Continuous dosing and blending for pharmaceutical powders
Ensuring consistent blend uniformity and efficient material use is a key challenge in pharmaceutical manufacturing. Traditional batch processes often struggle with achieving optimal mixing of multiple powder components, leading to potential inefficiencies and quality control issues.
Optimizes blend uniformity and material use
The ConsiGma® Dosing and Blending (DB) Modules from GEA are designed to address these challenges with continuous dosing and blending operations. These modules can achieve throughputs ranging from 1 to 400 kg/h, making them suitable for both low-dose and high-throughput products. The system utilizes either a ribbon blender or a linear blender, and the Conductor 4.0 software ensures seamless process control and reporting, including OOS tracking and material genealogy. With the capability to dose and blend multiple powder materials, this system is ideal for applications in ethical, CDMO, generic, nutraceutical, or CMO operations. The system offers high blend homogeneity as all powder particles go through the same mixing event, leading to higher material yield and in-process blend uniformity control.
Benefits
- Compatible with existing equipment for minimal process disruption
- Continuous or mini-batch flow capability
- Higher blend homogeneity ensuring consistent quality
- High flexibility for varying API content
- Real-time blend uniformity control