Optimized lyophilization with Smart freeze dryer technology
Streamline lyophilization cycle development with cutting-edge freeze-drying technology, designed to enhance product quality and efficiency by delivering critical process insights and reducing trial-and-error experimentation.
Automates Freeze-Drying and Data Collection
The SMART™ Freeze Dryer Technology from Scientific Products revolutionizes lyophilization by eliminating the need for traditional trial-and-error methods. Developed in collaboration with experts from the University of Connecticut and Purdue University, it features patented Manometric Temperature Measurement (MTM) for real-time monitoring of critical parameters, such as product resistance and heat flow. Ideal for applications including biopharmaceuticals, pharmaceuticals, laboratory R&D, clinical trials, and serum preparation, this system automates freeze-drying cycles to enhance efficiency and product quality. The SMART technology supports both laboratory and small production environments, providing essential data for cycle development and process scale-up. Offering options for cleanroom configurations and compliance with 21 CFR Part 11, it caters to pharmaceutical manufacturers and biotechnology firms seeking streamlined operations. The condenser coil configuration ensures optimal energy usage and reduced maintenance, facilitating a smoother integration into existing production lines.
Benefits
- Increases productivity and reduces development time with automated cycle optimization.
- Enhances product quality through precise monitoring of critical lyophilization parameters.
- Decreases energy usage with efficient condenser coil configuration.
- Supports regulatory compliance with 21 CFR Part 11 compatibility.
- Facilitates seamless scale-up from laboratory to clinical production.
- Applications
- Clinical trials,Serum,Vials,Laboratory r,Biopharmaceuticals,D,Pharmaceuticals
- End products
- Biologics,Serum samples,Vaccines,Lyophilized vials,Monoclonal antibodies,Injectable drugs,Clinical trial samples,Biological drugs
- Steps before
- Formulation strategy development,Process development,Sample preparation,Batch setup
- Steps after
- Clinical trial preparation,Product packaging,Quality control testing,Product shipment
- Input ingredients
- serum bottles,vials,product resistance data,heat flow data,mass transfer data
- Output ingredients
- cake resistance,product temperature,critical parameters,freeze-drying cycles
- Market info
- SP Scientific is known for manufacturing high-quality freeze dryers, laboratory thermal control systems, and aseptic processing equipment, catering primarily to the pharmaceutical, biotech, and life sciences sectors with reputation for precision engineering and reliable performance.
- Automation
- AutoMTM feature
- Cycle data collection
- Product resistance,heat flow,mass transfer
- Temperature measurement
- Manometric Temperature Measurement (MTM)
- Condenser efficiency
- Maximized
- Cleanroom compliance
- 21 CFR Part 11 available
- Automation level
- Manual / PLC / SCADA
- Batch vs. continuous operation
- Batch
- CIP/SIP
- CIP 121°C / SIP 135°C
- Cleaning method
- CIP / Manual
- Energy efficiency
- 0.5–2 kWh/kg moisture
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Viscosity
- Adaptable to various viscosities
- Container size
- Serum bottles and vials
- 21 CFR Part 11
- Available as an added extra
- Discharge method
- Laboratory R,D or small production freeze-drying
- Control panel type
- Intuitive interface
- Condenser coil configuration
- Maximize condenser efficiency
- Control panel type
- Intuitive Interface
- Integration Possibilities
- Simplified transfer of freeze-drying cycles
- Cleanroom Configurations
- Options available with 21 CFR Part 11 package