Compact bioreactor for cell therapy process development

Quickly scale your cell culture processes with scalable mixing technology, ensuring consistent growth conditions for efficient stem cell and MSC expansion.

Cultures and Expands Stem Cells and MSCs

The PBS-Mini Vertical-Wheel Bioreactor from PBS Biotech is a cutting-edge solution designed for precise and scalable cell culture processes. Its unique Vertical-Wheel technology facilitates gentle yet effective mixing, optimizing conditions for stem cell culture and T cell expansion. Ideal for biopharmaceutical and cell therapy applications, this bioreactor accommodates single-use vessels with working volumes of 0.1L or 0.5L, providing flexibility for various research and development needs. The system’s compatibility with incubators allows for controlled temperature and gas conditions, essential for reproducible results. Constructed with materials that meet regulatory standards, it ensures compliance for first-in-human clinical trials. The PBS-Mini is engineered for seamless integration into laboratory and pilot-scale operations, featuring removable caps for sterile sampling and harvesting, and is supported by comprehensive user resources and customization options.

Benefits

  • Enhances scalability from research to production, enabling seamless process development.
  • Improves cell culture consistency with controlled temperature and gas conditions.
  • Facilitates sterile operations, reducing contamination risk in critical expansion processes.
  • Supports regulatory compliance for clinical trials, ensuring peace of mind for developers.
  • Increases operational flexibility with interchangeable single-use vessel options.

General


Applications
Hipsc aggregates,Cell therapy,Biopharmaceuticals,Stem cell culture,Msc expansion,T cell expansion
End products
Steps before
Cell culture preparation,Media preparation,Incubator setup
Steps after
Sampling,Harvesting,Downstream processing
Input ingredients
cell culture media,single-use vessels,PBS-0.1 vessel,PBS-0.5 vessel,MSC,hiPSC,Pluripotent Stem Cells,T Cells,CellGenix reagents
Output ingredients
cultured cells,expanded MSCs,expanded hiPSCs,expanded T cells
Market info
PBS Biotech is known for manufacturing single-use, scalable bioreactor systems designed for cell therapy and biologics production, featuring their innovative Air-Wheel mixing technology for efficient and consistent results.

Technical Specifications


Working Volume
0.1L or 0.5L
Compatibility
Single-use vessels
Automation
Customizable programming
Sampling/Harvesting Method
Via unscrewing the cap and pipette
Cleanroom Compatibility
Suitable for biosafety hood
Product Contact Materials
Meets regulatory requirements
Power Supply
120-240 V
Temperature Control
Incubator use
Gas Control
Incubator use

Operating Characteristics


Mixing mechanism
Vertical-Wheel
Temperature control
Use in incubator
Gas control
Use in incubator
Sterile liquid handling
Removable caps for biosafety hood
Scalability
Scalable from mini to larger bioreactors
Batch vs. continuous operation
Batch
Automation level
Manual / Customizable process control via software

Material Compatibility


Biological compatibility
Yes
Cleanability
Removable caps for sterile liquid handling
Corrosive resistance (e.g. acids)
Meets regulatory requirements for clinical trials

Physical Characteristics


Size
0.1L or 0.5L working volumes
Shape
Vertical-Wheel
Single-use Vessel
Yes
Discharge Method
Bottom Port
Portability
Designed for use in incubator
Cap Type
Removable caps

Custom Options


Universal base compatibility
0.1L or 0.5L
Temperature and gas control capability
Designed for incubator use
Sterile liquid handling
Removable caps for biosafety hood use