Small size multi-use glass autoclavable bioreactor
Optimize your laboratory space with this compact bioreactor that reduces media costs and accelerates experimental data collection, perfect for innovating in microbial and cell culture applications.
Great for making:
Supports Cultivation and Optimizes Small-Scale Bioprocessing
The Applikon MiniBio is a compact, multi-use glass bioreactor designed for laboratory-scale applications, offering exceptional flexibility and efficiency for pharmaceutical and biotech operations. This autoclave-ready system minimizes media usage, optimizing bench space while supporting a range of processes, including cultivation, separation, mixing, and temperature control. Ideal for developing monoclonal antibodies, vaccines, probiotics, and enzymes, it offers true scalability from research to production phases. Equipped with a direct-drive system and optional integrated sensors for pH, DO2, and temperature, it ensures precise process control. The electrically cooled exhaust condenser reduces evaporation, enhancing operational efficiency. Customizable options include impeller and sparger configurations for versatile bioprocessing, all while aligning with GMP standards for assured quality and compliance.
Benefits
- Enhances productivity by allowing parallel experiments and quick data acquisition.
- Minimizes operating costs through reduced media consumption.
- Improves scalability, facilitating seamless transition from lab to full-scale processes.
- Offers precise control of process parameters, ensuring consistent product quality.
- Conserves bench space with compact design, supporting efficient laboratory operations.
- Applications
- Microbial cultures,Cell cultures,Nutraceuticals,Biopharmaceuticals,Enzymes,Pharmaceuticals
- End products
- Digestive enzymes,Vaccines,Monoclonal antibodies,Stem cell therapies,Herbal extracts,Probiotics
- Steps before
- Media Preparation,Inoculation,pH Adjustment,Temperature Calibration
- Steps after
- Harvesting,Cell Separation,Data Analysis,Cleaning and Autoclaving
- Input ingredients
- media,microbial cultures,cell cultures,batch,fed-batch,perfusion,continuous cultivation,micro liquid injectors,gas inputs (N2,Air,O2,CO2)
- Output ingredients
- bioprocess data,exhaust gas,cultivated biomass,cell separation device output,scalable results
- Market info
- Getinge is known for providing innovative healthcare and life sciences products, specializing in medical technology, infection control, surgical workflows, and critical care solutions. They maintain a strong reputation for quality and technological advancement in these sectors.
- Total volume
- 290 mL / 550 mL / 1250 mL
- Working volume
- 200 mL / 400 mL / 1000 mL
- Minimum working volume
- 50 mL / 100 mL / 200 mL
- Aspect ratio total volume
- 2.3 / 2.1 / 2.3
- Aspect ratio working volume
- 1.6 / 1.5 / 1.9
- Dimensions (dxh)
- 180 x 400 mm / 195 x 400 mm / 200 x 550 mm
- Dimensions for autoclaving (dxh)
- 180 x 250 mm / 195 x 250 mm / 200 x 400 mm
- Drive system
- Direct drive,lipsealed
- Maximum stirrer speed
- 50 - 2000 rpm / 50 - 2000 rpm / 50 - 1750 rpm
- Maximum impeller tip speed
- 2.3 m/s / 2.9 m/s / 3.5 m/s
- Impellers
- Choice of Rushton and Marine
- Gas sparger
- Porous sparger,open pipe sparger or jet sparger
- Gas overlay
- Yes
- Exhaust gas
- Electrically cooled exhaust gas condenser
- Sampling
- Fixed sample pipe with optional sampling system
- Draining
- Height adjustable drain pipe
- Additions
- 4 fixed inlet ports and optional micro liquid injectors
- PH Measurement
- 8 mm classic pH sensor
- PH Control
- via acid pump or CO2 gas in combination with alkali pump
- DO2 Measurement
- LumiSens Optical DO2 sensor
- DO2 Control
- via N2,Air,O2 and agitation
- Temperature Measurement
- Pt-100 sensor in thermowell in topplate
- Temperature Control
- Electrical cooling and heating jacket via bioreactor wall
- Foam Measurement
- Height adjustable conductivity based foam sensor
- Foam Control
- Anti-foam addition
- Level Measurement
- Height adjustable conductivity based level sensor
- Level Control
- Variable speed pump for liquid addition or removal
- Optional inlets
- Septum,chemostat tube,liquid entry system
- Optional sensors
- Biomass,Optical Density,O2 and CO2 off gas,weight balance
- Automation level
- Manual / PLC / SCADA
- Batch vs. continuous operation
- Batch / Inline Continuous
- CIP/SIP
- CIP 121°C / SIP 135°C
- Cleaning method
- CIP / Manual
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Application types
- Screening,media optimization,process optimization
- Culture types
- Microbial and cell culture
- Process types
- Batch,Fed-Batch,Perfusion,Continuous cultivation
- Total volume
- 290 ml,550 ml,1250 ml
- Working volume
- 200 ml,400 ml,1000 ml
- Minimum working volume
- 50 ml,100 ml,200 ml
- Aspect ratio (total volume)
- 2.3,2.1,2.3
- Aspect ratio (working volume)
- 1.6,1.5,1.9
- Dimensions (dxh)
- 180 x 400 mm,195 x 400 mm,200 x 550 mm
- Dimensions for autoclaving (dxh)
- 180 x 250 mm,195 x 250 mm,200 x 400 mm
- Compact footprint
- Yes
- Drive system
- Direct drive,lipsealed
- Maximum stirrer speed
- 50 - 2000 rpm,50 - 1750 rpm
- Maximum impeller tip speed
- 2.3 m/s,2.9 m/s,3.5 m/s
- Impellers
- Choice of Rushton and Marine
- Gas sparger
- Porous sparger,open pipe sparger or jet sparger
- Exhaust gas condenser
- Electrically cooled (evaporation <4% per day at 37°C @ 2vvm)
- Configurable head plate
- Luer fittings
- Optional sensors
- Biomass,Optical Density,O2,CO2 off gas,weight balance
- Optional inlets
- Septum,chemostat tube,liquid entry system
- Drive system
- Direct drive,lipsealed
- Gas sparger types
- Porous sparger,open pipe sparger,jet sparger
- Impeller choice
- Rushton and Marine
- Exhaust gas condenser
- Electrically cooled
- Sampling system
- Optional sampling system
- Draining system
- Height adjustable drain pipe
- Addition ports
- 4 fixed inlet ports and optional micro liquid injectors
- Control options
- pH,DO2,temperature,foam,and level control