15l vertical-wheel bioreactor for cell therapy scale-up

Scaling up cell culture processes to accommodate clinical trial production often requires specialized bioreactors that can handle larger volumes while maintaining cell viability and quality. The challenge lies in ensuring consistent performance and optimal hydrodynamic mixing for large particles or cell aggregates.

Customize and control your scaling process

The PBS-15 Vertical-Wheel bioreactor from PBS Biotech is designed for scaling up cell culture processes. With a working volume of up to 15 liters, it is ideal for larger scale process development or clinical trial production. The touchscreen interface allows for intuitive process customization and control, while the adjustable height harvest valve (AHHV) facilitates rapid medium exchange, sampling, and harvesting. Configurations are available for both single-use and reusable dissolved oxygen (DO) and pH sensors, ensuring flexibility in usage. The bioreactor can be placed on the floor and is equipped with wheels for easy movement. Installation and operations qualification protocols are available for compliance with industry standards.

Benefits

  • 15L capacity for scalability
  • Intuitive touchscreen interface for process control
  • Flexible sensor configuration options
  • Adjustable height harvest valve for efficient sampling
  • Wheeled design for easy placement and movement