High-shear processors for uniform nanoparticles

Optimize particle size reduction and achieve uniformity in nanoparticle formulations across pharmaceuticals and food with precise high-shear processing.

Processes and Homogenizes Nanoparticles and Liquids

Dyhydromatics’ ShearJet line, including the HL60 V2, PL300, and HP1200 V2 models, delivers precise high-shear processing capabilities catering to pharmaceuticals, biotechnology, and food industries. The ShearJet HL60 V2, with its electric hydraulic drive, is designed for R&D labs, processing volumes from 3 mL to 500 mL at pressures of up to 30,000 psi. The ShearJet PL300 suits medium volume applications, offering pneumatic operation with up to 23,000 psi pressure for pharma and non-pharma uses.

For pilot-scale operations, the HP1200 V2 model provides continuous processing with customizable pressure modules, handling volumes from 250 mL to 150 liters. All models integrate seamlessly into existing production lines, supporting upstream and downstream processes with options for semi-automatic or fully automated control via HMI interfaces. They are engineered to optimize energy consumption and feature material options for corrosive environments, ensuring compliance with relevant industry standards and certifications.

These processors efficiently reduce particle sizes and homogenize various products, including nanoparticle drug formulations and emulsified compounds. They incorporate advanced cooling through innovative heat exchanger designs, maintaining product integrity while ensuring operational reliability. Dyhydromatics supports customization with engineering services to tailor equipment to specific production needs, extending machine life and reducing maintenance costs.

Benefits

  • Enhances product quality with uniform particle size distribution, ensuring consistent end-product performance.
  • Reduces operational costs by maintaining continuous processing with minimal manual intervention.
  • Optimizes energy use through precise motor control, lowering energy consumption and operational expenses.
  • Ensures regulatory compliance with available GMP and FDA standards, particularly for pharmaceutical applications.
  • Prolongs equipment lifespan with robust design and material options suitable for corrosive and demanding environments.

General


Applications
Chemicals,Personal care,Food,Biotechnology,Cannabis,Pharmaceuticals
End products
Nanoparticle drug formulations,Emulsified chemical compounds,Liposomal formulations,Personal care creams and lotions,Cannabis-infused oils and extracts,Protein suspensions,Nutraceutical liquids,Homogenized food ingredients
Steps before
Premixing,Flow monitoring,Product tank preparation
Steps after
Downstream processing,Packaging,Product outlet temperature control
Input ingredients
particle size,sample size,liquid samples,feed materials
Output ingredients
uniform particle size distributions,nanoparticles,processed products
Market info

Technical Specifications


Pressure Range
5,000 to 30,000 psi
Volume Capacity
3 mL to 500 mL and beyond
Flow Rate
68 mL/min (Small Volume),300 to 450 mL/min (Medium Volume),1L – 3.5L/min (Pilot Scale)
Stroke Volume
1 mL (Small Volume),6 mL (Medium Volume)
Cooling System
Chiller with heat exchanger
Operation Mode
Continuous Operation at Maximum Pressure
Data Acquisition
Available
User Interface
HMI with Multi-level User Interface
Cleanroom Compatibility
Pharma and non-pharma versions

Operating Characteristics


Automation level
Manual / PLC / SCADA
Batch vs. continuous operation
Batch / Inline Continuous
CIP/SIP
CIP 121°C / SIP 135°C
Energy efficiency
0.5–2 kWh/kg moisture
Cleaning method
CIP / Manual

Material Compatibility


Density/particle size
0.5–2.5 g/cm³ / 50–1000 µm

Physical Characteristics


Machine footprint
Small footprint
Noise level
70 db
Operation type
Electric hydraulic driven / Pneumatic driven
Cooling method
Product heat exchanger with chiller
Mobility
Casters for mobility between suites
Process controller
Integrated HMI

Custom Options


Control panel type
Touchscreen HMI
Integration possibilities
Manual,semi-automatic,fully automated
Additional features
Quick disconnect cooling water connections
Product path customization
Electropolished and passivated