Benchtop bioreactors for microbial fermentation
Optimize your bioprocessing with scalable benchtop bioreactors, ideal for precise control and parallel operations in cell culture and fermentation, allowing seamless transition from lab-scale to pilot-scale production.
Facilitates Parallel Bioprocessing and Fermentation
The Ambr® 250 Modular from Sartorius is a compact benchtop bioreactor ideal for biopharmaceutical R&D and process optimization. It integrates single-use technology, enabling efficient batch, fed-batch, and perfusion processes. This system supports parallel operations with modular units ranging from 2 to 8 bioreactors, all under intuitive software control. Key applications include monoclonal antibodies, vaccines, and gene therapies, producing end-products like erythropoietin, insulin, and CAR-T cell therapies. The Ambr® 250 Modular features enhanced energy efficiency through optimized mixing and gas insertion, reducing operating costs and environmental impact. It offers autoclavable and single-use vessel options, ensuring flexibility and compatibility with various bioprocessing needs. Compliance with GMP standards guarantees suitability for regulated environments, and customizable vessel configurations allow precise process design tailored to specific applications.
Benefits
- Enhances productivity with parallel bioreactor operation, optimizing resource use.
- Lowers operational costs via energy-efficient design, reducing power consumption.
- Ensures compliance with stringent GMP standards, suitable for regulated industries.
- Offers versatile compatibility with autoclavable or single-use vessels.
- Streamlines process optimization with intuitive control software, simplifying user operation.
- Applications
- Cell culture,Biologics,Vaccines,Pharmaceuticals,Microbial fermentation,Monoclonal antibodies,Mrna production,Regenerative medicine,Biosimilars,Biopharmaceuticals,Cell and gene therapy,Bioprocessing
- End products
- Bivalent hpv vaccine,Stem cell therapies,Hepatitis b vaccine,Single-stranded mrna therapeutics,Car-t cell therapies,Erythropoietin,Insulin,Antibody-drug conjugates,Aav-based gene therapies,Trastuzumab,Recombinant proteins,Filgrastim,Viral vectors,Infliximab,Rituximab,Bevacizumab,Onasemnogene abeparvovec,Interferons,Pembrolizumab
- Steps before
- Cell Line Development,Culture Media Preparation,Sampling
- Steps after
- Downstream Processing,Filtration,Sterility Testing,Sample Preparation for Assay Development
- Input ingredients
- microbial cultures,cell cultures,media,buffers,nutrients,gases,substrates
- Output ingredients
- cultured cells,fermentation products,bioprocess materials,harvested biomass
- Market info
- Sartorius AG is renowned for manufacturing high-precision laboratory and bioprocess equipment. They specialize in filtration, fermentation, and cell cultivation systems, known for their innovation and reliability in the pharmaceutical and biotech industries.
- Vessel Volume,Autoclavable
- 1 L to 10 L
- Vessel Volume,Single-Use
- 250 mL and 2 L
- Type of Process
- Batch,Fed-Batch,Perfusion
- Number of Bioreactors in System
- 2 to 8 Modules
- System Expansion Capability
- Expandable from 2 to 8 Bioreactors
- Stirred-Tank Dimensions
- Height to Diameter Ratio Available
- Integrated Control Software
- Intuitive System Software
- Control Units
- Biostat® B-DCU,Biostat® RM
- Probe Insertions
- Multiple Ports Available
- Gas Mixing Capability
- Yes,with Central Stirrer Element
- Aeration Capability
- Provided via Stirred-Tank Design
- Material for Vessel
- Glass,Single-Wall,Double-Wall
- Bioreactor Design
- Stirred-Tank with Defined Height Dimension Ratio
- Motor Placement
- Head Plate Mounted
- Batch vs. continuous operation
- Batch / Fed-batch / Perfusion
- Automation level
- Manual / PLC / SCADA
- Cleaning method
- CIP / Manual
- Integration of process analytical tools
- Available
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Footprint
- Benchtop
- Small footprint fits on lab bench
- Vessel Type
- Single-use and multi-use vessels
- Vessel Capacity
- 1 to 10 L for autoclavable
- 250 mL and 2 L for single-use
- Control Panel
- Intuitive system software
- PLC/SCADA
- Stirrer Element
- Central stirrer driven by motor
- Ports
- Multiple ports for probe insertions,substrate addition,gas insertion,sample removal
- Modularity
- Expandable from 2 to 8 bioreactors
- Control panel type
- Intuitive system software
- Integration possibilities
- Fully integrated single-use systems
- Scalability
- 1 to 10 L multi-use,250 mL to 2 L single-use
- Independent control units
- Up to two culture units