Automated dissolution testing with direct Hplc injection
Pharmaceutical laboratories often face challenges in ensuring accurate and efficient dissolution testing while minimizing human error and manual intervention. Issues such as sample degradation during buffering, potential cross-contamination, and time-consuming manual transfers can impact overall testing accuracy and efficiency.
Automate sampling, filtration, and Hplc/uplc injection
The ATS Xtend™ LC On-/Offline by Sotax AG is an automated system designed for direct injection of dissolution samples into HPLC/UPLC systems. This system performs unattended sampling, filtration, and injection, ensuring high repeatability and minimizing errors. It supports a wide range of filters, from tip filters to standard syringe filters, preventing clogging and saturation for various release methods. The SAM sample manager can handle multiple processes simultaneously, while optional cooling prevents sample degradation. Cross-contamination and carry-over are mitigated through a thorough cleaning routine. Advanced monitoring with CenterView™ records the dissolution process, ensuring proper procedures are followed. The system seamlessly integrates with various HPLC/UPLC brands and systems, supported by the WinSOTAX®plus software for method and data management.
Benefits
- Minimizes manual intervention and human error
- Prevents sample degradation with optional cooling
- Reduces cross-contamination with automated cleaning routines
- Supports various filters to prevent clogging
- Ensures accurate and efficient data logging