Optimized lyophilization with Smart freeze dryer technology

Streamline lyophilization cycle development with cutting-edge freeze-drying technology, designed to enhance product quality and efficiency by delivering critical process insights and reducing trial-and-error experimentation.

Automates Freeze-Drying and Data Collection

The SMART™ Freeze Dryer Technology from Scientific Products revolutionizes lyophilization by eliminating the need for traditional trial-and-error methods. Developed in collaboration with experts from the University of Connecticut and Purdue University, it features patented Manometric Temperature Measurement (MTM) for real-time monitoring of critical parameters, such as product resistance and heat flow. Ideal for applications including biopharmaceuticals, pharmaceuticals, laboratory R&D, clinical trials, and serum preparation, this system automates freeze-drying cycles to enhance efficiency and product quality. The SMART technology supports both laboratory and small production environments, providing essential data for cycle development and process scale-up. Offering options for cleanroom configurations and compliance with 21 CFR Part 11, it caters to pharmaceutical manufacturers and biotechnology firms seeking streamlined operations. The condenser coil configuration ensures optimal energy usage and reduced maintenance, facilitating a smoother integration into existing production lines.

Benefits

  • Increases productivity and reduces development time with automated cycle optimization.
  • Enhances product quality through precise monitoring of critical lyophilization parameters.
  • Decreases energy usage with efficient condenser coil configuration.
  • Supports regulatory compliance with 21 CFR Part 11 compatibility.
  • Facilitates seamless scale-up from laboratory to clinical production.

General


Applications
Clinical trials,Serum,Vials,Laboratory r,Biopharmaceuticals,D,Pharmaceuticals
End products
Biologics,Serum samples,Vaccines,Lyophilized vials,Monoclonal antibodies,Injectable drugs,Clinical trial samples,Biological drugs
Steps before
Formulation strategy development,Process development,Sample preparation,Batch setup
Steps after
Clinical trial preparation,Product packaging,Quality control testing,Product shipment
Input ingredients
serum bottles,vials,product resistance data,heat flow data,mass transfer data
Output ingredients
cake resistance,product temperature,critical parameters,freeze-drying cycles
Market info
SP Scientific is known for manufacturing high-quality freeze dryers, laboratory thermal control systems, and aseptic processing equipment, catering primarily to the pharmaceutical, biotech, and life sciences sectors with reputation for precision engineering and reliable performance.

Technical Specifications


Automation
AutoMTM feature
Cycle data collection
Product resistance,heat flow,mass transfer
Temperature measurement
Manometric Temperature Measurement (MTM)
Condenser efficiency
Maximized
Cleanroom compliance
21 CFR Part 11 available

Operating Characteristics


Automation level
Manual / PLC / SCADA
Batch vs. continuous operation
Batch
CIP/SIP
CIP 121°C / SIP 135°C
Cleaning method
CIP / Manual
Energy efficiency
0.5–2 kWh/kg moisture

Material Compatibility


Density/particle size
0.5–2.5 g/cm³ / 50–1000 µm

Product type Characteristics


Viscosity
Adaptable to various viscosities
Container size
Serum bottles and vials


21 CFR Part 11
Available as an added extra

Physical Characteristics


Discharge method
Laboratory R,D or small production freeze-drying
Control panel type
Intuitive interface
Condenser coil configuration
Maximize condenser efficiency

Custom Options


Control panel type
Intuitive Interface
Integration Possibilities
Simplified transfer of freeze-drying cycles
Cleanroom Configurations
Options available with 21 CFR Part 11 package