Lyophilization for live bacteria vaccine production
When producing live bacteria vaccines, maintaining product sterility and stability during the drying process is essential to ensure the vaccine’s efficacy and safety. Traditional drying methods may compromise these aspects, posing challenges for pharmaceutical manufacturers.
Ensure stability and sterility in vaccine production
The lyophilization system by Telstar is designed specifically for live attenuated bacteria vaccine production. Featuring two 10 m2 freeze dryers with a 200 kg ice condenser capacity, it includes a mushroom type chamber-condenser isolation valve to ensure effective separation and containment. The system supports single-side loading and unloading within an isolator environment, ensuring that the product remains sterile throughout the process. Additionally, this system incorporates CIP/SIP (Clean-In-Place/Sterilize-In-Place) functionalities, front loading/unloading slot doors, and a rear maintenance full door for easy access. The SCADA control package provides precise monitoring and control, while the unloading humidity control isolator ensures optimal environmental conditions for the final product. The system is ideal for pharmaceutical firms focused on producing stable, sterile live bacteria vaccines.
Benefits
- Maintains vaccine sterility throughout the drying process
- Supports single-side loading and unloading
- Integrated CIP/SIP for easy cleaning and sterilization
- Precise control and monitoring via SCADA control package
- Optimal conditions for product stability with unloading humidity control