Containment tablet coater for high-potency drugs
Ensure operator safety while achieving precise tablet coating on high-potency drugs with advanced containment and easy cleaning features.
Coats and Contains High-Potency Pharmaceutical Tablets
The SECURECOAT 250 from ACG is a cutting-edge containment tablet coater engineered for processing pharmaceuticals containing highly potent active ingredients. This machine distinguishes itself with its complete containment design, utilizing bins and split valves for safe product charging and discharging, ensuring operator safety and product integrity. The vacuum-based sampling mechanism offers precise sampling without exposure risks. Uniquely designed baffles provide effective tablet rolling, matching the coating efficiency of the SMARTCOATER X•ONE series.
The SECURECOAT 250 excels in coating applications for tablets, micro-tablets, and pellets in pharmaceutical and biopharmaceutical settings, producing end-products like oxaliplatin and paclitaxel micro-tablets, estradiol coatings, and rituximab coated tablets. It processes batches up to 250 liters, suitable for both batch and small-scale operations.
With ACG’s exclusive X•ONE command and control system, the coater offers intuitive monitoring and management, compliant with ATEX, GAMP 5, and 21 CFR Part 11 standards. The machine’s design features strategically positioned washing nozzles within a wash-in-place (WIP) rack, enabling efficient cleaning and maintenance.
Benefits
- Enhances operator safety through complete containment systems.
- Enables efficient high-potency drug coating with precise tablet rolling.
- Facilitates regulatory compliance with integrated secure control systems.
- Simplifies cleaning procedures with wash-in-place design.
- Maintains product integrity with consistent vacuum-based sampling.
- Applications
- Cytotoxic drugs,Pharmaceutical tablets,Pellets,Hormonal drugs,Micro-tablets,Biopharmaceuticals,High-potency drugs,Oncological drugs
- End products
- Oxaliplatin tablets,Doxorubicin pellets,Tramadol slow-release pellets,Rituximab coated tablets,Everolimus tablets,Abiraterone acetate tablets,Aromatase inhibitor drugs,Tamoxifen coatings,Imatinib mesylate tablets,Paclitaxel micro-tablets,Sunitinib malate capsules,Cisplatin micro-tablets,Estradiol coatings,Contraceptive hormone films,Goserelin implants
- Steps before
- Granulation,Drying,Encapsulation
- Steps after
- Packaging,Blister packaging,Cartoning
- Input ingredients
- tablets,micro-tablets,pellets,oncological drugs,cytotoxic drugs,biopharmaceutical drugs,hormonal drugs,high-potency drugs
- Output ingredients
- coated tablets,coated micro-tablets,coated pellets
- Market info
- ACG World is known for its expertise in manufacturing pharmaceutical and nutraceutical processing and packaging machinery, offering innovative equipment solutions and maintaining a strong reputation for quality and reliability in the global market.
- Working Volume
- Min 75 l,Max 250 l
- Tablet Size
- Up to 250 l batch
- Occupational Exposure Band (OEB)
- 4 compliance
- Washing method
- Wash-in-place (WIP) rack
- Control System
- ACG’s X•ONE command and control system
- Compliance
- ATEX,GAMP 5,21 CFR Part 11
- Batch vs. continuous operation
- Batch
- Automation level
- PLC/SCADA-controlled
- Contained sampling mechanism
- Vacuum-based
- Cleaning method
- Wash-in-place (WIP)
- Product handling system
- Contained with bins and split valves
- Coating efficiency
- SMARTCOATER X•ONE baffles
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Machine footprint
- Compact
- Tank shape and size
- 250 liters
- Discharge method
- Contained product charging and discharging system
- Control panel type
- X•ONE command and control system
- Control panel type
- X•ONE command and control system
- Integration possibilities
- Compatible with existing ATEX,GAMP 5,and 21 CFR Part 11 systems