Dissolution profiling system for biorelevant media volumes
Optimize your lab’s efficiency by integrating this dissolution monitoring system, designed for small volume testing and rapid data collection, directly at your benchtop.
Monitors Dissolution with UV Fiber Optic Probes
The miniDISS Profiler with the Rainbow R6 configuration from Pion is a cutting-edge UV monitoring system designed specifically for pharmaceutical and biotechnology applications. This equipment is exceptional in providing flexibility for small-volume dissolution testing, crucial for the development of oral formulations and high-potency drugs. Coupled with its dip-style fiber optic probes, the system allows for dynamic UV spectral data collection as frequently as every two seconds, ensuring precise monitoring and optimization of dissolution processes. Accommodating biorelevant media volumes of 100-250 mL, it integrates seamlessly into your laboratory setup, eliminating the need for time-consuming swaps and revalidations with its eight-position stirring system and interchangeable vessel sizes. Additionally, the miniDISS Profiler operates within standard industry parameters, using Rainbow technology to support efficient benchmarking, R&D advancements, and compliance with pharmaceutical standards.
Benefits
- Enhances testing efficiency by eliminating swap out and revalidation requirements.
- Provides rapid, accurate data collection with UV spectral readings every two seconds.
- Supports small-scale operations, reducing material usage and experimental waste.
- Facilitates drug development for pediatric and high-potency formulations.
- Integrates seamlessly into laboratory workflows, saving setup and operation time.
- Applications
- Pediatric drug products,Oral formulations,High potency drug products,Pharmaceutical tablets
- End products
- Amoxicillin suspension,Ibuprofen tablets,Children's paracetamol syrup,Oncology medication capsules
- Steps before
- Formulation development,Dissolution preparation,Media preparation
- Steps after
- Data analysis,Dissolution testing,Quality control
- Input ingredients
- biorelevant media volumes,high-potency API,low concentrations,oral dosage forms,pediatric drug products,sink conditions,non-sink conditions
- Output ingredients
- UV spectra data,dissolution data,formulation development results
- Market info
- Volume range
- 100-250 mL
- Measurement range
- 200 - 720 nm UV Spectra
- Data collection speed
- Every two seconds
- Stirring positions
- Eight-position system
- Interchangeable vessel sizes
- 100 ml,150 ml,200 ml,250 ml
- Path length tips
- Interchangeable
- Batch vs. continuous operation
- Batch
- Automation level
- Automatic
- Changeover time
- Quick with low revalidation
- Cleaning method
- Manual
- CIP/SIP
- Not Applicable
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- High Potency Testing
- Yes
- Formulation Development
- Oral Dosage
- Compact footprint
- Yes
- Vessel size
- 100 ml,150 ml,200 ml,250 ml
- Stirring system
- Eight-position
- Stirring System
- Eight-position with interchangeable vessels