Cream Manufacturing Equipment

Find innovative production technology for making cream and connect directly with world-leading specialists.

Cream
Tell us about your production challenge
The topical route is a convenient route for the self-administration of drugs. But turning a pharmaceutical formulation into an easy-to-use cream involves specialized cream manufacturing equipment. Topical dosage forms are essentially an emulsion of oil and water.  But the ratios can be changed to process it into lotions, ointments, and gels.

Which cream technology do you need?

Wafer cutting system for cream-filled wafers

Wafer cutting system for cream-filled wafers

In high-capacity wafer production environments, achieving precision cuts in fi…

Wafer sheet cream application system

Wafer sheet cream application system

In the wafer production process, applying cream between wafer sheets can be a challengi…

Cream preparation plant for wafer production

Cream preparation plant for wafer production

In the wafer production industry, achieving a consistently mixed and high-qual…

Contact spreading machine for cream application on wafer sheets

Contact spreading machine for cream application on wafer sheets

Producing high-quality wafer sandwiches requires precise …

Intermediate cream container for snack production

Intermediate cream container for snack production

In snack production, precise storage and tempering of cream is critical …

Cream preparation plant for homogeneous mixing

Cream preparation plant for homogeneous mixing

In wafer and snack production, achieving a consistently mixed cream with a s…

Filling and sealing system for creams and lotions

Filling and sealing system for creams and lotions

In the cosmetics industry, ensuring the precise and airtight filling of …

Planetary stirrer for creams and ointments mixing

Planetary stirrer for creams and ointments mixing

In pharmaceutical and cosmetic industries, achieving uniform consistency…

Planetary stirrer for creamy and foamy masses

Planetary stirrer for creamy and foamy masses

In food and baking industries, achieving the perfect consistency in mixtures …

Gear or piston filling-dosing equipment for creamy and thick foods

Gear or piston filling-dosing equipment for creamy and thick foods

In food processing, precise dosing and filling of pro…

Turbo cream mixer for fat cream production

Turbo cream mixer for fat cream production

In confectionery manufacturing, creating smooth and consistent fat cream filling…

Cooling tunnel for cream-filled wafer blocks

Cooling tunnel for cream-filled wafer blocks

In the production of cream-filled wafers, maintaining the structural integrity…

Premixer for cream production

Premixer for cream production

Preparing fat creams for confectionery or baked goods demands precise blending of liquid and so…

Vertical mixer for creams and desserts

Vertical mixer for creams and desserts

In food and cosmetic production, achieving a perfectly uniform mixture of various cre…

Horizontal mixer for creams

Horizontal mixer for creams

In the production of creams, ensuring an optimal and uniform mix is essential. This requires prec…

Industrial cream whipping machine

Industrial cream whipping machine

Achieving consistent and stable cream texture is essential in the production of cream-base…

Vacuum mixer for liquid and cream processing

Vacuum mixer for liquid and cream processing

In the pharmaceutical, cosmetics, chemical, and food industries, achieving hom…

Vacuum homogenizer for creams and ointments

Vacuum homogenizer for creams and ointments

In cosmetic and pharmaceutical production, achieving uniform texture and stable…

Auto bakery tray depositor for creams and batters

Auto bakery tray depositor for creams and batters

In many modern bakeries, efficiently and accurately depositing creams an…

Emulsifier for cosmetic creams

Emulsifier for cosmetic creams

The process of making cream and lotion involves mixing of water phase and oil phase to create …

Cosmetic cream filler

Cosmetic cream filler

From thin liquid baby oils and perfumes to thicker lotions and creams for hair and skincare, cosmetic pr…

High shear lab mixer for creams

High shear lab mixer for creams

Lab-scale mixers are vital in the design or small-batch production of a range of pharmaceutic…

Filling machine for creams

Filling machine for creams

Liquid cosmetics have particular requirements when it comes to filling and capping containers. Mor…

Homogenizer for creams

Homogenizer for creams

Homogenization (or pharmaceutical micronization) is the process of reducing particle sizes, and is a vi…

Sanitary pigging system for viscous food products

Sanitary pigging system for viscous food products

In the food processing industry, transferring viscous products such as c…

Centrifugal separators for dairy products

Centrifugal separators for dairy products

In dairy processing, achieving high-quality milk or cream separation is vital for…

High speed cheese dosing and wrapping solution

High speed cheese dosing and wrapping solution

When packaging processed, cream, or fresh cheese in various portion shapes, …

Cartoning solution for cheese portions

Cartoning solution for cheese portions

In the production of processed, fresh, or cream cheese, efficient and reliable packag…

Homogenizers for high-pressure applications

Homogenizers for high-pressure applications

In the production of emulsions, cream, and UHT milk, maintaining stability and …

Triple shaft mixer for high viscosity products

Triple shaft mixer for high viscosity products

When producing high-viscosity products such as sealants, adhesives, or cream…

Dual shaft mixer for high viscosity products

Dual shaft mixer for high viscosity products

In industries such as adhesives, sealants, and cosmetics, mixing medium to hig…

Stainless steel cooking kettle for food, pharma, and cosmetics

Stainless steel cooking kettle for food, pharma, and cosmetics

In industries like food, pharma, and cosmetics, preparatio…

Aseptic filler for bag in box packaging

Aseptic filler for bag in box packaging

Ensuring the aseptic filling of a wide range of liquid and particulate products, suc…

Aseptic filler for liquid and particulate products

Aseptic filler for liquid and particulate products

When filling and packaging liquid products or products with particulate…

Aseptic filling system for bag-in-box packaging

Aseptic filling system for bag-in-box packaging

In the food and beverage industry, maintaining product sterility during fil…

Planetary mixer with double tool for pastry dough

Planetary mixer with double tool for pastry dough

For the production of semi-industrial and industrial pastries, maintaini…

Stories about cream

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Raise the API content to 99%


Pharmaceutical creams are mostly used to treat skin issues such as rashes, stings, or fungal infections. Unlike cosmetic creams, medicated creams penetrate the epidermis and target cells in the lower layers of the skin.


Pharmaceutical creams must contain 99% pure active ingredients. However, APIs are applied in lower concentrations than in other formulations like tablets.


Mix the water and oil phases to produce a stable emulsion

The preparation of oil and water phases involves different cream manufacturing equipment. Oils are extracted and purified from biological materials using extraction technology. Water is filtered from contaminants and distilled.

The two come together in specialized mixing systems that suspend the liquids into an emulsion. A finer droplet renders a more stable emulsion and a smoother cream consistency.

Disperse the drugs and additives in the liquids before emulsification

The oil phase can be either a mineral oil or a silicone, enriched with emollients and lubricants. If the additives are in wax form, heating equipment is used to melt them into the oil base.

Excipients such as binders, thickeners, and stabilizers help the two phases to emulsify. But these agents are dispersed into the water phase. Active ingredients are dispersed into both phases depending on their reactive properties.

Find dispersing technology

Use high-shear mixing equipment to prevent lumps


Not all mixing technologies are suitable for manufacturing pharmaceutical creams. The mechanism needs to incorporate the drugs (typically in powder form) into the emulsion droplets. Failing to combine the materials homogeneously causes agglomerate in the formulation down the line.


High-shear mixers disperse the API and excipients uniformly in the oil and water phases. Similarly, the high rate of agitation lowers the interfacial tension between the phases, producing a more stable emulsion.


Add viscosity modifiers to retain a consistent texture in creams

Excipients are used to facilitate drug delivery. But, at the same time, molecules can coalesce into a microstructure forming large crystals.

Lubricants keep the fluidity of the formulation. But changing temperatures alter their behavior, and creams may feel greasy in warmer environments. Viscosity modifiers reduce the change of stickiness in lubricants to keep a consistent structure.

How to pack your creams and ointments


When filling topical formulations it is essential to get the amount of product in various consistencies per container just right and to be able to accommodate various container shapes and sizes. There are many factors that influence the decision for choosing a container to fill in topical dosage forms. Some of these factors are materials and visual appearance while others are specific to the usage of the product filled. The most common containers for filling creams are tubes and glass or plastic jars.


Tubes have narrow openings that protect the creams against contamination and preserve the product’s shelf life. Tubes are mostly made from low or high-density polyethylene and aluminum. They have various top shapes that can be applied. For example, triangular toppers allow to push out as much product as needed with precision. Push tops are also common for creams that need controlled amounts produced with each pump. Tubes can be of different diameters ranging from 16mm to 50mm and the capacity ranging from 5ml to 240ml. A filling machine, therefore, becomes a critical piece of equipment for any cream manufacturing plant.


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