Pilot-scale bioreactor for cell cultivation and fermentation
Transitioning from bench-scale cell cultivation to pilot-scale is crucial in scaling up processes for new food applications. This involves addressing challenges like oxygen transfer rates, pH control, and other critical process parameters that affect cell health and yield.

Enable seamless scale-up for cell cultivation
The GEA Axenic® P is a versatile pilot-scale bioreactor designed to bridge the gap between laboratory-scale experiments and commercial production. Engineered specifically for new food applications, this bioreactor allows you to derive key data for a smoother transition to industrial-scale manufacturing. Notable features include a package of sensors that collect key data on tank conditions, gas delivery, and uptake. Additionally, the Axenic® P’s flexibility lets you test various cell types, processes, and setups. It includes swappable components, autoclavable parts, and integrated CIP. The system also supports virtual modelling for optimizing tank conditions and predicting cell behavior at larger scales. The Axenic® P uses the GEA Codex® automation platform for recipe management and data handling, making it an intuitive and adaptable choice for diverse applications. GEA, building upon decades of expertise, has designed this unit to offer actionable insights, energy-efficient operation, and sustainability considerations for the new foods sector.
Benefits
- Accurate data collection for scaling up
- Flexible configuration for multiple applications
- Integrated CIP and autoclavable components
- Supports virtual modelling for process optimization
- Energy-efficient operation with sustainable practices