Supercritical fluid chromatography system for preparative separations
For complex substance formulations requiring rapid, precise compound isolation, this system streamlines purification, ensuring optimal purity levels essential for high-quality end products.
Purifies and Isolates Compounds Using Chromatography
The Sepiatec SFC Systems by BUCHI are fully automated supercritical fluid chromatography solutions designed for efficient compound purification and isolation in pharmaceutical, chemical, and nutraceutical industries. These systems operate on a compact, benchtop design, offering high flexibility in separations, supported by UV, ELSD, and optional mass spectrometry detection. Ideal for applications from drug development to cosmetic formulation, Sepiatec SFC handles a range of solid and liquid products, including active pharmaceutical ingredients and essential oils. Its PLC-controlled interface facilitates easy integration and automation within production lines, while modular design ensures quick maintenance and part replacement. With options for both small and large-scale purification, the systems’ energy-efficient pumps minimize solvent usage, while compliance with industry standards ensures reliability in various operational environments.
Benefits
- Enhances purification efficiency, allowing for high-quality compound isolation with minimal solvent use.
- Optimizes laboratory space with compact design suitable for benchtop or fume hood installation.
- Reduces operating costs and downtime through quick and easy maintenance with modular components.
- Increases safety and ease of operation with intuitive touchscreen controls and automated processes.
- Supports a wide range of compound purifications, making it versatile for various industrial applications.
- Applications
- Drugs,Fine chemicals,Specialty chemicals,Fragrances,Nutraceuticals,Cosmetics,Apis,Natural products
- End products
- Amino acids,Serums,Pharmaceutical tablets,Flavored oils,Aromatic compounds,Fragrance formulations,Organic acids,Vitamin supplements,Skin creams,Cosmetic colorants,Active pharmaceutical ingredients (apis) for medications,Herbal extracts,Specialty dyes,Perfume ingredients,Essential oils
- Steps before
- Purification,Synthesis,Extraction,Fermentation,Grinding
- Steps after
- Fraction Collection,Detection,Packing,Screening,Storage
- Input ingredients
- drugs,natural products,fine chemicals,specialty chemicals,cosmetics,fragrances,organic synthesis extracts
- Output ingredients
- isolated compounds,purified APIs,purified natural components,purified dietary supplements
- Market info
- Buchi is renowned for its expertise in laboratory and industrial solutions, particularly in producing high-quality equipment for chemical analysis and lab processes, known for precision and reliability in the pharmaceutical, chemical, and food industries.
- System Design
- Compact and fully automated
- Detection
- UV,ELSD,and MS (optional)
- Pump
- Prep SFC mode
- Max operating pressure
- 400 Bar
- Total flow rate at 40% modifier
- 50 ml/min,250 ml/min,660 ml/min
- Column dimensions
- 4-16 mm ID,15-30 mm ID,30-50 mm ID,max 800 mm lengths
- DAD wavelengths range
- 190-720 nm
- Injection mode
- Multiple and stacked
- Sample capacity
- mg to gram range
- Column storage
- Up to 10 columns
- Fraction collection
- Unpressurized state
- CO2recycling
- Optional
- Ease of use
- Intuitive touchscreen interface
- Automation level
- Fully automated with dedicated software
- Space efficiency
- Compact,bench-top or fume hood installation
- Sample injection method
- Multiple and stacked injections
- Fraction collection
- Unpressurized state
- Data entry method
- 15.6" touchscreen
- Detection options
- UV,ELSD,MS (optional)
- Column handling
- Up to 10 columns in oven
- Injection mode
- Stack mode with isocratic gradient
- Instrument setup
- Simple setup with exhaust system connection
- Flexibility
- Handles various sample sizes and conditions
- Pump mode
- Prep SFC mode
- Serviceability
- Modular,service-friendly design
- Software capabilities
- Parameter changes during run
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Compact footprint
- Yes
- Control panel type
- 15.6‘‘ touchscreen
- Discharge method
- Unpressurized state fraction collection
- Space saving design
- Minimal lab space required
- Control panel type
- 15.6" touchscreen