Industrial-scale bioreactor for new food applications
Unlock the potential of cultivated meats and alternative proteins with a bioreactor system designed for precision cell cultivation, enabling seamless scale-up from lab to industrial production in new food applications.
Cultivates and Ferments Cells for Food Production
The Axenic® C Bioreactor from GEA is an industrial-scale system specifically designed for cultivating mammalian and eukaryotic cells in the food industry, focusing on applications like cultivated meats and precision fermentation. Utilizing a stirred tank reactor approach, it allows both fed-batch and continuous cultivation processes, making it suitable for producing cultured chicken breast and plant-based protein patties. The system integrates GEA’s Virtual Bioreactor Testing technology, which employs digital twin simulations to optimize shear forces, oxygen transfer rates, and temperature settings tailored to your specific cell cultures.
Importantly, the Axenic® C is fully automated, featuring the GEA Codex® process control platform for enhanced operational stability and reduced manual intervention, minimizing contamination and maximizing process repeatability. It offers multiple gas connections and perfusion capabilities to manage gas dissolution and remove inhibitory by-products, ensuring consistent cell growth and high yield production. Compliance with food industry regulations makes it ideal for innovators in cultivated fats and new food sectors. The system supports CIP for effective cleaning, and its modular design can be customized with expert engineering support to fit seamlessly into both upstream and downstream processes, enhancing your production line’s efficiency and sustainability.
Benefits
- Boosts production efficiency with continuous, fully automated operation.
- Enhances yield reliability through precise control of shear forces and oxygen transfer.
- Lowers operational costs by integrating waste-reducing perfusion technology.
- Ensures compliance with food industry standards for cultivated and fermented products.
- Facilitates innovation with customizable setups and real-time virtual testing insights.
- Applications
- Precision fermentation,Alternative proteins,Cultivated meats,Cell cultures,Cultivated fats,New food applications,Fermentation-based foods,Plant-based foods
- End products
- Precision-fermented cheese,Synthetic pork sausage,Plant-based protein patties,Plant-based egg substitute,Lab-grown beef steak,Cultured chicken breast,Cultured fish fillets,Fermented dairy-free yogurt,Cultivated duck meat
- Steps before
- Design Study,Process Evaluation,Cell Cultivation Preparation,Oxygen and Nutrient Delivery Setup
- Steps after
- Harvesting,Sterile Barriers Application,Process Control and Monitoring,Waste Reduction and Resource Management
- Input ingredients
- mammalian cells,eukaryotic cells,animal cells,oxygen,nutrients,CO2
- Output ingredients
- grown cell cultures,cultivated meats,cultivated fats,hybrid products,non-adherent eukaryotic cell types
- Market info
- GEA is known for its expertise in engineering innovative and sustainable equipment and solutions, focusing on sectors such as food, beverages, pharmaceuticals, and energy, with a reputation for quality, efficiency, and advanced technological applications in industrial processing.
- Automation
- Fully automated
- Oxygen transfer rate
- Adjustable via virtual testing
- Shear force management
- Adjustable via virtual testing
- Temperature control
- Customizable for cell requirements
- Gas connections
- Multiple,for O2 and CO2 control
- Perfusion technology
- Optional configuration
- Fed-batch and continuous cultivation
- Available
- Monitoring and feedback control
- GEA Codex® platform
- Working Mechanism
- Stirred tank reactor
- Batch vs. Continuous Operation
- Fed-batch and continuous
- Automation Level
- Fully automated
- CIP/SIP
- Automated,24/7 operation
- Cleaning Method
- CIP / SIP
- Air Incorporation Control
- Perfusion technology with gas connections for O2 and CO2
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Tank shape
- Stirred tank reactor
- Control panel type
- Automated with GEA Codex®
- Compact footprint
- Yes
- Discharge method
- Continuous or fed-batch
- Automation
- PLC-controlled
- Feed/discharge method
- Automated continuous feeding
- Control panel type
- HMI with GEA Codex® process control platform
- Integration possibilities
- Virtual Bioreactor Testing technology
- Automation level
- Fully automated with valve feedback
- Perfusion technology
- Configurable for removal of inhibiting products