Controller for pilot and production scale bioreactors
Optimize your bioprocess with a robust, configurable controller designed to seamlessly integrate with pilot and production bioreactors, ensuring precise control and measurement for your cultivation processes.
Controls and Integrates Bioprocesses for Pilot and Production
The Pro-Control from Getinge is an adaptable bioprocess controller designed for pilot and production scale bioreactors. Featuring compatibility with DeltaV™, Siemens, and Allen Bradley PLCs, it ensures seamless integration within any facility. Ideal for producing monoclonal antibodies, CAR-T cell therapies, and lab-grown meat, it offers flexible configuration options tailored to specific process requirements. Capable of supporting single-use or sterilizable-in-place systems, Pro-Control manages operations from batch to continuous cultivation efficiently. It boasts a comprehensive set of sensors and actuators, ensuring precise measurement and control, while adhering to cGMP standards. The controller’s design optimizes both single-use and stainless-steel bioreactor applications, facilitating energy-efficient operations and streamlined cleaning.
Benefits
- Enhances operational efficiency with seamless integration and automation.
- Complies with cGMP and 21 CFR part 11 for strict regulatory environments.
- Flexible configuration supports both single-use and sterilizable solutions, adapting to various production needs.
- Improves process accuracy with advanced sensor technology for critical parameter monitoring.
- Streamlines production changeovers, reducing downtime and enhancing productivity.
- Applications
- Media optimization, Microbial cultures, Nutraceuticals, Biopharmaceuticals, Cell and gene therapy, Cellular agriculture
- End products
- Car-t cell therapies, Probiotic cultures, Monoclonal antibodies, Lab-grown meat, Herbal supplements, Optimized cell culture media
- Steps before
- Media preparation, Cell inoculation, Sterilization of containers, Sensor calibration
- Steps after
- Sterilization in place, Batch harvesting, Downstream processing, Cleaning and disinfection
- Input ingredients
- single-use bioreactor ingredients, stainless steel bioreactor ingredients, gas, liquid, biomass, offgas measurements, pressure
- Output ingredients
- bioprocessed products, cell cultures, microbial cultures, optimized media, processed batches, fed-batch outputs, perfusion outputs, continuous cultivation products
- Market info
- Getinge is known for providing innovative healthcare and life sciences products, specializing in medical technology, infection control, surgical workflows, and critical care solutions. They maintain a strong reputation for quality and technological advancement in these sectors.
- PH Sensor
- Mettler Toledo INSUS pH sensor, Traditional Electrochemical
- DO sensor
- Mettler Toledo INSUS DO sensor, Traditional Polarographic
- Temperature Range
- 0-150 °C, accuracy 0.1°C
- Weight Measurement
- Reactor load cells and balances
- Additional I/O
- Up to 8 Analog in and 4 Analog out, Up to 8 Digital in and 8 Digital out
- Gas Control
- Up to 8 MFC's with solenoid valves or up to 8 rotameters with solenoid valves
- Liquid Control
- Up to 4 internal fixed speed pumps, Up to 2 external variable speed pumps
- Impeller Type
- Marine Impeller, Rushton, Marine, Hydrofoil
- Temperature Control
- Lauda Temperature Control Unit (TCU), Cooling and heating jacket via bioreactor wall
- Control Hardware and Software
- Siemens, Allen Bradley, iFix, DeltaV™
- Certifications
- CE certified, GAMP compliant, 21 CFR part 11 compatible
- Communication,SCADA
- Lucullus® PIMS, DeltaV™, iFix
- Getinge OPC server available
- Integration with factory systems
- DeltaV, Siemens PLC, Allen Bradley PLC, iFix
- Automation level
- Fully configurable, PLC / SCADA
- Compatibility
- Single-use and sterilizable-in-place applications
- Process type
- Batch, Fed-Batch, Perfusion, Continuous cultivation
- Flexibility
- Designed on wheels for SUPR, skid for stainless steel
- Control hardware and software platform
- Siemens, Allen Bradley, iFix, DeltaV
- CIP/SIP
- CIP 121°C / SIP 135°C
- 21 CFR part 11 compatible
- Yes
- Machine footprint
- Mobile on wheels or fixed on a skid
- Tank sizes
- 50 to 5, 000 L
- Discharge method
- N/A
- Control panel type
- Siemens or Allen Bradley
- Compact footprint
- Mobile design available
- Control panel type
- Integrated with DeltaV™, Siemens PLC, Allen Bradley PLC
- Integration possibilities
- iFix, DeltaV™, Siemens, Allen Bradley
- Design flexibility
- Wheeled design for SUPR, Skid design for stainless steel bioreactor