Lyophilization for live bacteria vaccine production

Ensure precise moisture control when freeze-drying live attenuated bacteria vaccines, crucial for maintaining vaccine viability and efficacy throughout production and storage.

Executes Precise Lyophilization for Vaccine Stability

The Lyophilization Freeze Dryer from Telstar is designed for the precise and efficient lyophilization of vial-encased live attenuated bacteria vaccines. This equipment operates with a mushroom-type chamber-condenser and SCADA-controlled environment, ensuring seamless integration into automated production lines. It supports pharmaceutical and biotech sectors, providing critical freeze drying for applications such as anticancer and innovative drug formulations. With a capacity of two 10 m² freeze dryers and 200 kg ice condenser support, the system’s batch processing capability ensures high-throughput operations. Constructed for durability, under stringent GMP compliance, it features CIP/SIP systems for effective cleaning and maintenance, maintaining high hygiene standards for sensitive product handling.

Benefits

  • Ensures uniform moisture control, preserving the integrity of sensitive vaccines.
  • Minimizes operational downtime with reliable single-side loading and unloading.
  • Supports batch and pilot scale operations for versatile production needs.
  • Enhances production efficiency with SCADA-controlled automation.
  • Meets stringent GMP standards, ensuring regulatory compliance.

General


Applications
Live bacteria vaccines,Innovative drugs,Biopharmaceuticals,Anticancer drugs,Hygroscopic products,Pharmaceuticals
End products
Hygroscopic biopharmaceutical compounds,Live attenuated bacteria vaccine,Lyophilized anticancer drug formulations,Lyophilized innovative drug formulations
Steps before
Vial Filling Line,Aseptic Preparation,Emulsification,Loading Vials
Steps after
Sterilization,Unloading,Humidity Control,Packing
Input ingredients
live attenuated bacteria,vial,ice condenser
Output ingredients
lyophilized vials,freeze dried bacteria vaccine
Market info
Telstar is known for specializing in the design, engineering, and manufacturing of advanced vacuum and aerospace solutions, gaining a strong reputation for their innovative and customized equipment in pharmaceutical, medical, and scientific research sectors.

Technical Specifications


Freeze Dryer Capacity
200 kg ice condenser
Freeze Dryer Size
2 x 10 m²
Loading/Unloading
Single side loading/unloading
Chamber Type
Mushroom type chamber-condenser
CIP/SIP Capability
Yes
Unloading Control
Humidity control isolator
Control System
SCADA control package
Maintenance Access
Front slot door and rear full door

Operating Characteristics


Batch vs. continuous operation
Batch
Automation level
SCADA
Cleaning method
CIP/SIP
Humidity Control
Unloading humidity control isolator
Loading/Unloading
Single side loading/unloading

Material Compatibility


Density/particle size
0.5–2.5 g/cm³ / 50–1000 µm

Physical Characteristics


Machine footprint
2 x 10 m2
Chamber shape
Mushroom type
Loading/unloading method
Single side loading/unloading
Condenser capacity
200 kg ice
Access doors
Front loading/unloading slot door and rear maintenance full door

Custom Options


Control panel type
SCADA control package
Chamber Type
Mushroom type chamber-condenser