Let's make serums
Find innovative production technology for making serums and connect directly with world-leading specialists.
Cosmetic serums are a very light formulation with a high density of active ingredients dispersed in oil, water, or gel. This makes serums well suited to the delivery of vitamins, antioxidants, and anti-aging ingredients, but provide less moisturization and protection. Serum production is mainly divided into stages related to optimal mixing and preventing degradation of the active ingredients.
Which serums technology do you need?
GMP homogenizing system
Manufacturers need production mixing equipment that is capable, flexible, and easy to maintain. Accura…
Cost-effective homogenizing and emulsifying system
Manufacturers of cosmetic products need mixing equipment that is capabl…
Monobloc filler and capper
If you have separate filling and capping stations you may experience lower throughput rates due to…
Benchtop peristaltic dispenser
When you fill vials and ampoules, high standards of hygiene are required to avoid the risk of …
Thin film dryers
Dry dissolved or slurried crystallizing or amorphous products to a pourable powder.
Horizontal thin film evaporators
Horizontal thin film evaporators can increase the residence time of the product and achieve …
Semi-automatic vial crimper
In a small production line, crimping vials manually can cause fatigue to your operator due to mul…
Manual ampoule filler
When you fill ampoules it is essential to avoid wetting the inside walls of the container, as it may aff…
Laboratory liquid viewer for transparent glass bottles
Impurities like hair, fibers, or glass, sourced from the environmen…
Laboratory liquid viewer for varying light conditions
In the pharmaceutical industry, you must inspect liquids in vials or…
Laboratory liquid viewer for colored glass bottles
In the pharmaceutical industry, an inspection to detect any particulate…
Benchtop piston filling equipment for vials in trays
Vials are difficult to fill individually through manual methods due t…
Benchtop ampoule opening and closing equipment
The procedure for opening or closing ampoules requires you to handle gas and…
Evaporator for heat sensitive products
The removal of solvents when making products in industries like food, cosmetics, phar…
Cosmetic cream filler
From thin liquid baby oils and perfumes to thicker lotions and creams for hair and skincare, cosmetic pr…
Self-adhesive linear labeling machine for bottles
It is vital to have precise and long-lasting labels on bottles to avoid …
Vibrating sieve for liquid solid separation
Many industrial processes require the efficient separation of solids from a slu…
High pressure air powered laboratory homogenizer
Offering lab-scale to small pharmaceutical production scale output for in …
High pressure electric laboratory homogenizer
It’s vital that small units for experimentation can scale up with 100% accur…
High pressure industrial homogenizer
For any industrial pharmaceutical process that relies on high pressure homogenization i…
High pressure pilot homogenizer
Biotech and pharmaceutical development programs often require a mixing method that achieves b…
Single head capper
For the stand-alone capping of bottles of up to 30 litre capacity for smaller-scale production you need a r…
Servo controlled filler
For food and non-food liquid products that are high foam or have a high viscosity a specialist filling…
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Multi-head capper
For the stand-alone capping of bottles of up to 2.5litre capacity you need a robust and flexible machine wit…
In-line monoblock linear filler & capper
In many food, chemicals and cosmetic industry processes it is vital to have a …
Compact monoblock filler
Filling and capping bottles and pots for food, chemical and cosmetics industries using separate machi…
High-pressure homogenizer
When processes call for homogenized emulsions with extremely fine particle sizes the traditional to…
Agitator for low viscosity media
Reliably agitating fluids in open or pressure-less vessels in a laboratory or small scale pr…
Agitator for medium viscosity media
Mixing fluids of medium viscosity for many production processes requires an agitator wit…
Jet flow agitator for high-viscosity media
Processes including homogenization, dispersing, suspension, emulsification and d…
Laboratory dispersing machine for low-viscous masses
Laboratory mixers have not always been easy to work with. Getting al…
In-line laboratory dispersing machine
Innovators in a wide variety of industries need laboratory equipment on which processe…
Pilot dispersing machine for testing and scale-up
Innovators in process development need laboratory equipment that helps t…
Small-scale laboratory dispersing machine
Developing and validating new processes requires reliable and highly versatile eq…
Dilution system for two or more liquids in one pass
Onsite dilution of liquid process ingredients has historically been as…
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Contact usMost important considerations of equipment for making serums
When making cosmetic serums, you start by preparing the oil-soluble and water-soluble constituents separately. Add active ingredients after any thermal treatments as heat may damage or destroy them. Water-based serums will typically comprise oil solubles in very low concentrations of a few percent, active ingredients in a relatively high concentration, and water-solubles forming the majority of the solution. An emulsifier facilitates the distribution of oil solubles, and a preservative protects against microbial growth.
Equipment for making serums requires mixers to prepare the initial stages and to reach a uniform consistency. These may also include thermal functions to assist the incorporation of heat-stable ingredients. You then join the two phases with the help of an emulsifier, and may now introduce your active ingredients safely. Production nuances present with the variety of serum applications, such as acne management, anti-aging, skin-shining, and the reduction of wrinkles. As a result, the selection of your formulation and the necessary accommodations to produce it successfully are important. With oil-based serums, you don’t need to process a water phase entirely for example. Gel-based serums require mixing equipment able to develop the gelling phase.
Alternative options for serum bases
Gel-based serums provide better moisturization and need a gelling agent to reach the desired consistency and texture. You still need an emulsifier to incorporate lipid components, and preservatives to prevent microbial growth. Contrary to water-based serums, their oil-based counterparts contain no water, so they don’t need emulsifiers, and to some degree preservatives. Emulsifiers can strip away the natural oils of the skin and may not be desirable in some circumstances. Consumers may also prefer preservative-free cosmetics, though these are very safe ingredients essential to maintaining shelf life in hydrated formulations. Common bases for such serums include Argan oil and Jojoba oil.
Regulatory compliance for crafting cosmetics
Regulations for production and sale of cosmetic serums vary from country to country, but prioritize safety and transparency of ingredients. The EU has defined its expectations in EU Regulation 1223/2009, for example, and includes an extensive list of banned substances. It also highlights good manufacturing practices, and requires accessibility of relevant data to track economic and medical aspects of the serum. You need to appoint a responsible party, and develop an ongoing conversation with your regulatory agency regarding the safety of your serum.
How homogenization gives you consistency
One of the most important aspects of serum production is the homogenization of its composition. A reliable serum should maintain the same look and feel in every batch. Different ingredients behave differently in solution, and clumping can produce irregularities in the texture as well as discrepancies in relative potency. When selecting equipment for making serums, consider the needs of your formula to find the optimal fit. If clumping can be an issue, use agitators to help ingredients disperse into the mixture. Prior to adding active ingredients, you may also want to heat elements to facilitate even incorporation for a smooth, uniform outcome.
