Roller compaction system for dry granulation
Achieve precise densification and consistent powder granulation with a system designed for increased material hardness and uniform sheet production, suitable for scalable pilot to production operations.
Compacts and Granulates Pharmaceutical Powders
The GFC-520 GRANUFORCE™ from Freund utilizes a unique cantilevered roll design to compact and granulate pharmaceutical powders into uniform sheets with increased density. Perfect for pharmaceutical and nutraceutical manufacturers, this system streamlines the creation of tablets, capsules, and supplements. Capable of processing between 5kg to 130kg per hour, it features a vertical tapered feed screw and serrated rolls for efficient material flow. Automation is heightened with a 12″ HMI control system, offering real-time monitoring and process validation under 21 CFR Part 11 compliance. The optional inline PAT monitoring ensures precise particle size distribution, while the Smart-Safe™ containment option elevates operational safety. Engineered for ease of cleaning and maintenance with quick changeover capabilities, the GFC-520 fits seamlessly into pilot and production settings, maximizing output while minimizing fines and product loss.
Benefits
- Enhances product consistency and quality with uniform granulation.
- Increases production efficiency with high throughput capacity.
- Minimizes product waste with a unique compaction seal design.
- Reduces manual oversight with automated and validatable process controls.
- Supports flexible manufacturing needs with scalable roll and screw design.
- Applications
- Vitamins,Supplements,Fine chemicals,Nutraceuticals,Pharmaceutical powder
- End products
- Vitamin d tablets,Omega-3 tablets,Antioxidant pills,Protein supplement powders,Dietary fiber powders,Calcium supplements,Vitamin c capsules,Iron supplements,Paracetamol tablets,Active pharmaceutical ingredients (apis)
- Steps before
- Powder Blending,Mixing,Size Reduction
- Steps after
- Tablet Pressing,Coating,Fines Reduction,Sizing
- Input ingredients
- powdered material,Lactose/Avicel Blend
- Output ingredients
- uniform compacted sheets,increased density
- Market info
- Freund is known for its expertise in granulation and coating technology, supplying high-quality industrial equipment for pharmaceutical, chemical, and food industries. Renowned for innovation and reliability, Freund consistently delivers engineered-to-order solutions tailored to client needs.
- Capacity
- 5–130 kg/hr
- Roll Width x Diameter
- 62 x 200 mm
- Roll Speed
- 3–25.5 RPM
- Maximum Roll Force
- 136 kN
- Automation
- 12″ HMI w/ External USB Collection Port
- Roll Gap Measurement
- Laser Roll Gap Control (Option)
- Particle Size Distribution
- Classifications/Recirculation Systems (Optional)
- Containment
- Smart-Safe™ Containment Optional 5µg/m3 without Isolator
- De-Aeration Design
- Inline De-Aeration Design
- Batch vs. continuous operation
- Inline Continuous
- Changeover time
- Quick Changeover Design
- CIP/SIP
- Easy Cleaning
- Cleaning method
- Manual
- Energy efficiency
- Economical Design
- Automation level
- Partial Automation with HMI Control
- Roll Adjustment
- Constant Compaction Force Within Roll Gap
- Compaction Force Adjustability
- Laser Roll Gap Control
- Containment
- Smart-Safe™ Containment Optional
- Inline Monitoring
- Inline PAT Monitoring Optional
- Abrasion resistance
- Standard serrated rolls
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Cleanability
- Easy cleaning design
- ISO Certification
- ISO 9001
- Footprint
- Compact / Space-saving
- Roll Width x Diameter
- 62 x 200 mm
- Feed method
- Vertical tapered feed screw system
- Discharge method
- Contained compaction zone
- Control panel type
- Color Touchscreen
- Portability
- Portable Self-Contained System
- Changeover Design
- Quick Changeover / Cantilevered Roll for Easy Cleaning
- Roll Design
- Serrated / Alternate Available
- Control panel type
- Color Touchscreen Control System
- Integration possibilities
- Inline PAT Monitoring
- Roll type
- Serrated / Alternate Available
- Roll movement
- Parallel Roll Movement
- Roll Gap Control
- Laser Roll Gap Control (Option)
- Containment level
- Smart-Safe™ Containment Optional
- Automation Control System
- 21 CFR Part 11 Data and Recipe Handling System
- Portability
- Portable Self-Contained System
- Vacuum De-Aeration
- Optional Vacuum De-Aeration Available