Bioreactor for mammalian and microbial cell cultivation
Optimize your bioprocesses with advanced temperature and heat transfer controls, ideal for scaling up cell cultivation and fermentation to achieve consistent results in high-demand production environments.
Facilitates Cell Cultivation and Fermentation Processes
The BioFlo® 320 Bioreactor from Eppendorf is an engineered-to-order solution designed for complex bioprocessing needs. Featuring both glass and single-use vessel options with interchangeable magnetic and direct drive mechanisms, it supports cell cultivation and fermentation in R&D and industrial settings alike. Ideal for producing monoclonal antibodies, biofuels, and biopolymers, it accommodates batch, fed-batch, and continuous operations with working volumes ranging from 0.6 to 10.5 liters. The bioreactor’s autoclavable design includes a borosilicate glass body and stainless steel head plate, offering robust heat transfer capabilities or gentle temperature control via a water jacket. It integrates seamlessly with bioprocess controllers and supports various impeller designs, including Rushton and marine blades. The BioFlo® 320 is compliant with GMP standards, ensuring suitability for regulated environments, and features easy cleaning with interchangeable vessel designs. Customization options and engineering support are available to meet your unique process requirements.
Benefits
- Enhances process flexibility with interchangeable vessel designs and drive options.
- Minimizes contamination risk in regulated environments with GMP-compliant features.
- Optimizes energy use for diverse processes, reducing operational costs.
- Supports scalable production from laboratory to pilot scale.
- Simplifies maintenance and cleaning with autoclavable components.
- Applications
- Vaccines,Nutraceuticals,Biopolymers,Biopharmaceuticals,Biofuel
- End products
- Ethanol,Polylactic acid,Monoclonal antibodies,Omega-3 supplements,Influenza vaccines
- Steps before
- Cell cultivation preparation,Medium formulation,Sterilization,Inoculation preparation
- Steps after
- Harvesting,Sample analysis,Purification,Filtration,Product formulation
- Input ingredients
- cell culture media,microbial media,mammalian cells,insect cells,human cell lines,bacteria,yeasts,fungi,biofuel substrates,biopolymer substrates,stem cells,vaccines raw materials,aerobic organisms,anaerobic organisms
- Output ingredients
- cultured cells,fermented bacteria,produced yeast,grown fungi,biofuels,biopolymers,vaccine products,stem cell products
- Market info
- Eppendorf is known for manufacturing high-quality laboratory equipment, including pipettes, centrifuges, and bioprocessing tools. Renowned for their precision and reliability, Eppendorf's products are widely used in scientific research and clinical laboratories worldwide.
- Working Volume Range
- 0.6 – 10.5 L
- Vessel Material
- Borosilicate glass,stainless steel
- Drive Options
- Magnetic,direct overhead
- Impeller Types
- Rushton,pitched-blade,marine,spinfilter,cell-lift,packed-bed
- Vessel Types
- Stainless-steel dished-bottom,water-jacketed
- Working volume range
- 0.6 – 10.5 L
- Batch vs. continuous operation
- Batch,Fed-batch,Continuous
- Temperature control method
- Stainless steel dish bottom / Water jacket
- Drive options
- Magnetic / Direct overhead
- Impeller types available
- Rushton,Pitched-blade,Marine,Spinfilter,Cell-lift,Packed-bed
- Application types
- Cell culture,Fermentation,Stem cell culture,Biofuel/biopolymer development,Vaccine production
- Cleaning method
- CIP/SIP
- Biological compatibility
- Cell culture,microbiology,mammalian cells
- Corrosive resistance (e.g. acids)
- Stainless steel
- Cleanability
- Autoclavable
- Operations Suitable
- Batch / Fed-batch / Continuous
- Suitable Cultures
- Mammalian / Insect / Human Cell Lines
- Specialized Applications
- Stem Cell Culture / Biofuel Development
- Tank shape
- Stainless-steel dished-bottom,water jacket
- Tank size
- 1 L,3 L,5 L,10 L
- Drive type
- Magnetic / Direct overhead
- Vessel type
- Stainless-steel / Water jacket
- Vessel size
- 1 L / 3 L / 5 L / 10 L
- Impeller type
- Rushton / Pitched-blade / Marine / Spinfilter / Cell-lift / Packed-bed
- Head plate ports
- Multiple industry standard
- Process type
- Batch / Fed-batch / Continuous
- Working volume range
- 0.6 – 10.5 L