Smart miniature mass spectrometer for pharma freeze dryers
Optimize your freeze-drying process with a non-invasive tool capable of real-time gas detection and leak monitoring, ensuring product integrity and operational efficiency.
Detects and Quantifies Gases in Freeze Dryers
The QUANTUM Smart Miniature Mass Spectrometer by IMA Group is engineered for precise gas detection and quantification in freeze drying applications. This robust, ultra-compact device integrates seamlessly into existing pharmaceutical and biotech operations, enabling real-time, non-invasive monitoring. Its advanced mass filter and Faraday Cup detector accurately identify contaminants at concentrations down to ppm levels, vital for maintaining the integrity of lyophilized pharmaceuticals and fine chemicals. With plug-and-play setup, Ethernet connectivity, and modular configuration, QUANTUM supports both pilot and full-scale production environments, optimizing leak detection and ensuring consistent product quality. Designed to meet stringent industry standards, this spectrometer enhances process control and development across laboratories and processing facilities.
Benefits
- Enhances product safety by accurately detecting leaks and contaminants at sub-ppm levels.
- Boosts operational efficiency with a plug-and-play setup, streamlining integration into existing systems.
- Minimizes maintenance efforts through a robust, modular sensor design.
- Offers scalable solutions for both pilot and production environments, accommodating growth and process development.
- Improves analytical precision with remote browser-based control for tailored operation and monitoring.
- Applications
- Freeze-dried products,Biopharmaceuticals,Fine chemicals,Pharmaceuticals
- End products
- Lyophilized dietary supplements,Lyophilized therapeutics,Vaccines,Freeze-dried enzymes,Lyophilized pharmaceuticals,Lyophilized drugs,Antibodies,Lyophilized diagnostic kits,Lyophilized biologics,Lyophilized chemical reagents
- Steps before
- Preparation of freeze dryers,Installation of the mass spectrometer,System calibration,Introduction of helium for leak detection
- Steps after
- Analysis of measurement data,Leak site repair,Cycle monitoring and control,System report generation
- Input ingredients
- process gases,silicone oil,non-aqueous solvents,helium,nitrogen (N2),argon (Ar)
- Output ingredients
- quantitative real-time measurements,detection of contaminants,detection of process gases,leak detection results,primary and secondary drying analysis
- Market info
- IMA is known for its expertise in manufacturing automated packaging machines and solutions, particularly for the pharmaceutical, cosmetics, food, tea, and coffee industries, offering innovative, high-quality equipment and comprehensive customer service.
- Mass Range
- 1-100 amu
- Mass Resolution
- FWHM
- Mass number stability
- 0.1 amu
- Sensitivity
- 5e-6 A/Torr
- Minimum detectable partial pressure
- 1e-9 Torr for N2 / 1e-8 Torr for He / 1e-9 Torr for Ar
- Minimum detectable concentration (LoD)
- 1 ppm for N2 at 1 mTorr
- Maximum operational pressure
- 5e-3 Torr for N2
- Scan speed per amu
- 10 msec/amu to 10 sec/amu adjustable
- Sampling pressure range
- 1e-5 Torr – 1e+3 Torr
- Operating temperature
- 10°C to 35°C
- Electron energy
- 25 V – 100 V (70 V default setting)
- Emission current
- 0.01 – 1 mA (0.4 mA default setting)
- Accuracy
- < 1% of reading
- Startup-up time
- 3′ from out of the box
- Weight
- 9 kg
- Power consumption
- DC 24V,<100 W
- Leakage Monitoring
- Real-time,automatic
- Process Relevance
- Quantitative,real-time
- Contaminant Detection
- Ppm levels
- Automation Level
- Remote,Browser-based GUI
- Integration Ease
- Plug,Play,less than 5 minutes
- Remote Control
- Browser-based SW,Ethernet communication
- Cycle Monitoring
- Primary and Secondary Drying Detection
- Startup Time
- 3 minutes out-of-the-box
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Compact footprint
- Ultra-compact design
- Control panel type
- Web browser-based GUI
- Weight
- 9 kg
- Control panel type
- Remote browser based SW control
- Integration possibilities
- Easy integration in new or existing freeze dryers
- Software Interface
- Web browser-based software user interface
- Communication interfaces
- Ethernet (wi-fi upon request)