Integrated granulation and drying system for pharmaceuticals

Achieve seamless granulation and drying with our fully integrated system, ideal for ensuring precise control and optimal efficiency in pharmaceutical solid dosage production.

Granuates and Dries Pharmaceutical Solids

The Integrated Pharmaceutical Granulation and Drying Systems from GEA offer a comprehensive solution for solid dosage form production. This equipment is specialized in granulating and drying processes, seamlessly integrating into pharmaceutical manufacturing lines to optimize product quality. Utilizing fluid bed processors combined with high shear mixer-granulators, these systems support continuous and batch operations for producing tablets, capsules, and controlled-release formulations. Designed with advanced PLC-based automation, these systems ensure precise control and monitoring, enhancing process efficiency while supporting CIP and WIP cleaning protocols for minimal downtime. Constructed from materials that comply with GMP and FDA standards, they promise durability and resistance to chemical corrosion, with optional configurations tailored to specific operational needs.

Benefits

  • Enhances product consistency with precise moisture control during granulation and drying.
  • Reduces labor costs and errors with integrated PLC-controlled automation.
  • Minimizes cleaning time and contamination risk with efficient CIP systems.
  • Complies with GMP and FDA standards, ensuring regulatory alignment for pharmaceutical production.
  • Customizable configurations support diverse production requirements and capacity needs.

General


Applications
Pharmaceutical tablets,Pharmaceuticals,Chemical processes,Granulation processing,Pharmaceutical solid dosage forms
End products
Coated tablets,Chemical powders,Pellets,Granules,Tablets,Active pharmaceutical ingredients (apis),Pharmaceutical powders,Bulk drugs,Effervescent tablets,Controlled release formulations,Capsules
Steps before
Weighing,Blending,Binder Preparation
Steps after
Tablet Compression,Coating,Packaging
Input ingredients
dry powders,aqueous granulations,solvent granulations,binder preparations,coating preparations
Output ingredients
granulated materials,dried products,pellets,tablets
Market info
GEA is known for its expertise in engineering innovative and sustainable equipment and solutions, focusing on sectors such as food, beverages, pharmaceuticals, and energy, with a reputation for quality, efficiency, and advanced technological applications in industrial processing.

Technical Specifications


Automation
PLC-based
Batch vs. continuous
Batch
Binder distribution
Coating preparation units
Containment
Integrated containment technology
Filtration system
Filtration units
Fluid bed process equipment
Integrated
Mixer-granulators type
Top- and bottom-drive high shear
Process and CIP control
Integrated
Process Analytical Technology
Integrated PAT analyzers
Safety,containment
Integrated into design
System integration
Fully integrated turnkey installations

Operating Characteristics


Integrated Steps
Granulation,Drying,Milling
Batch vs. Continuous Operation
Batch
Automation Level
PLC-based Automation
CIP/SIP
CIP by Design
Cleaning Method
Automated CIP
Process Control Interfaces
Graphical MMI,Online Monitoring

Material Compatibility


Cleanability
High
Biological compatibility
Pharmaceutical-grade materials
Corrosive resistance (e.g. acids)
Stainless steel
Density/particle size
Adaptable to various densities and sizes

Physical Characteristics


Modular design
Yes
Compact footprint
Designed for space optimization
Discharge method
Integrated contained materials handling
Machine footprint
Varies with modular configuration
Concealed services
Concealed lines and hoses

Custom Options


Control Panel Type
PLC-based with graphical MMI
Integration with Existing Systems
Full CIM integration,compatible with plant-wide systems
Automation Level
PLC,online monitoring,recipe handling
CIP by Design
Included with patented features
Containment Options
BUCKĀ® containment technology
Process Modules
Modular approach for fluid bed,top-,bottom-drive high shear mixer-granulators
Safety and Environmental Compliance
Explosion-proof and pressure shock standards