Chromatography systems for large-scale biopharmaceutical purification
In biopharmaceutical manufacturing, the purification of complex biomolecules poses significant challenges. Accurate separation and purification tools are crucial to maintain product integrity and comply with Good Manufacturing Practices (GMP).
Achieve precise purification of biopharmaceuticals
The production-level chromatography system (AutoPrep series) from Truking is designed for pilot and large-scale production of biopharmaceuticals, such as monoclonal antibodies, insulin, blood products, vaccines, and recombinant proteins. This integrated control unit automates the balance of chromatography columns to meet purification process requirements for packing, elution, harvesting, regeneration, and cleaning. The system complies with current GMP regulations. It includes two binary plunger pumps and one sampling pump for automatic sampling, an inlet setup for up to 8 buffers and 8 sample inlets, and up to 8 outlets connected to automatic collectors. Additionally, it features a fully automatic column flow direction switching valve and remote monitoring capabilities, ensuring optimal operation at all times. Truking provides a powerful algorithm for automatic sample loading, collection, and process optimization.
Benefits
- Automated balance of chromatography columns
- Advanced bubble sensors prevent interference
- Meets GMP compliance requirements
- Remote monitoring for operational oversight
- Efficient optimization of process parameters