Rocker bioreactor for cell culture processes

Achieve precise control over cell culture conditions with this rocker bioreactor, ideal for maintaining delicate balance in pH, dissolved oxygen, and temperature, crucial for optimizing production of biomolecules such as viral vectors and protein therapeutics.

Cultivates Cells and Monitors Bioprocess Conditions

The HyPerforma Rocker Bioreactor from Thermo Scientific provides a versatile solution for bioprocessing applications, featuring a configurable rocking motion ideal for the cultivation of both suspension and adherent cell cultures. Integrated with a HyPerforma G3Lab Controller and TruBio software, it offers advanced control over critical parameters such as pH, dissolved oxygen, and temperature, crucial for the production of monoclonal antibodies, viral vectors, and other protein therapeutics. Suitable for various scale operations, it accommodates 10 L, 20 L, or 50 L BioProcess Containers, ensuring flexibility in working volumes from 5 L to 25 L. The optional heating blanket protects against overheating, while the stainless steel construction ensures durability and resistance to environmental conditions. Designed for seamless integration into cGMP manufacturing workflows, it adheres to stringent quality standards, facilitating smooth scalability from pilot to commercial production stages. Customizable to specific process needs, the bioreactor supports precision in high-demand biotech, pharmaceutical, and life sciences sectors.

Benefits

  • Ensures precise cell culture conditions, enhancing product yield and quality.
  • Flexibility in working volume supports diverse production scales and processes.
  • Reduces the risk of overheating with built-in protective heating elements.
  • Streamlines integration into existing workflows with automated control systems.
  • Complies with cGMP standards, facilitating regulatory approval and market entry.

General


Applications
Cell culture media,Biopharmaceuticals,Gene therapy,Fermentation processes,Cgmp manufacturing workflows
End products
Viral vectors,Immunotherapy drugs,Monoclonal antibodies,Cell-based vaccines,Protein therapeutics,Plasmid dna,Recombinant proteins
Steps before
Cell Culture Preparation,Media Preparation
Steps after
Harvesting,Downstream Processing
Input ingredients
suspension cell culture,adherent cell culture,fermentation process materials,cell culture media,bioprocess container (BPC)
Output ingredients
culture cell products,fermentation products,bioprocess outputs,processed cell culture
Market info
Thermo Fisher Scientific is renowned for providing innovative scientific instruments, laboratory equipment, and engineered-to-order solutions across various industries, esteemed for their high-quality products and expertise in life sciences, pharmaceuticals, and biotechnology sectors.

Technical Specifications


Material
Stainless Steel
Dimensions
264 x 782 x 701 mm (10.4 x 30.8 x 27.6 in),490 mm x 835 mm x 712 mm (490.3 x 32.9 x 28.0 in.) with cover
Max. Voltage
110 to 120 V,220 to 240 V,50/60 Hz
Temperature Accuracy
±0.15°C at 15°C to 40°C (±0.25°F at 59°F to 104°F)
Weight
38.5 kg (85 lbs)
PH,DO,and Temperature Monitoring
TruFluor pH+dO2 sensor
Working Volume
5 L to 25 L
Automation
Controlled by G3Lab Controller and TruBio Software
Heating Option
Optional heating blanket

Operating Characteristics


Working mechanism
Rocking motion
Automation level
TruBio software
Batch vs. continuous operation
Batch
Cleaning method
Manual

Material Compatibility


Cleanability
Yes
Biological compatibility
Yes
Corrosive resistance (e.g. acids)
Stainless Steel Construction
Density/particle size
Varies with cell culture media

Physical Characteristics


Material
Stainless Steel
Dimensions (HxWxD)
264 x 782 x 701 mm (10.4 x 30.8 x 27.6 in),490 mm x 835 mm x 712 mm (490.3 x 32.9 x 28.0 in.) with cover
Weight
38.5 kg (85 lbs)

Custom Options


Control panel type
HyPerforma G3Lab Controller
Integration possibilities
TruBio software
Rocking motion configurability
Smooth to aggressive
Optional heating blanket
Yes,with bimetallic temperature limiting switch
Sensor integration
TruFluor pH+dO2 sensor