Cream Manufacturing Equipment
Find innovative production technology for making cream and connect directly with world-leading specialists.
Which cream equipment do you need?
Homogenizer for creams
Homogenization (or pharmaceutical micronization) is the process of reducing particle sizes, and is a vi…
Filling machine for creams
Liquid cosmetics have particular requirements when it comes to filling and capping containers. Mor…
High shear lab mixer for creams
Lab-scale mixers are vital in the design or small-batch production of a range of pharmaceutic…
Cosmetic cream filler
From thin liquid baby oils and perfumes to thicker lotions and creams for hair and skincare, cosmetic pr…
Emulsifier for cosmetic creams
The process of making cream and lotion involves mixing of water phase and oil phase to create …
Sachet Machine
If you want to pack into eye-catching 4-side sealed sachets between 40x50 mm and 250x200 mm in size, investing i…
Pharmaceutical formulation and mixing tanks
Preparation lines for formulating pharmaceuticals include fixed and mobile tank…
Batch vacuum mixer for emulsion-based products
The production of creams or ointments can be either be a water in oil (w/o) …
Pilot ultrasonic extractor
In the herbal medicine industry, an ultrasonic extractor is a valid alternative to conventional ex…
Pilot plant homogeniser
From food to pharma, homogenization is an essential step in the production process that provides unifo…
Complete cutting, mixing, emulsifying and heating system
From laboratory scale to large volume food or cosmetic production…
Continuous chocolate line with vertical ball mills
To mix and refine cocoa liquor, cocoa powder, sugar, and lecithin, seve…
Small batch filter press for oil seeds
Getting a high-quality oil filtration can be a challenging task, with a filtration c…
Cold oil press for seeds
With a cold oil press, you can optimize the process of extracting oil from a wide variety of oil seed…
Dispersing machine for emulsions and suspensions
Equipment operating under the rotor/stator principal is often employed whe…
Economic dispersing machine for emulsions and suspensions
For products of medium viscosity and relatively consistent part…
Dispersing machine for very fine emulsions and suspensions
For continuous high performance mixing of solid and liquid raw…
Ultra-fine dispersing machine for emulsions and suspensions
Producing the finest micro-emulsions and suspensions requires…
Colloid mill
For creating extremely fine emulsions and high quality dispersions a high pressure homogenizer is often chosen. T…
Cone mill machine
When your raw materials include agglomorated suspensions of grainy or crystalline solids and your process ne…
Corundum disk mill
Wet milling and grinding of viscous liquids or pastes containing solid particles such as peanut butter,must…
Inline batch mixer for solids and liquids
Several issues often arise when your process requires batch-wise mixing of powder…
Continuous homogenizing system
Certain mixing tasks present unique challenges and manufacturers need equipment that is specif…
High accuracy homogenizing system
When extremely high accuracy is required in your recipe or formulation traditional mixing …
Horizontal kneader
For high viscosity products, better results and reduced process times can be achieved with kneading type ra…
Vertical kneader
Production of highly viscous products with high solid content often benefits from kneading processes rather th…
Continuous kneader
Effective mixing of highly viscous products with extremely high solids content can be difficult and the res…
Batch dispersing machine
Equipment operating under the rotor/stator principal is often employed when more traditional methods …
Batch dispersing machine for abrasive products
For mixing and dispersing tasks that cannot be completed by conventional sti…
Batch dispersing machine for bottom entry into vessels
When your process requires high performance mixing or dispersion bu…
GMP homogenizing system
Manufacturers need production mixing equipment that is capable, flexible, and easy to maintain. Accura…
Cost-effective homogenizing and emulsifying system
Manufacturers of cosmetic products need mixing equipment that is capabl…
Dust-free continuous homogenizing system
Producers in a wide variety of industries benefit from equipment that can continuou…
Dilution system for two or more liquids in one pass
Onsite dilution of liquid process ingredients has historically been as…
Small-scale laboratory dispersing machine
Developing and validating new processes requires reliable and highly versatile eq…
Pilot dispersing machine for testing and scale-up
Innovators in process development need laboratory equipment that helps t…
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Homogenizer for creams
Homogenization (or pharmaceutical micronization) is the process of reducing particle sizes, and is a vi…
Filling machine for creams
Liquid cosmetics have particular requirements when it comes to filling and capping containers. Mor…
High shear lab mixer for creams
Lab-scale mixers are vital in the design or small-batch production of a range of pharmaceutic…
Cosmetic cream filler
From thin liquid baby oils and perfumes to thicker lotions and creams for hair and skincare, cosmetic pr…
Emulsifier for cosmetic creams
The process of making cream and lotion involves mixing of water phase and oil phase to create …
Sachet Machine
If you want to pack into eye-catching 4-side sealed sachets between 40x50 mm and 250x200 mm in size, investing i…
Pharmaceutical formulation and mixing tanks
Preparation lines for formulating pharmaceuticals include fixed and mobile tank…
Batch vacuum mixer for emulsion-based products
The production of creams or ointments can be either be a water in oil (w/o) …
Pilot ultrasonic extractor
In the herbal medicine industry, an ultrasonic extractor is a valid alternative to conventional ex…
Pilot plant homogeniser
From food to pharma, homogenization is an essential step in the production process that provides unifo…
Complete cutting, mixing, emulsifying and heating system
From laboratory scale to large volume food or cosmetic production…
Continuous chocolate line with vertical ball mills
To mix and refine cocoa liquor, cocoa powder, sugar, and lecithin, seve…
Small batch filter press for oil seeds
Getting a high-quality oil filtration can be a challenging task, with a filtration c…
Cold oil press for seeds
With a cold oil press, you can optimize the process of extracting oil from a wide variety of oil seed…
Dispersing machine for emulsions and suspensions
Equipment operating under the rotor/stator principal is often employed whe…
Economic dispersing machine for emulsions and suspensions
For products of medium viscosity and relatively consistent part…
Dispersing machine for very fine emulsions and suspensions
For continuous high performance mixing of solid and liquid raw…
Ultra-fine dispersing machine for emulsions and suspensions
Producing the finest micro-emulsions and suspensions requires…
Colloid mill
For creating extremely fine emulsions and high quality dispersions a high pressure homogenizer is often chosen. T…
Cone mill machine
When your raw materials include agglomorated suspensions of grainy or crystalline solids and your process ne…
Corundum disk mill
Wet milling and grinding of viscous liquids or pastes containing solid particles such as peanut butter,must…
Inline batch mixer for solids and liquids
Several issues often arise when your process requires batch-wise mixing of powder…
Continuous homogenizing system
Certain mixing tasks present unique challenges and manufacturers need equipment that is specif…
High accuracy homogenizing system
When extremely high accuracy is required in your recipe or formulation traditional mixing …
Horizontal kneader
For high viscosity products, better results and reduced process times can be achieved with kneading type ra…
Vertical kneader
Production of highly viscous products with high solid content often benefits from kneading processes rather th…
Continuous kneader
Effective mixing of highly viscous products with extremely high solids content can be difficult and the res…
Batch dispersing machine
Equipment operating under the rotor/stator principal is often employed when more traditional methods …
Batch dispersing machine for abrasive products
For mixing and dispersing tasks that cannot be completed by conventional sti…
Batch dispersing machine for bottom entry into vessels
When your process requires high performance mixing or dispersion bu…
GMP homogenizing system
Manufacturers need production mixing equipment that is capable, flexible, and easy to maintain. Accura…
Cost-effective homogenizing and emulsifying system
Manufacturers of cosmetic products need mixing equipment that is capabl…
Dust-free continuous homogenizing system
Producers in a wide variety of industries benefit from equipment that can continuou…
Dilution system for two or more liquids in one pass
Onsite dilution of liquid process ingredients has historically been as…
Small-scale laboratory dispersing machine
Developing and validating new processes requires reliable and highly versatile eq…
Pilot dispersing machine for testing and scale-up
Innovators in process development need laboratory equipment that helps t…
In-line laboratory dispersing machine
Innovators in a wide variety of industries need laboratory equipment on which processe…
Laboratory dispersing machine for low-viscous masses
Laboratory mixers have not always been easy to work with. Getting al…
Jet flow agitator for high-viscosity media
Processes including homogenization, dispersing, suspension, emulsification and d…
Agitator for medium viscosity media
Mixing fluids of medium viscosity for many production processes requires an agitator wit…
Agitator for low viscosity media
Reliably agitating fluids in open or pressure-less vessels in a laboratory or small scale pr…
High-pressure homogenizer
When processes call for homogenized emulsions with extremely fine particle sizes the traditional to…
High-speed unscrambler for large bottles
Large volume plastic bottling plants need high-speed unscramblers suitable for larg…
High-speed unscrambler for small bottles
Large-scale production of smaller volume bottled product needs a gentle, accurate y…
Low-speed unscrambler
Smaller plastic bottling lines need a lower cost, lower volume unscrambling machine that maintains gentl…
Compact monoblock filler
Filling and capping bottles and pots for food, chemical and cosmetics industries using separate machi…
Flowmeter filler
For larger production runs of food, non-food and cosmetics industries, where accuracy and volume of filling is…
In-line monoblock linear filler & capper
In many food, chemicals and cosmetic industry processes it is vital to have a …
Multi-head capper
For the stand-alone capping of bottles of up to 2.5litre capacity you need a robust and flexible machine wit…
Servo controlled filler
For food and non-food liquid products that are high foam or have a high viscosity a specialist filling…
Single head capper
For the stand-alone capping of bottles of up to 30 litre capacity for smaller-scale production you need a r…
High pressure pilot homogenizer
Biotech and pharmaceutical development programs often require a mixing method that achieves b…
High pressure industrial homogenizer
For any industrial pharmaceutical process that relies on high pressure homogenization i…
High pressure electric laboratory homogenizer
It’s vital that small units for experimentation can scale up with 100% accur…
High pressure air powered laboratory homogenizer
Offering lab-scale to small pharmaceutical production scale output for in …
Pilot high pressure homogenizer
For maximum value, a high-pressure homogenizer that’s suitable for both laboratory and pilot…
A two-component filling application tube filler
A wide variety of pharmaceutical, cosmetic and food products require tube-s…
Low speed tube filler
Increasing numbers of products in the pharmaceutical, cosmetic and food industries are delivered in flex…
Medium speed tube filler and sealer
For scale-up filling of tube packaging for pharmaceuticals, cosmetics and food products,…
Medium and high speed range automatic tube filler
When scaling up production of pharmaceutical, food or cosmetic products …
High speed automatic tube filler
For high-volume lines filling pharmaceutical, cosmetic or food products into tube containers…
Loading cassette for a tube filler
High performance tube-filling machines are used in the pharmaceutical and cosmetic indust…
Tube feeder for a small scale production tube filler
Low speed tube-filling machines are used for small scale production l…
Tube feeding unit for high volume and high speed tube filler
High performance tube-filling machines are used for large sc…
Tube unloader and feeder
The pharmaceutical and cosmetic industries utilise high speed tube fillers on large-scale production …
Vertical cartoner for pharmaceutical applications
Many pharmaceutical and cosmetic products are sold in protective and dec…
High capacity cartoner for pharmaceutical applications
Many pharmaceutical products are packed in protective and decorativ…
Horizontal cartoner for pharma and cosmetics
Most pharmaceutical and cosmetics products are packed in cardboard cartons for…
Pharmaceutical and cosmetic industry products cartoner
A large number of cosmetic and pharmaceutical products are packed i…
Automatic cartoner for applications in pharma and cosmetics
For high capacity production of cosmetics and pharmaceuticals…
High-capacity horizontal cartoner for pharma and cosmetics appliances
Cartoners take carton blanks which are formed and …
Loading basket for GMP washer
To ensure perfect cleaning of contact parts they must be placed in the GMP washer in such a way…
Entry-level chamber washer
When cleaning smaller products contacting filling or compressing components used in the production…
Bulk chamber washer
The production of cosmetics, nutraceuticals or unregulated pharmaceuticals often requires the cleaning and…
Self-adhesive linear labeling machine for bottles
It is vital to have precise and long-lasting labels on bottles to avoid …
Manual metal tube sealing equipment
For small-batch productions that utilize metal tubes as containers for their products, t…
Up to four head automatic filling machine
Increasing consumer demand forces production lines, especially packaging, to inve…
Stories about cream
Select your creams process
Tell us about your production challenge
What are you making?
Raise the API content to 99%
Pharmaceutical creams are mostly used to treat skin issues such as rashes, stings, or fungal infections. Unlike cosmetic creams, medicated creams penetrate the epidermis and target cells in the lower layers of the skin.
Pharmaceutical creams must contain 99% pure active ingredients. However, APIs are applied in lower concentrations than in other formulations like tablets.
Mix the water and oil phases to produce a stable emulsion
The preparation of oil and water phases involves different cream manufacturing equipment. Oils are extracted and purified from biological materials using extraction technology. Water is filtered from contaminants and distilled.
The two come together in specialized mixing systems that suspend the liquids into an emulsion. A finer droplet renders a more stable emulsion and a smoother cream consistency.
Disperse the drugs and additives in the liquids before emulsification
The oil phase can be either a mineral oil or a silicone, enriched with emollients and lubricants. If the additives are in wax form, heating equipment is used to melt them into the oil base.
Excipients such as binders, thickeners, and stabilizers help the two phases to emulsify. But these agents are dispersed into the water phase. Active ingredients are dispersed into both phases depending on their reactive properties.
Use high-shear mixing equipment to prevent lumps
Not all mixing technologies are suitable for manufacturing pharmaceutical creams. The mechanism needs to incorporate the drugs (typically in powder form) into the emulsion droplets. Failing to combine the materials homogeneously causes agglomerate in the formulation down the line.
High-shear mixers disperse the API and excipients uniformly in the oil and water phases. Similarly, the high rate of agitation lowers the interfacial tension between the phases, producing a more stable emulsion.
Add viscosity modifiers to retain a consistent texture in creams
Excipients are used to facilitate drug delivery. But, at the same time, molecules can coalesce into a microstructure forming large crystals.
Lubricants keep the fluidity of the formulation. But changing temperatures alter their behavior, and creams may feel greasy in warmer environments. Viscosity modifiers reduce the change of stickiness in lubricants to keep a consistent structure.
How to pack your creams and ointments
When filling topical formulations it is essential to get the amount of product in various consistencies per container just right and to be able to accommodate various container shapes and sizes. There are many factors that influence the decision for choosing a container to fill in topical dosage forms. Some of these factors are materials and visual appearance while others are specific to the usage of the product filled. The most common containers for filling creams are tubes and glass or plastic jars.
Tubes have narrow openings that protect the creams against contamination and preserve the product’s shelf life. Tubes are mostly made from low or high-density polyethylene and aluminum. They have various top shapes that can be applied. For example, triangular toppers allow to push out as much product as needed with precision. Push tops are also common for creams that need controlled amounts produced with each pump. Tubes can be of different diameters ranging from 16mm to 50mm and the capacity ranging from 5ml to 240ml. A filling machine, therefore, becomes a critical piece of equipment for any cream manufacturing plant.