consuming. A single system that can manage all three fuctionalities in one could be a solution to reduce effort, time, and cost.
<h2>Complete track and trace solution for serialization, aggregation and quality inspection</h2>
The Hector system from Hicof is a system with a complete track and trace system for serialization, aggregation and quality inspection. It can manage the process of serial numbering with different printing systems such as Thermo Inkjet, Continuous Inkjet or Laser printing. The Hector system has a controller that can be connected to cameras for the print inspection process. Its integrated register allows tracking processes through machines based on encoder signals. Hector system features a wide range of optical systems that helps in managing the aggregation of serialized products over multiple packaging levels. It can create individual identifiers of the aggregated container by connecting to label printing systems. Hector manages the visual quality inspection process as Pharmacode reading, filling control of Blister cavities, and quality inspection of tablets and molded products.

Serialization and aggregation inspection system

Labels provide customers with important information about both your product and your brand. Different labeling technology attaches the printed film to the packaging using a range of methods such as shrink wrapping, side sealing, and adhesives. For added traceability and protection, you may also use serialization coding equipment and anti-tampering labeling systems.

Labeling

Although the first association with almond milk might be the modern plant-based lifestyle trend, it is dated even back to the Middle Ages when it was used as an alternative to cow milk during Catholic fasting. Once harvested, almonds undergo a series of treatments in almond milk manufacturing equipment, such as bleaching, peeling, and grinding, to get the delicious final product for breakfast and desserts.

Almond milk

Creamier, sweeter and versatile are the key adjectives when talking about cashew milk, especially compared to other plant-based milk. Additionally, it is rich in vitamins B and D, as well as essential minerals. Being a blend of cashew kernels and water, the cashew nut milk processing equipment includes a peeling and washing machine, a colloid mill, and a blending tank.

Cashew milk

First mentioned on a stone slab of the Eastern Han dynasty in ancient China, soy milk has survived centuries and spread from Asia to Global consumption due to the rising popularity of plant-based alternatives. To produce soymilk, raw materials must be harvested, prepared, and blended with water and desired ingredients, such as flavors and vitamins, in soymilk processing equipment.

Soy milk

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